scholarly journals A case of early detection of Loeffler’s endocarditis by contrast-enhanced echocardiography

Author(s):  
Miaona Chen
2009 ◽  
Vol 29 (S1) ◽  
pp. 15-25 ◽  
Author(s):  
Roberto M. Lang ◽  
Victor Mor-Avi

Ultrasound ◽  
2005 ◽  
Vol 13 (2) ◽  
pp. 100-105
Author(s):  
J. M. Pilcher ◽  
R. J. Eckersley ◽  
A. K. P. Lim ◽  
N. Patel ◽  
C. L. Shovlin ◽  
...  

Hepatopulmonary syndrome (HPS) may cause profound symptomatic hypoxia in patients with chronic liver disease and can be an indication for liver transplantation. The diagnosis relies on the demonstration of intrapulmonary vascular dilatation (IVD) using either contrast-enhanced echocardiography or macro-aggregated lung perfusion scans. We sought to evaluate whether a novel technique using the microbubble agent, Echovist® (Schering AG) with Doppler intensitometry of the carotid artery would be able to identify patients who fulfilled the criteria for HPS. Contrast studies were performed in 18 patients with cirrhosis, examined in the supine and upright positions. Following injection of Echovist, continuous scanning of the common carotid was performed using grey-scale and spectral Doppler for 60 s. Positive studies were determined by online signal analysis of the Doppler signal (crackle-count). Supine and upright pulse oximetry was recorded on all patients, and formal lung function tests where clinically indicated. Two patients met the criteria for HPS. They had positive results on supine and upright scans, with an increased crackle-count when upright. Two patients had single, weakly positive results with normal pulse oximetry. No association was seen between a positive contrast study and the severity of liver disease. Contrast-enhanced carotid Doppler intensitometry is a relatively simple, non-invasive test that may help identify patients with IVD. Comparison with an established technique will be required in future trials to determine its accuracy and assess whether the crackle-count can reliably quantify the degree of IVD.


2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
S Liang

Abstract Background Left ventricular ejection fraction (LVEF) and global longitudinal strain (GLS) are two important index for the quantification of left ventricular systolic function. With the help of ultrasound contrast agents, we can improve the definition of endocardial borders and allow the quantification of LVEF in patients with poor image quality. However, the feasibility of GLS measurements in contrast-enhanced images is still controversial. Purpose Our study aimed to explore the feasibility of GLS measured by velocity vector imaging (VVI) in contrast-enhanced images, compare the difference of measurements in contrast-enhanced and non-contrast images, and analyze the relation between LVEF and GLS in both conditions. Methods A total of 133 patients with cancer, who were registered for transthoracic echocardiography as well as contrast-enhanced echocardiography were studied. LVEF was measured using the biplane modified Simpson's rule and GLS was measured with offline VVI analysis of the three standard apical views in non-contrast and contrast-enhanced images respectively. Linear regression was performed to derive correlation coefficients between LVEF and GLS both in non-contrast and contrast-enhanced images. Results GLS measurements in non-contrast images were discarded in 2/133 patients (1.5%), while in contrast-enhanced images were obtained in all patients. LVEF (64.12±7.47% vs. 66.25±8.61%, respectively; P<0.01) and GLS (−20.99±4.67% vs. −23.40±4.58%, respectively; P<0.01) were both significantly higher in the presence of contrast agents. A linear regression between LVEF and GLS in non-contrast images (r=0.627, P<0.001) was observed, as well as in contrast-enhanced images (r=0.649, P<0.001). Conclusions GLS measured by VVI in contrast-enhanced echocardiography is a feasible and reliable index for the quantification of left ventricular systolic function, even in patients with poor image quality. Compared with the measurements in non-contrast images, both LVEF and GLS measurements are higher in the presence of contrast agents.


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