scholarly journals Meta-Analysis: Acupuncture Therapy in Reducing Blood Pressure on Hypertensive Patients

2020 ◽  
Author(s):  
Fahmi Eko Susilo ◽  
◽  
Hanung Prasetya ◽  
Agus Kristiyanto ◽  
◽  
...  
Keyword(s):  
Blood Pressure ◽  
Randomized Controlled Trial ◽  
Acupuncture Therapy ◽  
Controlled Trial ◽  
Meta Analysis ◽  
Blood Pressure Reduction ◽  
Reduce Blood Pressure ◽  
Sham Acupuncture ◽  
Hypertensive Patients ◽  
Randomized Controlled

Background: Blood pressure control is an important component of cardiovascular disease prevention. Despite the advances in the treatment of hypertension; effective management remains poor. Studies have shown that acupuncture facilitated a significant reduction in blood pressure. The purpose of this study was to examine the effectiveness of acupuncture therapy in reducing blood pressure on hypertensive patients. Subjects and Method: This was a meta-analysis and systematic review. The study was conducted by collected articles from PubMed, Google Schoolar, Mendeley, and Hindawi databases. Keywords used “acupuncture hypertension” OR “acupuncture high blood pressure” AND “efficacy acupuncture” AND “hypertension” AND “effect acupuncture for hypertension” AND “randomized controlled trial” AND “visual analogue scale”. The study population was patients with hypertension. The intervention was acupuncture. The comparison was sham acupuncture. The outcome was blood pressure reduction. The inclusion criteria were full text with English language and using randomized controlled trial study design. The selected articles were analyzed by PRISMA flow diagram and RevMan 5.3. Results: 7 articles were studied. There was high heterogeneity between experiment groups (I2= 66%; p= 0.007). Acupuncture therapy was more effective to reduce blood pressure than sham acupuncture (Standardized Mean Difference= 0.13; 95% CI= -0.13 to 0.39; p= 0.320). Conclusion: Acupuncture therapy is effective to reduce blood pressure in patients with hypertension. Keywords: hypertension, acupuncture Correspondence: Fahmi Eko Susilo. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 081393644991. DOI: https://doi.org/10.26911/the7thicph.05.53

Effects of n-3 fatty acid supplements on cardiometabolic profiles in hypertensive patients with abdominal obesity in Inner Mongolia: a randomized controlled trial

2019 ◽  
Vol 10 (3) ◽  
pp. 1661-1670 ◽  
Author(s):  
Bo Yang ◽  
Mei-qi Shi ◽  
Zi-hao Li ◽  
Lin Shi ◽  
Ai-min Wang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Randomized Controlled Trial ◽  
Fatty Acid ◽  
Inner Mongolia ◽  
Controlled Trial ◽  
Reduce Blood Pressure ◽  
Hypertensive Patients ◽  
Randomized Controlled ◽  
Drug Treatments

Daily supplementation with n-3 fatty acid (FA) has been believed to be an adjunct or alternative to drug treatments to reduce blood pressure (BP) and triglyceride (TG) levels in western patients with high risk of cardiovascular disease.

scholarly journals A Randomized Controlled Trial Study on Hypertension Reduction Based on Disease Control Priorities to Manage High Blood Pressure

2021 ◽  
Author(s):  
Subhana Akber Khan ◽  
Shahzad Ali Khan ◽  
Assad Hafeez ◽  
Arif Zaka
Keyword(s):  
Blood Pressure ◽  
Randomized Controlled Trial ◽  
High Blood Pressure ◽  
Controlled Trial ◽  
Blood Pressure Reduction ◽  
Intervention Group ◽  
Strict Adherence ◽  
Hypertensive Patients ◽  
Randomized Controlled ◽  
And Control

Abstract BackgroundOne of the global targets for non-communicable diseases is to reduce the prevalence of hypertension by 25% by year 2025. In Pakistan, prevalence of hypertension is reported to be 24.9% among males and in females the prevalence is 24.7%. The purpose of this study was to test the deliverability of a multicomponent based intervention for reduction of high blood pressure to recommended 140/90 mm of Hg and to test its effectiveness in control of hypertension among hypertensive patients.MethodsUsing a randomized controlled trial, double blinded study design, the intervention was pilot-tested for its appropriateness for implementation in hospital. The intervention was given to hypertensive patients in the intervention group. A total of 240 participants were screened and recruited into the trial after obtaining an informed consent. An ethical approval was sought from Health Services Academy. Data was collected from December 2019 to March 2020. All the data was entered and analyzed uing SPSS version 21.ResultsImplementation of a multi-component intervention to test DCP3 based strategies for management and control of hypertension in a hospital setting during three months yielded – 23.9 mm Hg of systolic blood pressure reduction (95% confidence interval, p ≤ 0.005). A significant reduction in the blood pressure to recommended target in intervention group was achieved in 6th, 8th and 12th week. As compared to patients in usual care group, improved health outcomes were achieved for diet control, reduction in salt intake and an increased physical exercise among hypertensive patients. Regular follow up and strict adherence to prescribed medicines was observed in both groups.ConclusionStudy findings concluded that the multicomponent intervention particlulary use of low salt and lifestyle modifications is effective in hypertension reduction. Involving family members of the patient was an essential component of non-pharmacologocal treatment which was found to be beneficial for management and control of hypertension.Trial registration: The study was registered in clinicaltrials.gov number NCT04336631 dated April 07, 2020.

Acupuncture Therapy in Reducing Pain in Patients with Low Back Pain: Meta Analysis

2020 ◽  
Author(s):  
Elisa Novitasari ◽  
◽  
RB. Soemanto ◽  
Hanung Prasetya ◽  
◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Low Back Pain ◽  
Back Pain ◽  
Acupuncture Therapy ◽  
Chronic Low Back Pain ◽  
Controlled Trial ◽  
Meta Analysis ◽  
Low Back ◽  
Randomized Controlled ◽  
Keywords Low Back Pain

ABSTRACT Background: With growing evidence of high prevalence in developing countries, LBP is no longer recognized as a disorder confined to high-income nations but is a major health problem globally. The functional limitations and consequent disability create a heavy economic burden on individuals and society. This study aimed to acupuncture therapy in reducing pain in patients with low back pain. Subjects and Method: A meta-analysis and systematic review was conducted by search published articles from PubMed, Google Schoolar, Mendeley, Hindawi, and Clinical key databases. Keywords used “acupuncture low back pain” OR “acupuncture chronic pain” AND “efficacy acupuncture” AND “chronic low back pain” AND “effect acupuncture for low back pain” AND “randomized controlled trial” AND “visual analogue scale”. The inclusion criteria were full text and using randomized controlled trial (RCT) study design. The articles were selected by PRISMA flow chart and the quantitative data were analyzed by Revman 5.3. Results: 7 studies were met criteria. This study showed that acupuncture therapy reduced pain in patients with low back pain (Mean Difference= -0.40; 95% CI= -0.80 to 0.01; p= 0.05) with heterogeneity I2= 83%. Conclusion: Acupuncture therapy reduces pain in patients with low back pain. Keywords: low back pain, acupuncture chronic low back pain, randomized controlled trial. Correspondence: Elisa Novitasari. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 085727851938. DOI: https://doi.org/10.26911/the7thicph.05.43

scholarly journals INTEnsive care bundle with blood pressure reduction in acute cerebral hemorrhage trial (INTERACT3): study protocol for a pragmatic stepped-wedge cluster-randomized controlled trial

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Lili Song ◽  
Xin Hu ◽  
Lu Ma ◽  
Xiaoying Chen ◽  
Menglu Ouyang ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Randomized Controlled Trial ◽  
Primary Outcome ◽  
Controlled Trial ◽  
Blood Pressure Reduction ◽  
Care Bundle ◽  
Pressure Reduction ◽  
Stepped Wedge ◽  
Randomized Controlled ◽  
Cluster Randomized

Abstract Background Early intensive blood pressure (BP) lowering remains the most promising treatment for acute intracerebral hemorrhage (ICH), despite discordant results between clinical trials and potential variation in the treatment effects by approach to control BP. As the third in a series of clinical trials on this topic, the INTEnsive care bundle with blood pressure Reduction in Acute Cerebral hemorrhage Trial (INTERACT3) aims to determine the effectiveness of a goal-directed care bundle protocol of early physiological control (intensive BP lowering, glycemic control, and pyrexia treatment) and reversal of anticoagulation, in acute ICH. Methods INTERACT3 is a pragmatic, international, multicenter, stepped-wedge (4 phases/3 steps), cluster-randomized controlled trial to determine the effectiveness of a multifaceted care package in adult (age ≥ 18 years) patients (target 8360) with acute ICH (< 6 h of onset) recruited from 110 hospitals (average of 19 consecutive patients per phase) in low- and middle-income countries. After a control phase, each hospital implements the intervention (intensive BP lowering, target systolic < 140 mmHg; glucose control, target 6.1–7.8 mmol/L and 7.8–10.0 mmol/L in those without and with diabetes mellitus, respectively; anti-pyrexia treatment to target body temperature ≤ 37.5 °C; and reversal of anticoagulation, target international normalized ratio < 1.5 within 1 h). Information will be obtained on demographic and baseline clinical characteristics, in-hospital management, and 7-day outcomes. Central trained blinded assessors will conduct telephone interviews to assess physical function and health-related quality of life at 6 months. The primary outcome is the modified Rankin scale (mRS) at 6 months analyzed using ordinal logistic regression. The sample size of 8360 subjects provides 90% power (α = 0.05) to detect a 5.6% absolute improvement (shift) in the primary outcome of the intervention versus control standard care, with various assumptions. Discussion As the largest clinical trial in acute ICH, INTERACT3 is on schedule to provide an assessment of the effectiveness of a widely applicable goal-directed care bundle for a serious condition in which a clearly proven treatment has yet to be established. Trial registration ClinicalTrials.gov NCT03209258. Registered on 1 July 2017. Chinese Trial Registry ChiCTR-IOC-17011787. Registered on 28 June 2017

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