Recently, we have been witnessing a rapid increase in the use of machine learning techniques in self-adaptive systems. Machine learning has been used for a variety of reasons, ranging from learning a model of the environment of a system during operation to filtering large sets of possible configurations before analyzing them. While a body of work on the use of machine learning in self-adaptive systems exists, there is currently no systematic overview of this area. Such an overview is important for researchers to understand the state of the art and direct future research efforts. This article reports the results of a systematic literature review that aims at providing such an overview. We focus on self-adaptive systems that are based on a traditional Monitor-Analyze-Plan-Execute (MAPE)-based feedback loop. The research questions are centered on the problems that motivate the use of machine learning in self-adaptive systems, the key engineering aspects of learning in self-adaptation, and open challenges in this area. The search resulted in 6,709 papers, of which 109 were retained for data collection. Analysis of the collected data shows that machine learning is mostly used for updating adaptation rules and policies to improve system qualities, and managing resources to better balance qualities and resources. These problems are primarily solved using supervised and interactive learning with classification, regression, and reinforcement learning as the dominant methods. Surprisingly, unsupervised learning that naturally fits automation is only applied in a small number of studies. Key open challenges in this area include the performance of learning, managing the effects of learning, and dealing with more complex types of goals. From the insights derived from this systematic literature review, we outline an initial design process for applying machine learning in self-adaptive systems that are based on MAPE feedback loops.
A Chemoinformatic Exploration of the Chemical Space of Natural Steroids.
