scholarly journals Differential Diagnosis of Malignant Melanoma and Benign Cutaneous Lesions by Ultrasound Analysis

2020 ◽  
Vol 2 (2) ◽  
pp. 100-107
Author(s):  
Michael Hambardzumyan ◽  
A. Hayrapetyan

Background:  The purpose of the study is to evaluate the assessment of ultrasound analysis in the differential diagnosis of skin melanoma and benign cutaneous lesions. Objective: 61 patients (23 men and 38 women) between 17 and 87 years of age, with melanomas, atheromas, hemangiomas, keratoses, and naevi were studied. Methods: High-frequency gray-scale ultrasound analysis, color Doppler, power Doppler, advanced dynamic flow, strain Elastography, digital Dermoscopy were performed in all cases. Results: In malignant melanoma cases we have mainly: sharp margins, hypoechoic, homogenous structure, absent of posterior shadowing, central and disorganized circulatory pattern with multiple peduncles. In some benign pathology, several ultrasound criteria were exclusive: microcalcifications are only in atheroma, posterior shadowing, and circular rim - in keratosis. The incidence of other ultrasound criteria can vary in atheroma, hemangioma, keratosis, and nevus. Tumor longitudinal and thickness relation were higher (7.9±1.96) than in all benign pathologies (2.1-4.8). The Elastography stiffness of the 26 skin melanomas was 2.95±0.18 and was higher than the group of 35 patients with all benign skin pathology (0.96±0.59), including atheroma (2.0±0.78), hemangioma (0.55±0.21), keratosis (1.21±0.21) and nevus (0.78±0.45). Conclusion: Multimodal approaches to exploring high-frequency ultrasound analytic criteria can be helpful in the differential diagnosis of malignant melanoma and benign cutaneous lesions.

2016 ◽  
Vol 91 (3) ◽  
pp. 262-273 ◽  
Author(s):  
Elisa de Oliveira Barcaui ◽  
Antonio Carlos Pires Carvalho ◽  
Flavia Paiva Proença Lobo Lopes ◽  
Juan Piñeiro-Maceira ◽  
Carlos Baptista Barcaui

2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Huitong Yan ◽  
Heying Li ◽  
Jianmei Han ◽  
Jianmei Han ◽  
Yingbo Tang

Objective: To investigate the ultrasonogram characteristics of common lumps in hand and foot, pursuing for greater understanding of hand and foot lumps. Methods: 65 cases of ultrasonographic characteristics of lumps in hand and foot were retrospectively analyzed, including the location, size, shape, boundary, internal echo and posterior echo, surrounding relationship and blood flow. Results: Among 65 cases, there were 26 cases of tendon sheath cyst, 16 cases of tenosynovitis giant cell tumor, 10 cases of hemangioma, 4 cases of tendon sheath fibroma, 3 cases of epidermoid cyst, 2 cases of Schwannoma, 2 cases of fibrolipoma, 1 case of angiolipoma and 1 case of neurofibroma. The preoperative and postoperative pathological diagnoses of 45 cases, accounting for 69.23%, were consistent, 3 cases (4.62%) were misdiagnosed, which included that 2 cases of tenosynovitis giant cell tumor were misdiagnosed as tendon sheath cyst, 1 case of neurofibroma as epidermoid cyst, and the preoperative diagnosis of the rest 17 cases(26.15%) were indefinite. Conclusion: The high-frequency ultrasound can diagnose properties of lumps in foot and hand well, providing diagnosis basis for further treatment in clinic.


Author(s):  
Aristida Colan-Georges

Objective: Despite the engineering progress, the diagnosis of breast cancer (BC) is unsatisfactory due to less specific descriptors and non-anatomical scanning and interpretation, proving that physicians lag behind technology. We aimed to improve the noninvasive positive and differential diagnosis of BC using modern technology applied to the new integrative concept of Full Breast Ultrasonography (FBU): anatomical radial scanning, color Doppler and Strain Sonoelastography (SE). Methods: We analyzed retrospectively 1841 consecutive FBUs in 1333 patients from screening, diagnosis, or follow-up, in two centers. We searched three descriptors: the ductal connection of the lesions, the incident angle of the plunging artery, and the SE (Ueno score). We compared the initial BI-RADS assessment with pathological reports or follow-up examinations of benign findings. Results: Radial scanning and ductal connection provided a standardized examination of the entire breast, with 100% sensitivity, early detection, precise location, and easy follow-up. We found no correlation BC-Density-Age, but a significant association BC - Benign pathology. The benign lesions, usually multiple, associated the proliferative and secretory types. The incident angle of the plunging artery was the best descriptor for the BC mass-type and associated with a score 4 or 5 Ueno led to PPV of 97.01%, specificity of 99.67%, and accuracy of 99.69%. Inflammatory BC illustrated high glandular strain and diffuse hyperemia. Conclusion: FBU had optimal accuracy, independent of the mammographic model, in screening and diagnosis. The vascular angle correlated with strain SE (adapted to the breast heterogeneity) raised the specificity and is recommended for inclusion in US BI-RADS.


Author(s):  
Nobuharu Hayashi ◽  
Yukio Miyamoto ◽  
Norio Nakata ◽  
Takeo Irie ◽  
Masahiro Ikegami ◽  
...  

2020 ◽  
Vol 10 (7) ◽  
pp. 1564-1569
Author(s):  
Hongzhu Wang ◽  
Da Yu ◽  
Kunzhong Bao

In order to investigate the characteristics of high-frequency ultrasound for the patients with thyroid nodules (TN), and we use the Thyroid Imaging Reporting And Data System (TI-RADS) to classify all the TN. Combined TIRADS classification with the features of color Doppler ultrasound and Doppler blood flow parameters for each nodule, we tried to diagnose TN between benign and malignant nodules so as to provide clinical physicians a more appropriate method and decision-making strategy for patients with of TN by ultrasound findings. The pulse Doppler technique was used to measure the peak systolic velocity (PSV) and resistance index (RI) of the blood flow within the nodule or closely around. The final pathology results were compared with all the ultrasound test. The diagnostic coincidence rates for B&M-TN were statistically compared by single two-dimensional ultrasound or by single color Doppler flow imaging or by combined technique of both. It can be seen that the combination strategy can optimize the coincidence rate of clinical diagnosis of B&M-TN. Therefore, the differential diagnosis of TN by high-frequency ultrasound TI-RADS classification combined with color Doppler blood flow parameters deserves our attention and further study.


2006 ◽  
Vol 17 (8) ◽  
pp. 2149-2159 ◽  
Author(s):  
D. -A. Clevert ◽  
T. Johnson ◽  
E. M. Jung ◽  
D. -A. Clevert ◽  
P. M. Flach ◽  
...  

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