scholarly journals Methaemoglobinemia Induced by MDMA?

2011 ◽  
Vol 2011 ◽  
pp. 1-3
Author(s):  
L. L. W. Verhaert
Keyword(s):  
Clinical Presentation ◽  
Good Condition ◽  
Blood Gas Analysis ◽  
Supplemental Oxygen ◽  
Gas Analysis ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
Brown Colour ◽  
Arterial Blood Gas Analysis ◽  
Life Threatening

Case. A 45-year-old man with a blank medical history presented at the emergency room with dizziness and cyanosis. Physical examination showed cyanosis with a peripheral saturation (SpO2) of 85%, he did not respond to supplemental oxygen. Arterial blood gas analysis showed a striking chocolate brown colour. Based on these data, we determined the arterial methaemoglobin concentration. This was 32%. We gave 100% oxygen and observed the patient in a medium care unit. The next day, patient could be discharged in good condition. Further inquiry about exhibitions and extensive history revealed that the patient used MDMA (3,4- methylenedioxymethamphetamine, the active ingredient of ecstasy).Conclusion. Acquired methaemoglobinemia is a condition that occurs infrequently, but is potentially life threatening. Different nutrients, medications, and chemicals can induce methaemoglobinemia by oxidation of haemoglobin. The clinical presentation of a patient with methaemoglobinemia is due to the impossibility of O2binding and transport, resulting in tissue hypoxia. Important is to think about methaemoglobin in a patient who presents with cyanosis, a peripheral saturation of 85% that fails to respond properly to the administration of O2. Because methaemoglobin can be reduced physiologically, it is usually sufficient to remove the causative agent, to give O2, and to observe the patient.

scholarly journals ASSESSMENT OF CORRELATION OF LACTATE /ALBUMIN RATIO IN SEPSIS PATIENTS ADMITTED IN ICU

2021 ◽  
Vol 1 (1) ◽  
pp. 11-16
Author(s):  
KotbAbbass Metwalley Khalil ◽  
Leif Jansson
Keyword(s):  
Blood Gas Analysis ◽  
Albumin Level ◽  
Gas Analysis ◽  
Host Responses ◽  
Albumin Ratio ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
Arterial Blood Gas Analysis ◽  
Function Test ◽  
Life Threatening

Sepsis is life-threatening organ dysfunction caused by dysregulated host responses to infection, and septic shock is a subset of sepsis in which underlying circulatory and cellular/metabolic abnormalities are sufficiently profound to substantially increase mortality. Patients with sepsis are usually treated in the intensive care unit (ICU). Hence; under the light of above-mentioned data, the present study was undertaken for determining the correlation of lactate /albumin ratio in outcome of patients of sepsis in ICU. The present study was undertaken for determining the correlation of lactate /albumin ratio in outcome of patients of sepsis in ICU. A total of 30 patients were enrolled. The resulting patients were subjected to detailed history and examination followed by investigations (CBC, ESR, CRP), Bacterial culture, liver function test, renal function test, arterial blood gas analysis for lactate, serum albumin level). Mean Lactate value was 4.59 while mean albumin value was 25.12. Mean lactate to albumin ratio was 0.18. While correlating lactate to albumin ratio with Serum Procalcitonin levels, significant results were obtained. While correlating lactate to albumin ratio, it was seen that higher lactate to albumin ratio was associated with higher mortality. Lactate/albumin ratio is an independent predictor for the mortality among sepsis patients admitted to ICU.

scholarly journals Healthy blue man: congenital methemoglobinemia

2017 ◽  
Vol 5 (10) ◽  
pp. 4632
Author(s):  
B. V. Nagabhushana Rao ◽  
S. C. Sinha ◽  
S. Modi ◽  
S. Sunita
Keyword(s):  
Methylene Blue ◽  
Ascorbic Acid ◽  
Clinical Presentation ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Treatment Modalities ◽  
Blood Gas ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
Arterial Blood Gas Analysis

Congenital methemoglobinemia, though often discussed in medical teachings is rarely encountered in clinical practice as the condition is asymptomatic. Here we present such a case and discuss in detail the clinical presentation of both congenital and acquired methemoglobinemia. We also outlined the management of the conditions. One should suspect methemoglobinemia when cyanosis is not being corrected by supplementing oxygen and and when the oxygen saturation is low by pulse oximetry and normal by arterial blood gas analysis. Treatment modalities for congenital methemoglobinemia is of cosmetic purpose, but timely intervention in acquired methemoglobinemia could be lifesaving. Methylene blue, Ascorbic acid and Riboflavin are drugs of choice.

scholarly journals The Predicitive Value of Arterial Blood Gas Analysis and Radiologic Scores in ARDS

1985 ◽  
Vol 32 (2) ◽  
pp. 112-118
Author(s):  
Seong Gyu Hwang ◽  
Su Taik Uh ◽  
Byung Soo Ahn ◽  
Dong Cheul Han ◽  
Choon Sik Park ◽  
...  
Keyword(s):  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Blood Gas ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
Arterial Blood Gas Analysis

scholarly journals Usefulness of Clinical Prediction Rules, D-dimer, and Arterial Blood Gas Analysis to Predict Pulmonary Embolism in Cancer Patients

2017 ◽  
Vol 32 (2) ◽  
pp. 148-153
Author(s):  
Asifa Karamat ◽  
Shazia Awan ◽  
Muhammad Ghazanfar Hussain ◽  
Fahad Al Hameed ◽  
Faheem Butt ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Blood Gas ◽  
Clinical Prediction ◽  
Prediction Rules ◽  
Arterial Blood Gas ◽  
Arterial Blood ◽  
Arterial Blood Gas Analysis ◽  
D Dimer
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