scholarly journals Structural and Pharmacological Properties of Alkaloids with Special Reference to Thebaine Type Alkaloids

2019 ◽  
Vol 17 (3) ◽  
Author(s):  
Sivakumar JT Gowder
Keyword(s):  
Special Reference ◽  
Pharmacological Properties

THE PHARMACOLOGY OF THE RAUWOLFIA ALKALOIDS CHANDRINE AND SERPAKRINE

1960 ◽  
Vol 38 (1) ◽  
pp. 889-897
Author(s):  
A. K. Reynolds ◽  
H. J. Presutti ◽  
D. P. MacLeod
Keyword(s):  
Smooth Muscle ◽  
Special Reference ◽  
Comparative Studies ◽  
Hypotensive Activity ◽  
Pharmacological Properties ◽  
Root Extracts ◽  
Cardiovascular Actions ◽  
Per Se ◽  
Ganglionic Blocking ◽  
Depressor Action

The pharmacological properties of two new alkaloids of Rauwolfia serpentina have been studied with special reference to their cardiovascular actions. In several instances, comparative studies have been carried out with the clinically used alseroxylon fraction of R. serpentina. Chandrine and serpakrine do not profoundly influence the activity or behavior of intact animals unless administered in very large doses. They are completely devoid of the tranquilizing action that characterizes such bases as reserpine and rescinnamine. They do, however, exhibit marked hypotensive activity. The mechanism of this depressor action has not been clearly established. It is not seen in spinal animals, and there is no evidence of ganglionic blocking or peripheral adrenolytic action. The effects of chandrine or serpakrine per se on smooth muscle structures are not pronounced, but antiacetylcholine activity has been observed on these and other preparations. Their contribution to the actions of the clinically employed whole-root extracts is probably not very marked.

scholarly journals A REVIEW ON PHARMACOLOGICAL PROPERTIES OF PANCH SAKAR CHURNA WITH SPECIAL REFERENCE TO ITS ROLE ON MALA BADDHATA

2018 ◽  
Vol 9 (2) ◽  
pp. 28-30
Author(s):  
Jyoti Rathi ◽  
Hemlata Harish Shende ◽  
Sameeksha Santosh Gurav ◽  
Santosh K Gurav
Keyword(s):  
Special Reference ◽  
Pharmacological Properties

scholarly journals An Appraisal of Vatsanābha (Aconitum Ferox Wall.) with Special Reference to Classical Texts Of Ayurveda: Saṁhitā, Cikitsā Grantha, Nighaṇṭus And Rasagrantha

The Healer ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 19-25
Author(s):  
Mital Buha ◽  
Niral Sojeetra ◽  
Rabinarayan Acharya
Keyword(s):  
Medicinal Plant ◽  
Special Reference ◽  
Morphological Characters ◽  
Pharmacological Properties ◽  
Purification Procedure ◽  
Base Metals ◽  
Single Drug ◽  
Cns Stimulation ◽  
Clinical Conditions ◽  
Collective Information

Background: Vatsanābha, (Aconitum ferox Wall., Ranunculaceae), has been well documented in Ayurvedic texts such as Saṁhitā (treatise), Nighaṇṭu (lexicons), Rasagranthas (compendia related to alchemy) and Cikitsā granthas (compendia of Ayurveda). Methods: This paper provides a collective information regarding Vatsanābha, its morphological characters, properties and actions mentioned in Nighantu, Samhita and Rasagrantha. Result and discussion: The study reveals that Vatsanābha, a medicinal plant has about forty-one synonyms (paryaya); and highlightes its morphological characters and pharmacological properties. It is attributed with properties like Vyavāyī (CNS stimulation followed by depression), Balya (tonic), Rasāyana (Rejuvenation), Kaṇṭharukhara (reliever of throat pain), etc. As a single drug, Vatsanābha is indicated in about twenty-seven clinical conditions like Agnimāndhya (digestive impairment), Kāsa (cough), Madāvaha (alcoholism), Gulma (abdominal lump), etc. Vatsanābha is used for Śodhana (purification procedure), krāmaṇa (transformation of base metals into gold) and Vedhana (alchemy); 3 saṅskāra among the aṣṭasaṅskāra of pārada. Conclusion: This review may enrich to documentary research and may provide collective and detailed information regarding Vatsanābha as it is presented in ayurvedic classical texts.

scholarly journals Study of Aragvadha (Cassia fistula Linn.) with special reference to phyto-pharmacological properties: An overview

2019 ◽  
Vol 20 (1&2) ◽  
pp. 133-138
Author(s):  
P. Chauhan ◽  
◽  
R. C., Tiwari ◽  
R. Bhutiani ◽  
F. Ahamad ◽  
...  
Keyword(s):  
Special Reference ◽  
Pharmacological Properties ◽  
Cassia Fistula

Concept of Shodhana procedure with special reference to Guggulu Resin (Commiphora Mukul Linn.)

2016 ◽  
Vol 1 (2) ◽  
Author(s):  
Dr.Pramod C. Baragi ◽  
Basavaraj M. S. ◽  
Praveen Simpi ◽  
Bandeppa Sangolge
Keyword(s):  
Special Reference ◽  
Therapeutic Effect ◽  
Pharmacological Properties ◽  
Single Drug ◽  
Commiphora Mukul ◽  
The Media ◽  
Vedic Period ◽  
Pharmaceutical Processes

Ayurveda, the science of life is being practiced by Aryans from Vedic period. In the Vedic period Guggulu was a well-known drug in Indigenous System of Medicine. In Atharvaveda it is mentioned to be used both externally and internally. By just consuming the odour of Guggulu, it reduces many diseases. Many properties of Guggulu are described in our classics. Guggulu is the oleoresin of Commiphora Mukul Linn., a plant that is native to India. Its extracts include compounds known for their hypolipidemic properties, the Z- and E- isomers of guggulsterone and its related guggulsterols. Kalpana is the process through which a substance can be transformed in to the form of medicine according to the need. During preparations of various formulations there are various Samskaras which are to be done for potentiating the drug or the formulation. Among all these pharmaceutical processes Shodhana is one of them. In our text, for a single drug many process of Shodhana in different ways have been mentioned. There are different medias explained in literature for Shodhana of Guggulu. According to the media of purification the quality and pharmacological properties of Guggulu will vary. Depending on the change in properties the therapeutic effect may also vary. The present study includes collection of different concepts regarding Shodana of Guggulu as per various classical references.

THE PHARMACOLOGY OF THE RAUWOLFIA ALKALOIDS CHANDRINE AND SERPAKRINE

1960 ◽  
Vol 38 (8) ◽  
pp. 889-897 ◽  
Author(s):  
A. K. Reynolds ◽  
H. J. Presutti ◽  
D. P. MacLeod
Keyword(s):  
Smooth Muscle ◽  
Special Reference ◽  
Comparative Studies ◽  
Hypotensive Activity ◽  
Pharmacological Properties ◽  
Root Extracts ◽  
Cardiovascular Actions ◽  
Per Se ◽  
Ganglionic Blocking ◽  
Depressor Action

The pharmacological properties of two new alkaloids of Rauwolfia serpentina have been studied with special reference to their cardiovascular actions. In several instances, comparative studies have been carried out with the clinically used alseroxylon fraction of R. serpentina. Chandrine and serpakrine do not profoundly influence the activity or behavior of intact animals unless administered in very large doses. They are completely devoid of the tranquilizing action that characterizes such bases as reserpine and rescinnamine. They do, however, exhibit marked hypotensive activity. The mechanism of this depressor action has not been clearly established. It is not seen in spinal animals, and there is no evidence of ganglionic blocking or peripheral adrenolytic action. The effects of chandrine or serpakrine per se on smooth muscle structures are not pronounced, but antiacetylcholine activity has been observed on these and other preparations. Their contribution to the actions of the clinically employed whole-root extracts is probably not very marked.

scholarly journals Activity of Selected Essential Oils against <i>Candida</i> spp. strains. Evaluation of New Aspects of their Specific Pharmacological Properties, with Special Reference to Lemon Balm

2013 ◽  
Vol 03 (04) ◽  
pp. 317-325 ◽  
Author(s):  
Aleksandra Budzyńska ◽  
Beata Sadowska ◽  
Grażyna Lipowczan ◽  
Agnieszka Maciąg ◽  
Danuta Kalemba ◽  
...  
Keyword(s):  
Essential Oils ◽  
Special Reference ◽  
Pharmacological Properties ◽  
Lemon Balm
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