scholarly journals Potential for Zika virus transmission through blood transfusion demonstrated during an outbreak in French Polynesia, November 2013 to February 2014

2014 ◽  
Vol 19 (14) ◽  
Author(s):  
D Musso ◽  
T Nhan ◽  
E Robin ◽  
C Roche ◽  
D Bierlaire ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Blood Transfusion ◽  
Zika Virus ◽  
Blood Donors ◽  
Blood Donation ◽  
Virus Transmission ◽  
French Polynesia ◽  
Nucleic Acid Testing ◽  
Blood Safety ◽  
Zika Fever

Since October 2013, French Polynesia has experienced the largest documented outbreak of Zika virus (ZIKAV) infection. To prevent transmission of ZIKAV by blood transfusion, specific nucleic acid testing of blood donors was implemented. From November 2013 to February 2014: 42 (3%) of 1,505 blood donors, although asymptomatic at the time of blood donation, were found positive for ZIKAV by PCR. Our results serve to alert blood safety authorities about the risk of post-transfusion Zika fever.

scholarly journals Prevention of transfusion-transmitted Zika virus in French Polynesia, nucleic acid testing versus pathogen inactivation

2016 ◽  
Vol 12 (1) ◽  
pp. 254-259 ◽  
Author(s):  
D. Musso ◽  
J. Broult ◽  
D. Bierlaire ◽  
M. C. Lanteri ◽  
M. Aubry
Keyword(s):  
Nucleic Acid ◽  
Zika Virus ◽  
French Polynesia ◽  
Nucleic Acid Testing ◽  
Pathogen Inactivation

scholarly journals Malaria Seroprevalence in the Blood Donors of Malaria Endemic Regions of Northern Andhra Pradesh, India.

2020 ◽  
Vol 6 (8) ◽  
pp. 493-497
Author(s):  
Dr. C. Sitalata ◽  
◽  
Dr. K. Kalyan ◽  
Keyword(s):  
Blood Transfusion ◽  
Andhra Pradesh ◽  
Blood Donors ◽  
Blood Donation ◽  
Transfusion Practice ◽  
Test Results ◽  
Blood Safety ◽  
Medical Sciences ◽  
Endemic Areas ◽  
Blood Bag

Introduction: Transmission of malaria through blood transfusion continues to be a major threat tosafe blood transfusion practice. Transfusion-transmitted malaria occurs at an estimated rate of 0.25cases per 1 million blood units collected. It is significantly more common in endemic areas. Aim: Tostudy the Seroprevalence of Malaria among the blood donors in the endemic areas of NorthernAndhra Pradesh. Materials and methods: The present survey was carried out at the blood bank ofMaharaja institute of medical sciences, Vizianagaram. This includes the analysis of seroprevalence ofMalaria in the blood donors during the period of 1 year from February 2018 to January 2019. Two mlof the blood sample was collected in the labeled pilot tube at the time of collection of blood fromdonor tubing of the blood bag. The serum was separated. The samples were tested for Malaria byrapid antigen detection test. Results: Out of the total of 3096 blood donors, replacement donors(86.91%) were more in comparison to voluntary donors (13.08%). The seroprevalence among thereplacement blood donors was more compared to voluntary blood donors. Conclusion: Voluntaryblood donation, increasing awareness about blood donation in the general population, selection ofrepeat, non-remunerated, regular voluntary blood donors and diligent donor selection, sensitivescreening tests are most important to increase blood safety and prevent transmission of Malariathrough blood transfusion.

scholarly journals The development of Legal Framework on blood donation and blood safety of China in 24 years

2020 ◽  
Author(s):  
Dajun Gao ◽  
Heng Li ◽  
Kang Wang
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Legal Framework ◽  
Nucleic Acid Amplification ◽  
Blood Collection ◽  
Chinese Government ◽  
Tort Liability ◽  
Blood Safety ◽  
Testing Technology

Abstract BackgroundThis study analyzes the regulations and developments in blood donation from 1996 to 2019 in China, and demonstrate the government’s efforts in improving blood safety.ResultsSince the implementation of the Blood Donation Law in 1998, the number of blood donors in China increased by 275% from 1998 to 2018 (from 4 million to 15 million). The principle of no-fault liability was proposed and has been applied since 2010 to the tort liability related to blood transfusion malpractice. In 2015, mutual blood donation accounts for 4.2% of the national collection. However, in some provinces of China, the percentage of mutual blood donation increased from 9.3% to 35.6% in 2016. The NHC cancelled mutual blood donation in March 2018. Nucleic acid amplification testing (NAT) has become a routine test item for screening blood since 2015.ConclusionsThe Chinese government institutionalized the voluntary non-remunerated donation principle, enacted regulations for the management of blood transfusion, and adopted advanced blood testing technology to sustain blood supply and ensure blood safety. In spited of increased blood donation, blood shortage persists. Quality and safety of blood collection can be further improved through the cancellation of mutual blood donation and incentive measures for voluntary non-remunerated donation of blood, which needs facilitation by governmental legislation.

scholarly journals The development of Legal Framework on blood donation and blood safety of China in 24 years

2020 ◽  
Author(s):  
Dajun Gao ◽  
Heng Li ◽  
Kang Wang
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Legal Framework ◽  
Nucleic Acid Amplification ◽  
Blood Collection ◽  
Chinese Government ◽  
Tort Liability ◽  
Blood Safety ◽  
Testing Technology

Abstract Background This study analyzes the regulation of and developments in blood donation in China from 1996 to 2019, and demonstrates the government’s efforts to improve blood safety.Results Since the implementation of the Blood Donation Law in 1998, the number of blood donors in China increased by 275% from 1998 to 2018 (from 4 million to 15 million). The principle of no-fault liability was proposed and has been applied since 2010 to the tort liability related to blood transfusion malpractice. In 2015, mutual blood donation accounted for 4.2% of the national collection. However, in some provinces of China, the percentage of mutual blood donation increased from 9.3% to 35.6% in 2016. The National Health Commission canceled mutual blood donation in March of 2018. Since 2015, nucleic acid amplification testing has become a routine test item for screening blood.Conclusions The Chinese government institutionalized the voluntary non-remunerated donation principle, enacted regulations for the management of blood transfusion, and adopted advanced blood testing technology to sustain blood supply and ensure blood safety. Despite increased blood donation, blood shortages persist. The quality and safety of blood collection can be further improved through the cancellation of mutual blood donation and incentive measures for voluntary non-remunerated donation of blood, which needs facilitation by governmental legislation.

scholarly journals The development of a legal framework for blood donation and blood safety in China over 24 years

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Dajun Gao ◽  
Heng Li ◽  
Kang Wang
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Legal Framework ◽  
Nucleic Acid Amplification ◽  
Blood Collection ◽  
Chinese Government ◽  
Tort Liability ◽  
Blood Safety ◽  
Testing Technology

Abstract Background This study analyzes the regulation of and developments in blood donation in China from 1996 to 2019, and demonstrates the government’s efforts to improve blood safety. Results Since the implementation of the Blood Donation Law in 1998, the number of blood donors in China increased by 275% from 1998 to 2018 (from 4 million to 15 million). The principle of no-fault liability was proposed and has been applied since 2010 to the tort liability related to blood transfusion malpractice. In 2015, mutual blood donation accounted for 4.2% of the national collection. However, in some provinces of China, the percentage of mutual blood donation increased from 9.3 to 35.6% in 2016. The National Health Commission canceled mutual blood donation in March of 2018. Since 2015, nucleic acid amplification testing has become a routine test item for screening blood. Conclusions The Chinese government institutionalized the voluntary non-remunerated donation principle, enacted regulations for the management of blood transfusion, and adopted advanced blood testing technology to sustain blood supply and ensure blood safety. Despite increased blood donation, blood shortages persist. The quality and safety of blood collection can be further improved through the cancellation of mutual blood donation and incentive measures for voluntary non-remunerated donation of blood, which needs facilitation by governmental legislation.

scholarly journals Blood Transfusion Service and Hospital Blood Rotation: The Implications on Transfusion Safety in Nigeria

2019 ◽  
Vol 2 (1) ◽  
pp. 19-24
Author(s):  
O D Damulak ◽  
E D Jatau ◽  
E Ekam ◽  
E Rumji ◽  
R Yakubu ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Diagnostic Test ◽  
Rapid Diagnostic Test ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Hospital ◽  
Sub Saharan Africa ◽  
High Rate ◽  
Blood Transfusion Service ◽  
First Time

Blood donation is not readily an altruistic sacrifice in sub-Saharan Africa where microbial infections, maternal haemorrhages, malaria and other tropical diseases that frequently require blood transfusion are daily diagnoses. Blood transfusion safety is hindered by the combined prevailing high rate of Transfusion-Transmissible Infections (TTIs) and poor screening techniques. This study determined the rate of Enzyme-Linked Immuno-Sorbent Assay (ELISA) positive reactions to transfusion-transmissible infections in rapid diagnostic test negative family replacement blood units, compared to the first time voluntarily donated blood. We studied records of blood units collected in a tertiary hospital from donors who scaled pre-donation Rapid diagnostic test (RDT) screening for the human immunodeficiency virus, hepatitis B and hepatitis C viruses and syphilis and rescreened by ELISA techniques at the National Blood Transfusion Service Centre in Jos, along with units from first-time voluntary blood donors. A total of 19562 blood units; 5945 (30.39%) rapid diagnostic tests negative from a linkage hospital and 13617 (69.61%) from first time voluntary donors were screened by ELISA methods for HIV, HBV, HCV, and syphilis. The overall TTIs detected by ELISA was 16.08%, significantly lower among pre-donation rapid screened family replacement blood donors [495(8.32%)] compared to 2651 (19.47%) among first-time voluntary donors; P=0.0001. Fifty-seven (0.96%) HIV, 166 (2.79%) HBV, 137 (2.31%) HCV and 137 (2.31%) syphilis were still detected respectively by ELISA in the pre-screened negative family replacement blood units. The outcome of ELISA screenings of blood collected from first-time volunteer donors were; 143 (1.05%) HIV, 1,486 (10.91%) HBV, 683 (5.02%) HCV, and 339 (2.49%) syphilis. Blood for transfusion should be screened negative at least with ELISA.

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