scholarly journals Awareness about antioxidant activities of chlorogenic acid among dental students

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 757-759
Author(s):  
Nithyanandham Masilamani ◽  
Dhanraj Ganapathy
Keyword(s):  
Antioxidant Activity ◽  
Free Radical ◽  
Chlorogenic Acid ◽  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Dental Students ◽  
Free Radical Scavenging ◽  
Scavenging Effect ◽  
Radical Scavenging Effect ◽  
Free Radical Scavenging Effect

Chlorogenic Acid (CA) is the formation of an ester established among caffeic and quinic acid. CA contains hydroxyl based groups over an aromatic moiety and exhibits very effective anticancer, antimutational and antioxidant activities. This survey was performed for assessing the awareness about antioxidant activities of CA amongst dental students. A cross-sectional survey was performed with a pretested questionnaire with ten questions disseminated among 100 dental students. The questionnaire assessed the awareness about CA therapy, their dietary sources, medicinal uses, antioxidant activity, anti ischaemic activity and free radical scavenging effect of chlorogenic acid. The responses were recorded and analyzed. 7% were aware of dietary sources,5% were aware of medical uses, 5% were aware of mechanisms of antioxidant activity, 4 % were aware of the anti ischaemic activity, and 5% were aware of the free radical scavenging effect of chlorogenic acid. Awareness about the usage of CA therapy is very less among dental students. Increased awareness programs and sensitization programs should be conducted to improve the awareness levels.

Egyptian Propolis: 3. Antioxidant, Antimicrobial Activities And Chemical Composition Of Propolis From Reclaimed Lands

2002 ◽  
Vol 57 (3-4) ◽  
pp. 395-402 ◽  
Author(s):  
Ahmed G. Hegazi ◽  
Faten K. Abd El Hady
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antioxidant Activity ◽  
Antibacterial Activity ◽  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Scavenging Effect ◽  
Radical Scavenging Effect ◽  
Free Radical Scavenging Effect

The free radical scavenging effect of two propolis samples collected from reclaimed land, Egypt as well as of vitamin C and caffeic acid in 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical system was determined. The antimicrobial (Staphylococcus aureus; Escherichia coli and Candida albicans) activity was also investigated. The results of the free radical scavenging effect of El-Saff and Ismailia propolis showed a concentration-dependent activity. The antioxidant activity was varied according to the examined material. It was obvious that caffeic acid and vitamin C showed the highest activity if compared with the propolis samples. El- Saff propolis had a higher antioxidant activity than Ismailia propolis, it showed a higher antibacterial activity against Staphylococcus aureus and a higher anti-fungal activity against Candida albicans. While the Ismailia propolis had a higher antibacterial activity against Escherichia coli, than El-Saff propolis. The chemical composition of propolis samples was investigated by GC/MS, where 75 compounds were identified, 22 being new for propolis. The Ismailia propolis was characterized by the presence of a highly significant amount of aromatic acid esters (47.3%) and triterpenoids (17.3%), while El-Saff propolis contained 3% and 1.9% respectively. The new esters belonged to 4-methoxyhydrocinnamic acid, hydroferulic acid and ferulic acid. El-Saff propolis had a very high significant amount (27%) of 2,6-bis-(pentanyloxy)-4-pentanylphenethanol, which is also a new compound for propolis

Free Radical Scavenging Activity and Secondary Metabolites from in vitro Cultures of Sanicula graveolens

2007 ◽  
Vol 62 (7-8) ◽  
pp. 555-562 ◽  
Author(s):  
José Cheel ◽  
Guillermo Schmeda-Hirschmann ◽  
Miguel Jordan ◽  
Cristina Theoduloz ◽  
Jaime A. Rodríguez ◽  
...  
Keyword(s):  
Free Radical ◽  
Chlorogenic Acid ◽  
Radical Scavenging ◽  
Root Culture ◽  
Free Radical Scavenging ◽  
Total Phenolic ◽  
Scavenging Effect ◽  
Radical Scavenging Effect ◽  
Free Radical Scavenging Effect

An in vitro propagation system was developed to obtain shoot and root cultures from the Andean spice Sanicula graveolens (Apiaceae). Propagation of shoots, roots and plantlets was achieved by the temporary immersion system. The free radical scavenging effect of the methanol/ water (7 :3 v/v) extracts was determined by the discoloration of the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH). Total phenolic, flavonoid, chlorogenic acid (CA) and quercetin 3-O-glucoside content in the samples was assessed by spectrophotometry and DAD-HPLC analysis, respectively. On a dry weight basis, the crude extracts showed total phenolic values ranging from 3.57 to 6.93%, with highest content for the root culture sample. Total flavonoid content ranged from 1.23 to 2.23% and was lower for the root culture. Chlorogenic acid and neochlorogenic acid were identified by TLC in all samples. Highest free radical scavenging effect was observed for the root culture which also presented the highest CA content. Two of the shoot culture samples, with similar IC50 values in the DPPH discoloration assay, also presented close quercetin-3-O-glucoside content

scholarly journals Antioxidant and Free Radical Scavenging Effect of D-Carvone in Hypertensive Rats In Vivo and In Vitro Study

2015 ◽  
Vol 35 ◽  
pp. 6-12 ◽  
Author(s):  
Thiyagarajan Rajeshwari ◽  
Boobalan Raja
Keyword(s):  
Body Weight ◽  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Enzymatic Antioxidants ◽  
Hypertensive Rats ◽  
Scavenging Effect ◽  
Induced Hypertension ◽  
Radical Scavenging Effect ◽  
Free Radical Scavenging Effect

This study was planned to assess the antioxidant and free radical scavenging effect of D-carvone against L-NAME (Nω-nitro-L-arginine methyl ester hydrochloride) induced hypertension. Hypertension was encouraged in adult male albino rats of the Wistar strain, considering 180–230 g, by oral administration of the L-NAME (40 mg/kg/ body weight/day) in drinking water for 4 weeks. Rats were cured with D-carvone (5, 10 and 20 mg/kg body weight) for four weeks. A significant reduction in the levels of non-enzymatic antioxidants such as vitamin C, vitamin E and reduced glutathione (GSH), in plasma were perceived in L-NAME induced hypertensive rats. Moreover, in vitro free radical scavenging activity of ABTS+ and DPPH• radical scavenging possible of D-carvone was also quantified. Treatment with D-carvone (5, 10 and 20 mg/kg bw) carries back all the above parameters to near usual level, in which 20 mg/kg displayed the highest effect than that of other two doses. Further, D-carvone displays concentration dependent antioxidant potential. These results suggest that D-carvone acts as an antioxidant and free radical scavenging agent against L-NAME induced hypertension.

Free Radical Scavengers from Cymbopogon citratus (DC.) Stapf Plants Cultivated in Bioreactors by the Temporary Immersion (TIS) Principle

2007 ◽  
Vol 62 (5-6) ◽  
pp. 447-457 ◽  
Author(s):  
Alejandro Tapia ◽  
José Cheel ◽  
Cristina Theoduloz ◽  
Jaime Rodríguez ◽  
Guillermo Schmeda-Hirschmann ◽  
...  
Keyword(s):  
Free Radical ◽  
Chlorogenic Acid ◽  
Radical Scavenging ◽  
Free Radical Scavengers ◽  
Cymbopogon Citratus ◽  
Temporary Immersion ◽  
Scavenging Effect ◽  
Neochlorogenic Acid ◽  
Radical Scavenging Effect ◽  
Free Radical Scavenging Effect

The biomass production of Cymbopogon citratus shoots cultivated in bioreactors according to the temporary immersion (TIS) principle was assessed under different growth conditions. The effect of gassing with CO2-enriched air, reduced immersion frequency, vessel size and culture time on total phenolic and flavonoid content and free radical scavenging effect of the methanolic extracts was measured. From the TIS-culture of C. citratus, seven compounds were isolated and identified as caffeic acid (1), chlorogenic acid (2), neochlorogenic acid (3), p-hydroxybenzoic acid (4), p-hydroxybenzoic acid 3-O-β-d-glucoside (5), glutamic acid (6) and luteolin 6-C-fucopyranoside (7). The occurrence of compounds 1-7 and their variability in C. citratus grown under different TIS conditions was determined by HPLC. The free radical scavenging effect of the methanolic extract and compounds was measured by the discoloration of the free radical 1,1- diphenyl-2-picrylhydrazyl (DPPH). The main metabolites in 6- and 8-week-old cultures, both in 5 and 10 l vessels, were chlorogenic acid (2) (100D113 mg%) and neochlorogenic acid (3) (80 - 119 mg%), while in the cultures with CO2-enriched air and reduced immersion frequency the main compound detected in the extracts was glutamic acid (6) (400 and 670 mg% for the green and white biomass and 619 and 630 mg% for the green and white biomass, respectively). The most active compounds, as free radical scavengers, in the DPPH discoloration assay were caffeic acid (1), chlorogenic acid (2), neochlorogenic acid (3) and the flavonoid luteolin 6-C-fucopyranoside (7).

Sign in / Sign up

Export Citation Format

Share Document