scholarly journals Psychosocial factors involved in preterm birth

Psihiatru ro ◽  
2021 ◽  
Vol 1 (64) ◽  
pp. 14
Author(s):  
R. Stoenescu ◽  
M. Stancu ◽  
L.E. Andrei ◽  
I. Sandu ◽  
I. Jipescu ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Psychosocial Factors

Effect of a Nonoptimal Cervicovaginal Microbiota and Psychosocial Stress on Recurrent Spontaneous Preterm Birth

2020 ◽  
Author(s):  
Kristin D. Gerson ◽  
Clare Mccarthy ◽  
Jacques Ravel ◽  
Michal A. Elovitz ◽  
Heather H. Burris
Keyword(s):  
Preterm Birth ◽  
Psychosocial Factors ◽  
Perceived Stress ◽  
High Stress ◽  
Secondary Analysis ◽  
Black Population ◽  
Spontaneous Preterm Birth ◽  
Term Birth ◽  
Key Points ◽  
Final Cohort

Objective While select cervicovaginal microbiota and psychosocial factors have been associated with spontaneous preterm birth, their effect on the risk of recurrence remains unclear. It is also unknown whether psychosocial factors amplify underlying biologic risk. This study sought to determine the effect of nonoptimal cervicovaginal microbiota and perceived stress on the risk of recurrent spontaneous preterm birth. Study Design This was a secondary analysis of a prospective pregnancy cohort, Motherhood and Microbiome. The Cohen's Perceived Stress Scale (PSS-14) was administered and cervical swabs were obtained between 16 and 20 weeks of gestation. PSS-14 scores ≥30 reflected high perceived stress. We analyzed cervicovaginal microbiota using 16S rRNA sequencing and classified microbial communities into community state types (CSTs). CST IV is a nonoptimal cervicovaginal microbial community characterized by anaerobes and a lack of Lactobacillus. The final cohort included a predominantly non-Hispanic Black population of women with prior spontaneous preterm birth who had recurrent spontaneous preterm birth or term birth and had stress measurements (n = 181). A subanalysis was performed in the subset of these women with cervicovaginal microbiota data (n = 74). Multivariable logistic regression modeled adjusted associations between CST IV and recurrent spontaneous preterm birth, high stress and recurrent spontaneous preterm birth, as well as high stress and CST IV. Results Among the 181 women with prior spontaneous preterm birth, 45 (24.9%) had high perceived stress. We did not detect a significant association between high stress and recurrent spontaneous preterm birth (adjusted odds ratio [aOR] 1.67, 95% confidence interval [CI]: 0.73–3.85). Among the 74 women with prior spontaneous preterm birth and cervicovaginal microbiota analyzed, 29 (39.2%) had CST IV; this proportion differed significantly among women with recurrent spontaneous preterm birth (51.4%) compared with women with term birth (28.2%) (p = 0.04). In models adjusted for race and marital status, the association between CST IV and recurrent spontaneous preterm birth persisted (aOR 3.58, 95% CI: 1.25–10.24). There was no significant interaction between stress and CST IV on the odds of spontaneous preterm birth (p = 0.328). When both stress and CST IV were introduced into the model, their associations with recurrent spontaneous preterm birth were slightly stronger than when they were in the model alone. The aOR for stress with recurrent spontaneous preterm birth was 2.02 (95% CI: 0.61–6.71) and for CST IV the aOR was 3.83 (95% CI: 1.30–11.33). Compared to women with neither of the two exposures, women with both high stress and CST IV had the highest odds of recurrent spontaneous preterm birth (aOR = 6.01, 95% CI: 1.002–36.03). Conclusion Among a predominantly non-Hispanic Black cohort of women with a prior spontaneous preterm birth, a nonoptimal cervicovaginal microbiota is associated with increased odds of recurrent spontaneous preterm birth. Adjustment for perceived stress may amplify associations between CST IV and recurrent spontaneous preterm birth. Identification of modifiable social or behavioral factors may unveil novel nonpharmacologic interventions to decrease recurrent spontaneous preterm birth among women with underlying biologic risk. Key Points

204 Psychosocial factors and preterm birth among African-American and white women in Central North Carolina

2001 ◽  
Vol 185 (6) ◽  
pp. S137
Author(s):  
Nancy Dole ◽  
David Savitz ◽  
Anna Siega-Riz ◽  
Michael McMahon ◽  
Barbara Eucker ◽  
...  
Keyword(s):  
North Carolina ◽  
African American ◽  
Preterm Birth ◽  
Psychosocial Factors ◽  
White Women

Relationships among psychosocial factors, biomarkers, preeclampsia, and preterm birth in African American women: A pilot

2015 ◽  
Vol 28 (1) ◽  
pp. e1-e6 ◽  
Author(s):  
Carmen Giurgescu ◽  
Natthananporn Sanguanklin ◽  
Christopher G. Engeland ◽  
Rosemary C. White-Traut ◽  
Chang Park ◽  
...  
Keyword(s):  
African American ◽  
Preterm Birth ◽  
African American Women ◽  
Psychosocial Factors ◽  
American Women

Pregnancy Intendedness, Maternal Psychosocial Factors and Preterm Birth

2005 ◽  
Vol 9 (4) ◽  
pp. 403-412 ◽  
Author(s):  
Lynne C. Messer ◽  
Nancy Dole ◽  
Jay S. Kaufman ◽  
David A. Savitz
Keyword(s):  
Preterm Birth ◽  
Psychosocial Factors ◽  
Pregnancy Intendedness

scholarly journals Relationships between psychosocial factors during pregnancy and preterm birth in Puerto Rico

PLoS ONE ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. e0227976
Author(s):  
Stephanie M. Eick ◽  
John D. Meeker ◽  
Andrea Swartzendruber ◽  
Rafael Rios-McConnell ◽  
Phil Brown ◽  
...  
Keyword(s):  
Puerto Rico ◽  
Preterm Birth ◽  
Psychosocial Factors

scholarly journals Psychosocial Factors and Preterm Birth Among African American and White Women in Central North Carolina

2004 ◽  
Vol 94 (8) ◽  
pp. 1358-1365 ◽  
Author(s):  
Nancy Dole ◽  
David A. Savitz ◽  
Anna Maria Siega-Riz ◽  
Irva Hertz-Picciotto ◽  
Michael J. McMahon ◽  
...  
Keyword(s):  
North Carolina ◽  
African American ◽  
Preterm Birth ◽  
Psychosocial Factors ◽  
White Women

scholarly journals Effects of social and psychosocial factors on risk of preterm birth in black women

2010 ◽  
Vol 24 (6) ◽  
pp. 546-554 ◽  
Author(s):  
Dawn Misra ◽  
Donna Strobino ◽  
Britton Trabert
Keyword(s):  
Preterm Birth ◽  
Black Women ◽  
Psychosocial Factors

scholarly journals Preterm birth and social support services for prenatal depression and social determinants

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255810
Author(s):  
Rebecca Reno ◽  
Johanna Burch ◽  
Jodi Stookey ◽  
Rebecca Jackson ◽  
Layla Joudeh ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Health Services ◽  
Behavioral Health ◽  
Psychosocial Factors ◽  
Social Determinants ◽  
Gestational Age ◽  
Depression Symptoms ◽  
Behavioral Health Services ◽  
Gestational Age At Birth ◽  
Age At Birth

Preterm birth (PTB; <37 weeks gestation), is a leading cause of infant mortality and morbidity. Among those born preterm, risk increases as gestational age at birth decreases. Psychosocial factors such as depression symptoms and social determinants of health (SDH) may increase risk for PTB. Research is needed to understand these risk factors and identify effective interventions. This retrospective cohort study recruited English- and Spanish-speaking women presenting symptoms of preterm labor or admitted for PTB from an urban county hospital in the San Francisco Bay Area (n = 47). We used an iterative analytic approach by which qualitative data informed an exploratory quantitative analysis. Key exposures were presence of self-reported depression symptoms during pregnancy, SDH along eight domains, and receipt of behavioral health services. The outcome was gestational age at birth. T-tests, Wilcoxon rank sum tests, and linear regression models were used to test associations between the exposures and gestational age. Most participants were Black (25.5%) or Latina (59.6%). After adjusting for covariates, participants with depression symptoms had an average gestational age 3.1 weeks shorter (95% CI: -5.02, -1.20) than women reporting no symptoms. After adjusting for covariates, high number of adverse social determinants (≥ 4) suggested an association with shorter gestational age (p = 0.07, 1.65 weeks, 95% CI: -3.44, 0.14). Receipt of behavioral health services was associated with a significantly later gestational age; the median difference was 5.5 weeks longer for depression symptoms, 3.5 weeks longer for high social determinants, and 6 weeks longer for depression symptoms and high social determinants. Among a cohort of high-risk pregnant women, both depression symptoms during pregnancy and co-occurring with exposure to high adverse SDH are associated with shorter gestational age at birth, after controlling for psychosocial factors. Receipt of behavioral health services may be an effective intervention to address disparities in PTB.

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