scholarly journals Malaria Seroprevalence in the Blood Donors of Malaria Endemic Regions of Northern Andhra Pradesh, India.

2020 ◽  
Vol 6 (8) ◽  
pp. 493-497
Author(s):  
Dr. C. Sitalata ◽  
◽  
Dr. K. Kalyan ◽  
Keyword(s):  
Blood Transfusion ◽  
Andhra Pradesh ◽  
Blood Donors ◽  
Blood Donation ◽  
Transfusion Practice ◽  
Test Results ◽  
Blood Safety ◽  
Medical Sciences ◽  
Endemic Areas ◽  
Blood Bag

Introduction: Transmission of malaria through blood transfusion continues to be a major threat tosafe blood transfusion practice. Transfusion-transmitted malaria occurs at an estimated rate of 0.25cases per 1 million blood units collected. It is significantly more common in endemic areas. Aim: Tostudy the Seroprevalence of Malaria among the blood donors in the endemic areas of NorthernAndhra Pradesh. Materials and methods: The present survey was carried out at the blood bank ofMaharaja institute of medical sciences, Vizianagaram. This includes the analysis of seroprevalence ofMalaria in the blood donors during the period of 1 year from February 2018 to January 2019. Two mlof the blood sample was collected in the labeled pilot tube at the time of collection of blood fromdonor tubing of the blood bag. The serum was separated. The samples were tested for Malaria byrapid antigen detection test. Results: Out of the total of 3096 blood donors, replacement donors(86.91%) were more in comparison to voluntary donors (13.08%). The seroprevalence among thereplacement blood donors was more compared to voluntary blood donors. Conclusion: Voluntaryblood donation, increasing awareness about blood donation in the general population, selection ofrepeat, non-remunerated, regular voluntary blood donors and diligent donor selection, sensitivescreening tests are most important to increase blood safety and prevent transmission of Malariathrough blood transfusion.

scholarly journals Potential for Zika virus transmission through blood transfusion demonstrated during an outbreak in French Polynesia, November 2013 to February 2014

2014 ◽  
Vol 19 (14) ◽  
Author(s):  
D Musso ◽  
T Nhan ◽  
E Robin ◽  
C Roche ◽  
D Bierlaire ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Blood Transfusion ◽  
Zika Virus ◽  
Blood Donors ◽  
Blood Donation ◽  
Virus Transmission ◽  
French Polynesia ◽  
Nucleic Acid Testing ◽  
Blood Safety ◽  
Zika Fever

Since October 2013, French Polynesia has experienced the largest documented outbreak of Zika virus (ZIKAV) infection. To prevent transmission of ZIKAV by blood transfusion, specific nucleic acid testing of blood donors was implemented. From November 2013 to February 2014: 42 (3%) of 1,505 blood donors, although asymptomatic at the time of blood donation, were found positive for ZIKAV by PCR. Our results serve to alert blood safety authorities about the risk of post-transfusion Zika fever.

scholarly journals Implementation of Data Mining to Predict The Feasibility of Blood Donors Using C4.5 Algorithm

2018 ◽  
Vol 1 (1) ◽  
pp. 41
Author(s):  
Anita Febriani ◽  
Tiara Trimadya Rahmawati ◽  
Eka Sabna
Keyword(s):  
Data Mining ◽  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Massive Data ◽  
Data Sets ◽  
Decision Tree Algorithm ◽  
C4.5 Algorithm ◽  
Blood Bag ◽  
A Company

Blood Transfusion Unit PMI Pekanbaru City is part of a company or agency that serves blood donation, every blood bag obtained from the community voluntarily come to PMI to donate blood with the goal of humanity. In Blood Transfusion Unit PMI Pekanbaru City, has provisions to be blood donors that must be met in order to donate blood in UTD PMI Pekanbaru City. Data Mining is a combination of a number of computer science disciplines that are defined as the process of discovering new patterns from massive data sets. By using RapidMiner software and using the method of Decision Tree Algorithm C4.5 to determine the eligibility of blood donors based on Age, Weight, Hemoglobin, and Blood Pressure. In the study of hemoglobin is the most decisive variable in blood donors. And the result accuracy is 94.02% which means the accuracy of this model is very good.

scholarly journals SERO-EPIDEMIOLOGICAL STUDY OF HEPATITIS B, C, HIV AND TREPONEMA PALLIDUM AMONG BLOOD DONORS IN HODEIDA CITY- YEMEN

2019 ◽  
Author(s):  
Ahmed Mohsen Al-kadassy ◽  
Abdulmalik Faisal Saleh Al-Ashiry ◽  
Hassan Abdulwahab Al-Shamahy
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Age Groups ◽  
Treponema Pallidum ◽  
Research Center ◽  
Age Group ◽  
Test Results ◽  
Current Prevalence

Infections transmitted in blood transfusions are the most significant concern associated with blood donation. The purpose of this study was to establish the current prevalence of hepatitis viruses (B and C), HIV and T.pallidium among blood donors at National Blood Transfusion and Research Center (NBTRC) Hodeida Branch, Hodeida city, Yemen. Serological markers of HBV, HCV, HIV 1, 2, T. pallidium antibodies were studied in 25446 (males) using commercially available kits, over a period of 3 years from January 2016 to April 2018 at National Blood Transfusion and Research Center (NBTRC) Hodeida Branch , Hodeida city, Yemen. Also, the prevalence of confirmed-positive test results of these infections was evaluated among different ages. The sero-prevalence of HBV and HCV, HIV, T. pallidium infections based on confirmation tests, were 0.74%, 0.19%, 0.38% and 0.18% respectively. The prevalence of HBV was significantly higher in age groups 37-46 years and 47-56 years with significant associated OR equal to 2.3 (p<0.001) and OR=2.7 (p=0.02) respectively. The prevalence of HCV was significantly higher in age groups 47-56 years with significant associated OR equal to 6.5 (p=0.003). The prevalence of T.pallidium was significantly higher in age group 37-46 years with significant associated OR equal to 3.6 (p<0.001). In conclusion: this study highlights the prevalence of HBV, HCV, HIV, and T. pallidium among different male ages. The prevalence varies from one age group to another, being the lowest among younger and very older age groups. Therefore, extensive recruitment of young donors should help ensure a long-term increase in the blood supply without jeopardizing safety.

scholarly journals The development of Legal Framework on blood donation and blood safety of China in 24 years

2020 ◽  
Author(s):  
Dajun Gao ◽  
Heng Li ◽  
Kang Wang
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Legal Framework ◽  
Nucleic Acid Amplification ◽  
Blood Collection ◽  
Chinese Government ◽  
Tort Liability ◽  
Blood Safety ◽  
Testing Technology

Abstract BackgroundThis study analyzes the regulations and developments in blood donation from 1996 to 2019 in China, and demonstrate the government’s efforts in improving blood safety.ResultsSince the implementation of the Blood Donation Law in 1998, the number of blood donors in China increased by 275% from 1998 to 2018 (from 4 million to 15 million). The principle of no-fault liability was proposed and has been applied since 2010 to the tort liability related to blood transfusion malpractice. In 2015, mutual blood donation accounts for 4.2% of the national collection. However, in some provinces of China, the percentage of mutual blood donation increased from 9.3% to 35.6% in 2016. The NHC cancelled mutual blood donation in March 2018. Nucleic acid amplification testing (NAT) has become a routine test item for screening blood since 2015.ConclusionsThe Chinese government institutionalized the voluntary non-remunerated donation principle, enacted regulations for the management of blood transfusion, and adopted advanced blood testing technology to sustain blood supply and ensure blood safety. In spited of increased blood donation, blood shortage persists. Quality and safety of blood collection can be further improved through the cancellation of mutual blood donation and incentive measures for voluntary non-remunerated donation of blood, which needs facilitation by governmental legislation.

scholarly journals The development of Legal Framework on blood donation and blood safety of China in 24 years

2020 ◽  
Author(s):  
Dajun Gao ◽  
Heng Li ◽  
Kang Wang
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Legal Framework ◽  
Nucleic Acid Amplification ◽  
Blood Collection ◽  
Chinese Government ◽  
Tort Liability ◽  
Blood Safety ◽  
Testing Technology

Abstract Background This study analyzes the regulation of and developments in blood donation in China from 1996 to 2019, and demonstrates the government’s efforts to improve blood safety.Results Since the implementation of the Blood Donation Law in 1998, the number of blood donors in China increased by 275% from 1998 to 2018 (from 4 million to 15 million). The principle of no-fault liability was proposed and has been applied since 2010 to the tort liability related to blood transfusion malpractice. In 2015, mutual blood donation accounted for 4.2% of the national collection. However, in some provinces of China, the percentage of mutual blood donation increased from 9.3% to 35.6% in 2016. The National Health Commission canceled mutual blood donation in March of 2018. Since 2015, nucleic acid amplification testing has become a routine test item for screening blood.Conclusions The Chinese government institutionalized the voluntary non-remunerated donation principle, enacted regulations for the management of blood transfusion, and adopted advanced blood testing technology to sustain blood supply and ensure blood safety. Despite increased blood donation, blood shortages persist. The quality and safety of blood collection can be further improved through the cancellation of mutual blood donation and incentive measures for voluntary non-remunerated donation of blood, which needs facilitation by governmental legislation.

scholarly journals The development of a legal framework for blood donation and blood safety in China over 24 years

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Dajun Gao ◽  
Heng Li ◽  
Kang Wang
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Legal Framework ◽  
Nucleic Acid Amplification ◽  
Blood Collection ◽  
Chinese Government ◽  
Tort Liability ◽  
Blood Safety ◽  
Testing Technology

Abstract Background This study analyzes the regulation of and developments in blood donation in China from 1996 to 2019, and demonstrates the government’s efforts to improve blood safety. Results Since the implementation of the Blood Donation Law in 1998, the number of blood donors in China increased by 275% from 1998 to 2018 (from 4 million to 15 million). The principle of no-fault liability was proposed and has been applied since 2010 to the tort liability related to blood transfusion malpractice. In 2015, mutual blood donation accounted for 4.2% of the national collection. However, in some provinces of China, the percentage of mutual blood donation increased from 9.3 to 35.6% in 2016. The National Health Commission canceled mutual blood donation in March of 2018. Since 2015, nucleic acid amplification testing has become a routine test item for screening blood. Conclusions The Chinese government institutionalized the voluntary non-remunerated donation principle, enacted regulations for the management of blood transfusion, and adopted advanced blood testing technology to sustain blood supply and ensure blood safety. Despite increased blood donation, blood shortages persist. The quality and safety of blood collection can be further improved through the cancellation of mutual blood donation and incentive measures for voluntary non-remunerated donation of blood, which needs facilitation by governmental legislation.

scholarly journals Blood Transfusion Service and Hospital Blood Rotation: The Implications on Transfusion Safety in Nigeria

2019 ◽  
Vol 2 (1) ◽  
pp. 19-24
Author(s):  
O D Damulak ◽  
E D Jatau ◽  
E Ekam ◽  
E Rumji ◽  
R Yakubu ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Diagnostic Test ◽  
Rapid Diagnostic Test ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Hospital ◽  
Sub Saharan Africa ◽  
High Rate ◽  
Blood Transfusion Service ◽  
First Time

Blood donation is not readily an altruistic sacrifice in sub-Saharan Africa where microbial infections, maternal haemorrhages, malaria and other tropical diseases that frequently require blood transfusion are daily diagnoses. Blood transfusion safety is hindered by the combined prevailing high rate of Transfusion-Transmissible Infections (TTIs) and poor screening techniques. This study determined the rate of Enzyme-Linked Immuno-Sorbent Assay (ELISA) positive reactions to transfusion-transmissible infections in rapid diagnostic test negative family replacement blood units, compared to the first time voluntarily donated blood. We studied records of blood units collected in a tertiary hospital from donors who scaled pre-donation Rapid diagnostic test (RDT) screening for the human immunodeficiency virus, hepatitis B and hepatitis C viruses and syphilis and rescreened by ELISA techniques at the National Blood Transfusion Service Centre in Jos, along with units from first-time voluntary blood donors. A total of 19562 blood units; 5945 (30.39%) rapid diagnostic tests negative from a linkage hospital and 13617 (69.61%) from first time voluntary donors were screened by ELISA methods for HIV, HBV, HCV, and syphilis. The overall TTIs detected by ELISA was 16.08%, significantly lower among pre-donation rapid screened family replacement blood donors [495(8.32%)] compared to 2651 (19.47%) among first-time voluntary donors; P=0.0001. Fifty-seven (0.96%) HIV, 166 (2.79%) HBV, 137 (2.31%) HCV and 137 (2.31%) syphilis were still detected respectively by ELISA in the pre-screened negative family replacement blood units. The outcome of ELISA screenings of blood collected from first-time volunteer donors were; 143 (1.05%) HIV, 1,486 (10.91%) HBV, 683 (5.02%) HCV, and 339 (2.49%) syphilis. Blood for transfusion should be screened negative at least with ELISA.

scholarly journals Prévalence de la syphilis chez les donneurs de sang à la Banque du Sang d’Abéché au Tchad

2020 ◽  
Vol 14 (3) ◽  
pp. 1085-1092
Author(s):  
Djamalladine Mahamat Doungous ◽  
Abdelsalam Adoum Doutoum ◽  
Adawaye Chatte ◽  
Richard Laougangta Dounbe ◽  
Elysée Gondimo Gabdibe ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Treponema Pallidum ◽  
Blood Bank ◽  
Sub Saharan Africa ◽  
Prise En Charge ◽  
Afrique Subsaharienne ◽  
Cross Sectional ◽  
Transfusion Sanguine

En Afrique subsaharienne, les infections transmissibles par la transfusion sanguine comme la syphilis sont très répandues, avec une prévalence pouvant atteindre 25% chez les donneurs de sang. La présente étude avait pour objectif de déterminer la prévalence de la syphilis chez les donneurs de sang au niveau de la Banque du Sang d’Abéché. Nous avons mené une étude transversale à visée descriptive, qui s’est déroulée de mai à août 2017. Les échantillons de sang des donneurs ont été testés par immunochromatographie pour la détection des anticorps anti-tréponémiques (Biomnis®). Sur 789 donneurs de sang inclus dans l’étude, la prévalence de la syphilis était de 4,9 %. Les donneurs étaient à 96,1% de sexe masculin et 3,9% de sexe féminin. Cette prévalence était plus élevée chez les sujets âgés de [21-30] ans, chez les femmes, les donneurs non scolarisés, divorcés et les domestiques/ménagères habitant la zone d’Abéché urbaine. Ces résultats montrent qu’il est nécessaire de mettre en place une politique de suivi et de prise en charge médicale des donneurs de sang atteints de la syphilis.Mots clés: Transfusion sanguine, receveurs, Treponema pallidum, don de sang.   English Title: Prevalence of syphilis in blood donors at Abéché blood bank in ChadIn sub-Saharan Africa, infections transmitted by blood transfusion such as syphilis are widespread, with prevalence up to 25% in blood donors. The purpose of this study was to determine the prevalence of syphilis in blood donors at the Blood Bank of Abéché. It was a descriptive cross-sectional study, which ran from May to August 2017. Donor blood samples were tested by immunochromatography for the detection of anti-treponemal antibodies (Biomnis®). Of the 789 blood donors included in the study, the prevalence of syphilis was 4.9%. Donors were 96.1% male and 3.9% female. This prevalence was higher in subjects aged [21-30] years, women, out-of-school, divorced and domestic / household donors living in the urban Abéché area. These results shows that it is necessary to set up a policy of monitoring and medical care of blood donors with syphilis.Keywords: Blood transfusion, recipients, Treponema pallidum, blood donation.

scholarly journals Patterns of voluntary and replacement blood donors in a tertiary care center: a retrospective study

2017 ◽  
Vol 5 (8) ◽  
pp. 3368
Author(s):  
P. K. Sehgal ◽  
Dinesh Garg
Keyword(s):  
Laboratory Tests ◽  
Blood Donors ◽  
Blood Donation ◽  
Care Center ◽  
Tertiary Care ◽  
Blood Safety ◽  
Female Adult ◽  
Bony Landmarks ◽  
Safe Blood ◽  
Donated Blood

Background: Blood donor base is the foundation of any blood transfusion system. In India any able-bodied individual between the age of 18 and 60 years can donate blood. Blood donors are of two types: voluntary donors and replacement donors. Blood donation should be done by low risk population otherwise there is high risk of transfusion transmissible infections like HIV, hepatitis B, hepatitis C and malaria. The present study was conceived to see the patterns of blood donation among voluntary and replacement blood donors in tertiary care centre.Methods: In this study 50 (27 male and 23 female) adult skulls were investigated to determine the type of asterion, its distance from important bony landmarks and also the nearby venous sinuses were measured.Results: Of the total 340078, 298421(87.75%) collections were voluntary and 41657(12.25%) were replacement collections. A total of 2810 camps were held to gather blood through voluntary donors. Number of blood camps held show an increasing pattern as we progress in time. Also, the trends in voluntary blood donations increased over the period and more donors donated blood whereas replacement donors decreased over the period and eventually vanished in time.Conclusions: For a safe blood service in our country, where comprehensive laboratory tests are neither possible nor pragmatic, it is best to switch over to 100% voluntary donations, as it is now established that only voluntary non-remunerated regular donation is the safest. Thus, one of our key strategies to enhance blood safety is to focus on motivating non-remunerated blood donors and phasing out even replacement donors.

scholarly journals A study to evaluate the demographic profile of voluntary and replacement blood donors at tertiary care hospital in Mumbai, India: a 5-year retrospective comparative analysis

2021 ◽  
Vol 9 (3) ◽  
pp. 866
Author(s):  
Khaneta Parveen ◽  
Abdul F. Khan ◽  
Abdul S. Khan
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Blood Donation ◽  
Tertiary Care ◽  
Care Hospital ◽  
Demographic Profile ◽  
Medical College ◽  
Donor Type ◽  
Males And Females ◽  
And Gender

Background: Blood donor base is the foundation of any blood transfusion system. Donor screening plays an important role in ensuring the safety of the blood supply.1 This study was undertaken with the aim to screen the blood donor’s demographic profile as male, female voluntary and replacement blood donors and to estimate seroprevalence of HIV, HBV, HCV and VDRL transmissible by blood transfusion in voluntary and replacement male and female blood donors during the last 5 year period.Methods: The present study was conducted over a period of 5 years (2001-2005) and involved 1,53,020 blood donors including both (voluntary, replacement males and females) who were thoroughly screened and selected for blood donation in blood bank at Departments of Pathology, Seth GS Medical College and KEM hospital, Mumbai. We determine among blood donors by their donor type (voluntary and replacement type) and gender wise.Results: The total number of blood donors in five years period was 1,53,020 (100%). Maximum number of voluntary  blood donors 1,00,316 (65.55%), followed by replacement blood donors 52,704 (34.33%).The overwhelming majority of donors in entire 5 years period was of male, comprising 1,36,195 (89.0%), while the female donors comprised of 16825 (10.99%).Conclusions: The maximum number of donors are voluntary males (55.69%) followed by replacement males (33.30%). Our results indicate that the number of female blood donors were less in comparison to male blood donors, so proper health education is required for female blood donors.

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