scholarly journals Features of zofenopril and enalapril in patients with stable ischemic heart disease in combination with arterial hypertension

2016 ◽  
Vol 7 (2) ◽  
pp. 42-46
Author(s):  
A. G Evdokimova ◽  
A. V Smetanin ◽  
V. V Evdokimov ◽  
E. V Kovalenko ◽  
E. V Kiyakbaeva
Keyword(s):  
Quality Of Life ◽  
Blood Pressure ◽  
Heart Disease ◽  
Arterial Hypertension ◽  
Clinical Laboratory ◽  
Functional Class ◽  
Daily Monitoring ◽  
Stable Coronary Heart Disease ◽  
Diurnal Profile

Objective. Optimization of drug therapy in patients with stable coronary heart disease and arterial hypertension (AH) in the application of ACE inhibitors: zofenopril compared with enalapril. Material and methods. We studied 80 patients with stable angina II-III functional class (FC) and AG 1-2 degree (Mean age 58.8±8.8 years) who were randomly divided into 2 groups of observation for 40 people in each: 1 - receiving zofenopril, 2 - enalapril - composed of basic therapy consisting of nitrates, .-blocker, statin, aspirin. The duration of follow-up was 6 months. At baseline and in the dynamics of all patients underwent clinical, laboratory and instrumental studies. It evaluated the quality of life through «Seattle questionnaire» for patients with angina. The daily monitoring of blood pressure at the same time with an electrocardiogram, treadmill test according to the modified protocol R.Bruce, echocardiography was conducted. Conclusion. The use of zofenopril, more than enalapril leads to significantly improved quality of life, exercise tolerance, normalizes the diurnal profile of blood pressure, reduces episodes of ischemia.

scholarly journals Gender differences efficiency of various dosage regimes of antihypertensive agents by patients with arterial hypertension and coronary heart disease

2018 ◽  
Vol 15 (3) ◽  
pp. 21-26
Author(s):  
V V Skibitsky ◽  
E V Gorodetskaya ◽  
E A Kudryashov ◽  
A V Fendrikova ◽  
A V Skibitsky
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Arterial Hypertension ◽  
Antihypertensive Therapy ◽  
Antihypertensive Agents ◽  
Functional Class ◽  
Angiotensin Ii Receptor Blocker ◽  
Angiotensin Ii Receptor ◽  
Men And Women ◽  
Stable Coronary Heart Disease

Aim - to assess the effect of different dosing regimens for combined antihypertensive therapy with the use of ACE inhibitor zofenopril or angiotensin II receptor blocker valsartan on the blood pressure (BP) profile in men and women with arterial hypertension (AH) and stable coronary heart disease (CHD). Materials and methods. 198 patients (98 men and 100 women) with AH and stable CHD (stable angina of II functional class) were examined. In men and women, the effectiveness of 3 variants of antihypertensive therapy was evaluated: a combination of metoprolol succinate/hydrochlorothiazide + zofenopril or valsartan 160 mg once or valsartan 80 mg 2 times/day. Initially and 24 weeks later, 24-hour BP monitoring was performed. Results. Among men, BP

Mood disorders impaired quality of life but not the mortality or morbidity risk in stable coronary heart disease patients

2019 ◽  
Vol 75 (7) ◽  
pp. 667-675 ◽  
Author(s):  
Otto Mayer ◽  
Jan Bruthans ◽  
Jitka Seidlerová ◽  
Petra Karnosová ◽  
Markéta Mateřánková ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Mood Disorders ◽  
Stable Coronary Heart Disease ◽  
Morbidity Risk ◽  
Impaired Quality

scholarly journals Intervensi Diet Rendah Garam Pada Pada Pasien Yang Menjalani Hemodialisis: Review Literatur

2019 ◽  
Vol 4 (2) ◽  
Author(s):  
Siti Yartin ◽  
Syahrul Syahrul ◽  
Elly L Sjattar
Keyword(s):  
Quality Of Life ◽  
Blood Pressure ◽  
Heart Disease ◽  
Hemodialysis Patients ◽  
Health Complaints ◽  
Scientific Publications ◽  
Salt Reduction ◽  
Salt Diet ◽  
Low Salt

Background: Application of low salt diet interventions to reduce health complaints and the risk of heart disease in hemodialysis patients.                                    Method: Search related articles through scientific publications by entering keywords in the PubMed, ScienceDirect, and Google Scholar databases        Results: From the 6 articles reviewed, the low salt diet intervention gave changes to systolic and diastolic blood pressure, provided a change in the level of sodium excretion, changes in quality of life and had self efficacy against salt reduction.   Conclusion: It is important for nurses, especially hemodialysis nurses, to optimize education regarding the importance of a low-salt diet of less than 2 grams per day through food and beverages consumed, or in the process of preparing and cooking food.

The effect of rivaroxaban low doses on the stable angina of the II–III functional class clinical manifestations and the quality of life in patients with ischemic heart disease

Kardiologiia ◽  
2021 ◽  
Vol 61 (9) ◽  
pp. 47-51
Author(s):  
A. A. Nekrasov ◽  
E. S. Timoshchenko ◽  
T. A. Nekrasova ◽  
M. V. Timoshchenko ◽  
A. V. Suleimanova
Keyword(s):  
Quality Of Life ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Acetylsalicylic Acid ◽  
Stable Angina ◽  
Clinical Manifestations ◽  
Functional Class ◽  
Ischemic Heart ◽  
Short Acting

Aim      To evaluate the effect of low-dose rivaroxaban on quality of life of patients and clinical manifestations of functional class (FC) II-III stable angina.Material and methods  26 patients with ischemic heart disease (IHD) with FC II-III stable angina, who were newly prescribed rivaroxaban 2.5 mg twice a day in combination with acetylsalicylic acid 75-100 mg, were followed for 10 weeks. During the first (before the beginning of treatment) and the last weeks of study, patients kept diaries, in which they reported angina attacks and short-acting nitrate intake, filled in an angina questionnaire (SAQ), and underwent electrocardiogram (ECG) Holter monitoring (HM).Results The treatment was associated with decreases in the frequency of angina attacks (by 19.5 %; р=0.027) and the number of taken short-acting nitrate pills (by 17.1 %; р=0.021) and an improvement of quality of life according to stability scales (р=0.042). Data from ECG HM showed decreases in the number and duration of ischemic episodes (p≤0.05).Conclusion      The treatment of IHD patients with rivaroxaban 2.5 mg twice a day in combination with acetylsalicylic acid 75-100 mg for 2 mos. was associated with decreased frequency of angina attacks, reduced requirement for short-acting nitrate, and with improvement of quality of life.

scholarly journals Influence of dosed walking on the course of arterial hypertension in patients with chronic obstructive pulmonary disease

2020 ◽  
Vol 1 (3) ◽  
pp. 68-74
Author(s):  
O. N. Kryuchkova ◽  
M. A. Bubnova ◽  
S. E. Bubnov
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Blood Pressure ◽  
Chronic Obstructive Pulmonary Disease ◽  
Arterial Hypertension ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Role Functioning ◽  
Obstructive Pulmonary Disease

Objective: to study the influence of dosed walking on the course of hypertension and quality of life in patients with chronic obstructive pulmonary disease.Materials and methods: the study included 85 patients with a combination of arterial hypertension and chronic obstructive pulmonary disease, with an average age of 60.9 ± 1.06 years. Group A patients were prescribed dosed walking in addition to medication, while group B patients received only antihypertensive medications, statins, and basic treatment for chronic obstructive pulmonary disease. The effectiveness of treatment was determined after 6 weeks based on a standard examination, daily monitoring of blood pressure and ECG, and quality of life indicators. Long-term results were evaluated after 6 months.Results: patients whose treatment plan included physical training, in contrast to patients receiving only medication, noted a decrease in complaints of headache (p=0.034), dizziness (p=0.041), tachycardia (p=0.029), general weakness (p=0.003), head noise and tinnitus (p=0.018), sleep disturbance (p=0.010) and shortness of breath (p=0.004). They had normalization of all indicators of quality of life according to the SF-36 questionnaire: scales physical functioning (p<0.001), role functioning due to physical condition (p<0.001), pain intensity (p<0.001), general health (p=0.002), vital activity (p=0.001), social functioning (p=0.013), role functioning due to emotional state (p<0.001), mental health (p=0.008), physical component of health in general (p<0.001) and the mental health component (p=0.002). Improvement of well-being was accompanied by normalization of lipidogram indicators, daily heart rate and blood pressure: reduction of average daily indicators of blood pressure (p<0.001), pressure load index (p<0.001), blood pressure variability (p<0.05), pulse pressure (p<0.001) and the rate of morning rise in blood pressure (p<0.001).Conclusion: addition to standard medical therapy of dosed walking has a positive effect on the course of arterial hypertension in patients with chronic obstructive pulmonary disease.

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