scholarly journals Extrapulmonary small cell carcinoma. Literature review

2021 ◽  
Vol 23 (3) ◽  
pp. 442-446
Author(s):  
Nadezhda F. Orel ◽  
Irina V. Poddubnaya
Keyword(s):  
Cell Carcinoma ◽  
Clinical Course ◽  
Female Genital Tract ◽  
Small Cell ◽  
Low Grade ◽  
Depth Study ◽  
High Proliferative Activity ◽  
Extrapulmonary Small Cell Carcinoma ◽  
Number Of Publications ◽  
Female Genital

The review shows the features of rare tumors extrapulmonary small cell carcinomas (EPSCC). The possible approaches for the treatment of this unfavorable group of tumors are discussed. EPSCC can occur in every organ. The clinical course and morphology of EPSCC are similar to small lung cell carcinoma (SCLC). EPSCC belongs to the group of low-grade neuroendocrine tumors with high proliferative activity. There are a small number of publications in the literature concerning EPSCC. Basically, these publications concerning the various clinical cases with comments. Most often, EPSCC occurs in the female genital tract, gastrointestinal tract, genitourinary SCC and known cases of SCC of the head and neck. The cases concerning SCC in other organs are also described. For the treatment of EPSCC are usually applied guidelines developed for SCLC, and several publications on the use of immunotherapy in the treatment of EPSCC have already appeared. The analysis of the available literature let us suggest EPSCC is a big problem that requires a more in-depth study and consensus guidelines adoption for the management of these patients.

Thin-Layer Cytology Findings of Small Cell Carcinoma of the Lower Female Genital Tract

2003 ◽  
Vol 47 (1) ◽  
pp. 56-64 ◽  
Author(s):  
Wai-Kuen Ng ◽  
Leslie K. N. Cheung ◽  
Albert S. M. Li ◽  
Simon K. M. Tse ◽  
Siu-Wah Pang ◽  
...  
Keyword(s):  
Thin Layer ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Genital Tract ◽  
Female Genital Tract ◽  
Small Cell ◽  
Female Genital

scholarly journals Small Cell Cancer of the Genitourinary Tract: A Case Report and Review of the Literature

2017 ◽  
Vol 10 (2) ◽  
pp. 489-492 ◽  
Author(s):  
Ho Man Yeung ◽  
Chetan Jeurkar ◽  
Tiffany Pompa ◽  
Michael Styler
Keyword(s):  
Urinary Tract ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
African American Male ◽  
Clinical Course ◽  
Cell Cancer ◽  
Upper Urinary Tract ◽  
Small Cell ◽  
Neuroendocrine Cells ◽  
Extrapulmonary Small Cell Carcinoma

Small cell carcinoma of the urinary tract is an extremely rare disease with very few cases reported in the literature. Its clinical course is aggressive, and the prognosis is poor. Here, we present a case of metastatic extrapulmonary small cell carcinoma of the upper urinary tract in a 74-year-old African-American male. He initially presented with gross hematuria, 20-pound weight loss, and abdominal pain for 2 months. CT imaging showed a 14.0 × 7.0 × 16.0 cm retroperitoneal mass within the left renal fossa; biopsy revealed a carcinoma which was positive for synaptophysin and chromogranin. The patient also had detectable neuroendocrine cells in his urine cytology, confirming the diagnosis of small cell carcinoma. He was treated with carboplatin and etoposide as extrapolated from the treatment of its pulmonary counterpart. Due to the rarity of urinary tract small cell carcinoma, no randomized studies exist to guide therapy or management.

Low-grade Serous Neoplasia of the Female Genital Tract

2019 ◽  
Vol 12 (2) ◽  
pp. 481-513 ◽  
Author(s):  
Ann K. Folkins ◽  
Teri A. Longacre
Keyword(s):  
Genital Tract ◽  
Female Genital Tract ◽  
Low Grade ◽  
Female Genital

scholarly journals Patterns of relapse in extrapulmonary small cell carcinoma: retrospective analysis of outcomes from two cancer centres

BMJ Open ◽  
2015 ◽  
Vol 5 (1) ◽  
pp. e006440-e006440 ◽  
Author(s):  
S. Gennatas ◽  
J. Noble ◽  
S. Stanway ◽  
R. Gunapala ◽  
R. Chowdhury ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Retrospective Analysis ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Extrapulmonary Small Cell Carcinoma

scholarly journals Emerging Therapeutic Concepts and Latest Diagnostic Advancements Regarding Neuroendocrine Tumors of the Gynecologic Tract

Medicina ◽  
2021 ◽  
Vol 57 (12) ◽  
pp. 1338
Author(s):  
Tiberiu-Augustin Georgescu ◽  
Roxana Elena Bohiltea ◽  
Octavian Munteanu ◽  
Florentina Furtunescu ◽  
Antonia-Carmen Lisievici ◽  
...  
Keyword(s):  
Neuroendocrine Tumors ◽  
Neuroendocrine Carcinoma ◽  
Classification System ◽  
Who Classification ◽  
Small Cell ◽  
International Agency ◽  
Low Grade ◽  
High Grade ◽  
Small Cell Neuroendocrine Carcinoma ◽  
Female Genital

Neuroendocrine neoplasms (NENs) are particularly rare in all sites of the gynecological tract and include a variety of neoplasms with variable prognosis, dependent on histologic subtype and site of origin. Following the expert consensus proposal of the International Agency for Research on Cancer (IARC), the approach in the latest World Health Organization (WHO) Classification System of the Female Genital Tumours is to use the same terminology for NENs at all body sites. The main concept of this novel classification framework is to align it to all other body sites and make a clear distinction between well-differentiated neuroendocrine tumors (NETs) and poorly differentiated neuroendocrine carcinomas (NECs). The previous WHO Classification System of the Female Genital Tumours featured more or less the same principle, but used the terms ‘low-grade neuroendocrine tumor’ and ‘high-grade neuroendocrine carcinoma’. Regardless of the terminology used, each of these two main categories include two distinct morphological subtypes: NETs are represented by typical and atypical carcinoid and NEC are represented by small cell neuroendocrine carcinoma (SCNEC) and large cell neuroendocrine carcinoma (LCNEC). High-grade NECs, especially small cell neuroendocrine carcinoma tends to be more frequent in the uterine cervix, followed by the endometrium, while low-grade NETs usually occur in the ovary. NENs of the vulva, vagina and fallopian tube are exceptionally rare, with scattered case reports in the scientific literature.

scholarly journals Dedifferentiated Acinic Cell Carcinoma of the Parotid Gland With Myoepithelial Features

2002 ◽  
Vol 126 (9) ◽  
pp. 1104-1105 ◽  
Author(s):  
Simonetta Piana ◽  
Alberto Cavazza ◽  
Corrado Pedroni ◽  
Rosa Scotti ◽  
Luigi Serra ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Cell Carcinoma ◽  
Clinical Course ◽  
Acinic Cell Carcinoma ◽  
Low Grade ◽  
High Grade ◽  
Epithelial Proliferation ◽  
Acinic Cell

Abstract Dedifferentiated acinic cell carcinoma of the salivary gland is an uncommon variant of acinic cell carcinoma, characterized by the coexistence of both an usual low-grade acinic cell carcinoma and a high-grade dedifferentiated component, as well as by an accelerated clinical course. We describe a case of acinic cell carcinoma of the parotid gland in a 67-year-old woman, which recurred 4 times after surgery and radiotherapy. The recurrences consisted of residual foci of acinic cell carcinoma intermingled with a high-grade epithelial proliferation; the latter was focally constituted by cells with morphologic and immunohistochemical features of myoepithelium.

Primary Extrapulmonary Small Cell Carcinoma of the Appendix - A Case Report -

2010 ◽  
Vol 44 (1) ◽  
pp. 101
Author(s):  
Jong Hyeok Park ◽  
Ki Jae Park ◽  
Young Hoon Roh ◽  
Mee Sook Roh
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Extrapulmonary Small Cell Carcinoma

Small cell cancers of the female genital tract: Molecular and clinical aspects

2018 ◽  
Vol 149 (2) ◽  
pp. 420-427 ◽  
Author(s):  
Jay R. Patibandla ◽  
Julia E. Fehniger ◽  
Douglas A. Levine ◽  
Petar Jelinic
Keyword(s):  
Genital Tract ◽  
Female Genital Tract ◽  
Small Cell ◽  
Clinical Aspects ◽  
Female Genital
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