Optimal Conductor Selection Using Grey Wolf Optimization

2016 ◽  
Vol 4 (3) ◽  
pp. 39
Author(s):  
Ramanaiah M. LAXMIDEVI ◽  
REDDY M. DAMODAR ◽  
◽  
2020 ◽  
Author(s):  
Kin Meng Wong ◽  
Shirley Siu

Protein-ligand docking programs are indispensable tools for predicting the binding pose of a ligand to the receptor protein in current structure-based drug design. In this paper, we evaluate the performance of grey wolf optimization (GWO) in protein-ligand docking. Two versions of the GWO docking program – the original GWO and the modified one with random walk – were implemented based on AutoDock Vina. Our rigid docking experiments show that the GWO programs have enhanced exploration capability leading to significant speedup in the search while maintaining comparable binding pose prediction accuracy to AutoDock Vina. For flexible receptor docking, the GWO methods are competitive in pose ranking but lower in success rates than AutoDockFR. Successful redocking of all the flexible cases to their holo structures reveals that inaccurate scoring function and lack of proper treatment of backbone are the major causes of docking failures.


Author(s):  
Rajkumar Singh Rathore ◽  
Suman Sangwan ◽  
Shiv Prakash ◽  
Kabita Adhikari ◽  
Rupak Kharel ◽  
...  

2021 ◽  
Vol 239 ◽  
pp. 114231
Author(s):  
Ali Habibollahzade ◽  
Iman Fakhari ◽  
Saeed Mohsenian ◽  
Hossein Aberoumand ◽  
Robert A. Taylor

2021 ◽  
Vol 13 (6) ◽  
pp. 3314
Author(s):  
Rawan Shabbar ◽  
Anemone Kasasbeh ◽  
Mohamed M. Ahmed

Optimal placement of Charging stations (CSs) and infrastructure planning are one of the most critical challenges that face the Electric Vehicles (EV) industry nowadays. A variety of approaches have been proposed to address the problem of demand uncertainty versus the optimal number of CSs required to build the EV infrastructure. In this paper, a Markov-chain network model is designed to study the estimated demand on a CS by using the birth and death process model. An investigation on the desired number of electric sockets in each CS and the average number of electric vehicles in both queue and waiting times is presented. Furthermore, a CS allocation algorithm based on the Markov-chain model is proposed. Grey Wolf Optimization (GWO) algorithm is used to select the best CS locations with the objective of maximizing the net profit under both budget and routing constraints. Additionally, the model was applied to Washington D.C. transportation network. Experimental results have shown that to achieve the highest net profit, Level 2 chargers need to be installed in low demand areas of infrastructure implementation. On the other hand, Level 3 chargers attain higher net profit when the number of EVs increases in the transportation network or/and in locations with high charging demands.


Sign in / Sign up

Export Citation Format

Share Document