scholarly journals ASSESSMENT OF CORRELATION OF LACTATE /ALBUMIN RATIO IN SEPSIS PATIENTS ADMITTED IN ICU

2021 ◽  
Vol 1 (1) ◽  
pp. 11-16
Author(s):  
KotbAbbass Metwalley Khalil ◽  
Leif Jansson

Sepsis is life-threatening organ dysfunction caused by dysregulated host responses to infection, and septic shock is a subset of sepsis in which underlying circulatory and cellular/metabolic abnormalities are sufficiently profound to substantially increase mortality. Patients with sepsis are usually treated in the intensive care unit (ICU). Hence; under the light of above-mentioned data, the present study was undertaken for determining the correlation of lactate /albumin ratio in outcome of patients of sepsis in ICU. The present study was undertaken for determining the correlation of lactate /albumin ratio in outcome of patients of sepsis in ICU. A total of 30 patients were enrolled. The resulting patients were subjected to detailed history and examination followed by investigations (CBC, ESR, CRP), Bacterial culture, liver function test, renal function test, arterial blood gas analysis for lactate, serum albumin level). Mean Lactate value was 4.59 while mean albumin value was 25.12. Mean lactate to albumin ratio was 0.18. While correlating lactate to albumin ratio with Serum Procalcitonin levels, significant results were obtained. While correlating lactate to albumin ratio, it was seen that higher lactate to albumin ratio was associated with higher mortality. Lactate/albumin ratio is an independent predictor for the mortality among sepsis patients admitted to ICU.

Author(s):  
Kishorilal Prajapati ◽  
Aparna Trivedi ◽  
Ms. Nivedita Prajapati

Background: Method: This study was done at Department Of Medicine. All patients admitted with malaria in tertiary care Centre during the study period AIMS, Dewas from Sep 2018 to Aug 2019 were taken for the study after considering the inclusion and exclusion criteria. Our study is a clinical, prospective, observational and open study. Each patient was studied in detail with relevant clinical history and examination with following various investigations like peripheral smear for malarial parasite, complete blood count, renal function test , liver function test ,blood sugar level, USG abdomen ,chest x-ray , urine routine and micro and some special investigations like arterial blood gas analysis, bleeding profile. Result: Total of 4 patients had developed hypoglycemia of which 1 had P.vivax, 1 had P.falciparum while 2 had mixed infection. Acidosis was seen in 25 patients in arterial blood gas analysis among which 21 patients had metabolic acidosis, 4 had mixed acidosis. 5 patients had developed ARDS and 5 patients had cerebral malaria. Total 3 (6%) patient died in our study, amongst them 2 patient had mixed infection and 1 had complicated P.falciparum. The cause of death was cerebral malaria in all the case and MODS with ARDS. The entire patient died had multiple complications no mortality was there in patient with single complication.  Conclusion: Early detection of complications causing organ dysfunction utilizing Serum Creatinine >3mg/dl, total bilirubin >3mg/dl and Hb<8g/dl is valuable in diagnosing complicated malaria early and starting aggressive management, thereby preventing further morbidity and mortality. Early detection of malaria and institution of prompt antimalarial can help to prevent complication of malaria. Early diagnosis of prompt complication and proper referral of patient to tertiary health care center can help to reduce the mortality and morbidity of the patient and gives a favorable outcome. Keywords: Outcome, Complications, Malaria & Life.


2011 ◽  
Vol 2011 ◽  
pp. 1-3
Author(s):  
L. L. W. Verhaert

Case. A 45-year-old man with a blank medical history presented at the emergency room with dizziness and cyanosis. Physical examination showed cyanosis with a peripheral saturation (SpO2) of 85%, he did not respond to supplemental oxygen. Arterial blood gas analysis showed a striking chocolate brown colour. Based on these data, we determined the arterial methaemoglobin concentration. This was 32%. We gave 100% oxygen and observed the patient in a medium care unit. The next day, patient could be discharged in good condition. Further inquiry about exhibitions and extensive history revealed that the patient used MDMA (3,4- methylenedioxymethamphetamine, the active ingredient of ecstasy).Conclusion. Acquired methaemoglobinemia is a condition that occurs infrequently, but is potentially life threatening. Different nutrients, medications, and chemicals can induce methaemoglobinemia by oxidation of haemoglobin. The clinical presentation of a patient with methaemoglobinemia is due to the impossibility of O2binding and transport, resulting in tissue hypoxia. Important is to think about methaemoglobin in a patient who presents with cyanosis, a peripheral saturation of 85% that fails to respond properly to the administration of O2. Because methaemoglobin can be reduced physiologically, it is usually sufficient to remove the causative agent, to give O2, and to observe the patient.


1985 ◽  
Vol 32 (2) ◽  
pp. 112-118
Author(s):  
Seong Gyu Hwang ◽  
Su Taik Uh ◽  
Byung Soo Ahn ◽  
Dong Cheul Han ◽  
Choon Sik Park ◽  
...  

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