scholarly journals Correlation between Central Corneal Thickness, Intraocular Pressure, Optic Disc Size and Cup-Disc Ratio in Normal Population

2017 ◽  
Vol 29 (20B) ◽  
Author(s):  
Mayuri Bakulesh Khamar ◽  
Parul Mehul Danayak ◽  
Hinal Patel
Keyword(s):  
Intraocular Pressure ◽  
Optic Disc ◽  
Central Corneal Thickness ◽  
Normal Population ◽  
Corneal Thickness ◽  
Optic Disc Size ◽  
Disc Size

Optic Disc Planimetry, Corneal Hysteresis, Central Corneal Thickness, and Intraocular Pressure as Risk Factors for Glaucoma

2014 ◽  
Vol 157 (2) ◽  
pp. 441-446 ◽  
Author(s):  
Francis Carbonaro ◽  
Pirro G. Hysi ◽  
Samantha J. Fahy ◽  
Abhishek Nag ◽  
Christopher J. Hammond
Keyword(s):  
Risk Factors ◽  
Intraocular Pressure ◽  
Optic Disc ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Corneal Hysteresis

scholarly journals Central corneal thickness and intraocular pressure in patients of primary open angle glaucoma and normal population in Nepalese population: A hospital based study

2019 ◽  
Vol 11 (1) ◽  
pp. 46-54
Author(s):  
Lalit Agarwal ◽  
Nisha Agrawal ◽  
Badri Prasad Badhu ◽  
Poonam Lavaju
Keyword(s):  
Intraocular Pressure ◽  
Central Corneal Thickness ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Normal Population ◽  
Corneal Thickness ◽  
Open Angle ◽  
Glaucomatous Damage ◽  
Significant Difference ◽  
Primary Glaucoma

Introduction: Central corneal thickness (CCT) is a powerful predictor of primary open angle glaucoma. Individualized risk assessment is critical for early diagnosis and management of glaucoma. Objectives: To compare CCT and intraocular pressure in patients of primary openangle glaucoma (POAG) with those of normal population. Materials and methods: A Comparative Cross-Sectional Study was performed in Ophthalmology department of B. P. Koirala Institute of Health Sciences, Nepal. Newly diagnosed cases of primary glaucoma (open angle, normal tension) of 18 years and above, without known systemic diseases were included. Results: Out of a total of 291 subjects (582 eyes), 105 subjects (210 eyes) were with primary glaucoma and 186 (382 eyes) were normal subjects. There was no significant difference in CCT between glaucomatous (533.57 μm) and normal (530.06 μm) eyes (p=0.1). Cornea was thinner (518.±18.03 μm) in eyes with severe glaucomatous damage (cup:disc ratio > 0.8) than in moderate glaucomatous damage (cup:disc ratio=0.5-0.8)(p=0.003). There was a statistically significant difference of 22.05 μm in CCT between POAG and NTG (p<0.001). A positive correlation was found between IOP & CCT in both cases and control group (p=0.000; r = 0.355, 0.254; r2 =0.126, 0.064 respectively). Conclusion: Majority of studied Nepalese population have CCT less than 550 μm, thus increasing the risk of POAG. CCT decreases with age, and females with glaucoma have significantly thicker cornea than men. There is a significant positive correlation between CCT and IOP, and IOP will have to be adjusted for CCT for proper diagnosis and monitoring of glaucomatous damage in Nepalese population too.  

Clinical Profile of Myopic Patients as a Risk Factor for Primary Open Angle Glaucoma - A Prospective Observational Study in Gorakhpur, Uttar Pradesh

2021 ◽  
Vol 8 (33) ◽  
pp. 3084-3089
Author(s):  
Ram Kumar Jaiswal ◽  
Ramyash Singh Yadav ◽  
Mridula Ranjan ◽  
Dipti Wahi ◽  
Chiranji Rai
Keyword(s):  
Risk Factor ◽  
Intraocular Pressure ◽  
Observational Study ◽  
High Myopia ◽  
Central Corneal Thickness ◽  
Prospective Observational Study ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Corneal Thickness ◽  
Open Angle

BACKGROUND Myopia is a complex trait including both genetic and environmental factors as well as gene-environment interactions. It has been recognized as a risk factor for development of glaucoma. Both Myopia and raised IOP are known to increase mechanical stress at optic nerve head leading to glaucomatous nerve damage. This study intends to evaluate the clinical profile of myopic subjects and its correlation with Primary open angle glaucoma (POAG). METHODS A prospective observational study done from November 2019 to December 2020 after taking proper informed consent and ethical clearance. 164 eyes of 96 patients studied were divided into three groups, Group 1: low myopia (< -3.00D), Group 2: moderate myopia (-3.00 D to -5.75 D), Group 3: high myopia (≥ -6.00 D). A complete ocular examination was performed. Intraocular pressure was measured using Goldmann applanation tonometer. Visual field analysis using Humphrey automated perimetry was done in patients with suspected primary open angle glaucoma (POAG). Angle parameters and central corneal thickness (CCT) were measured using anterior segment optical coherence tomography (AS-OCT). RESULTS 164 eyes of 96 Myopic subjects were studied with no dropout during study period. Mean age was 46.05 yr. (range: 25-75 yr.). The refraction ranged from -0.50 DS to -17.00 DS. There was no statistically significant difference between Intraocular pressure (IOP), Central corneal thickness (CCT), corrected IOP and Nasal and Temporal Trabecular-iris Angle (TIA) between male and female of same age group. Mean IOP and mean CCT were found to vary significantly with age and with higher degree of myopia. Corrected IOP, Nasal and Temporal TIA increase significantly with higher degree of myopia. Cup-disc ratio (CDR) was found to be significantly higher in patients with moderate to high degree of Myopia. CONCLUSIONS Myopia is an important risk factor for development of primary open angle glaucoma, with its incidence increasing in patients with moderate to high myopia. KEYWORDS Myopia, Primary Open Angle Glaucoma, Intraocular Pressure, Central Corneal Thickness, Trabecular Iris Angle

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