scholarly journals COVID19 infection revealed chronic myeloid leukemia in chronic phase: A case report

Author(s):  
Author(s):  

Treatment for Chronic myeloid leukemia has been revolutionized because of availability of different tyrosine kinase inhibitors. Each TKI come with its on toxicity profile as this needs to be taken in account before starting therapy with particular agent in a patient. Most of the adverse effects related to TKI are mild and can be managed by either symptomatic treatment or either by dose reduction. But some patients can become intolerant and to switch to other TKI remains the only option. Bosutinib is currently approved for treatment of chronic phase CML in patients who are either resistant or intolerant to previous TKI. We present a case of 59 year old male patient with CML who was intolerant to Dastanib and Nilotinib but showed excellent hematological and major molecular response to bosutinib


2011 ◽  
Vol 29 (2) ◽  
pp. 1102-1104
Author(s):  
Ou Ji ◽  
Qun Shen ◽  
Ya-Cheng Zhang ◽  
Jian-Min Ji ◽  
Guang-Rong Zhu ◽  
...  

Author(s):  
Abdullah Mohammad Arshad ◽  
mohamed yassin

Bosutinib is approved as first line therapy for treatment of chronic phase CML and also in patients who are either resistant or intolerant to previous TKI. We present a 59 year old male who was intolerant to 2 TKI but showed excellent hematological and major molecular response to Bosutinib.


2020 ◽  
Vol 8 (T1) ◽  
pp. 304-308
Author(s):  
Rasha Ibrahim ◽  
Georgios P. Chatzis ◽  
Mohamed A. Korayem ◽  
Mahmoud K. Mansour

Coronavirus disease-19 (COVID-19) is a pandemic viral disease that can cause devastating complications such as acute respiratory disease, especially in patients with comorbidities. We do not know yet full pictures of this disease, especially in hematological malignancies. Here, we present management of a 57-year-old male with chronic phase chronic myeloid leukemia, tested positive for COVID-19, then complicated with acute respiratory distress syndrome.


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