scholarly journals Breast cancer and pyoderma gangrenosum: a complication after conservative surgery and radiotherapy

Mastology ◽  
2020 ◽  
Vol 30 ◽  
Author(s):  
Flávia Kuroda ◽  
Cicero Urban ◽  
Erica Mendes ◽  
Anelise Rocha Raymundo ◽  
Alessandra Amatuzzi Cordeiro Fornazari ◽  
...  

Pyoderma gangrenosum (PG) is a rare, ulcerative, and painful neutrophilic dermatosis of unknown cause associated with systemic diseases and/or pathergy phenomenon in 30% of cases. We report the case of a breast cancer patient submitted to oncoplastic conservative surgery followed by adjuvant radiotherapy, with long-term progression to PG. It’s rare and challeng ing nature reinforces the need for early diagnosis to increase treatment effectiveness and reduce morbidity.

2005 ◽  
Vol 41 (17) ◽  
pp. 2637-2644 ◽  
Author(s):  
A.C. Voogd ◽  
F.J. van Oost ◽  
E.J.T. Rutgers ◽  
P.H.M. Elkhuizen ◽  
A.N. van Geel ◽  
...  

2012 ◽  
Vol 14 (12) ◽  
pp. 953-960 ◽  
Author(s):  
Aurora Rodríguez Pérez ◽  
Maria Concepción López Carrizosa ◽  
Pilar Maria Samper Ots ◽  
José Fermín Pérez-Regadera Gómez ◽  
José Zapatero Ortuño ◽  
...  

2018 ◽  
Vol 16 (1) ◽  
pp. 66-69
Author(s):  
Smriti Shrestha ◽  
Alisha Aryal

Pyoderma gangrenosum is an uncommon neutrophilic dermatosis, seen on legs, and infrequently on hands and other anatomical sites. It is associated with systemic diseases in 50-70% of the cases. Antinuclear antibody (ANA) seropositivity has been reported in pyoderma gangrenosum associated with connective tissue disorders. However, there are very few case reports of pyoderma gangrenosum in patients of systemic lupus erythematosus, while we did not find any reports of ANA seropositivity in isolated pyoderma gangrenosum. Hence, we report this unique case of pyoderma gangrenosum with classical clinicohistopathology, positive ANA but no systemic association. As anticipated, our patient responded promptly to steroids.


2012 ◽  
Vol 55 (2) ◽  
pp. 283-288 ◽  
Author(s):  
Francesco Fiorica ◽  
Massimiliano Berretta ◽  
Stefano Ursino ◽  
Rossella Fisichella ◽  
Arben Lleshi ◽  
...  

1999 ◽  
Vol 15 (1-3) ◽  
pp. 207-211 ◽  
Author(s):  
P. Møller ◽  
G. Evans ◽  
N. Haites ◽  
H. Vasen ◽  
M. M. Reis ◽  
...  

Protocols for activity aiming at early diagnosis and treatment of inherited breast or breast-ovarian cancer have been reported. Available reports on outcome of such programmes are considered here. It is concluded that the ongoing activities should continue with minor modifications. Direct evidence of a survival benefit from breast and ovarian screening is not yet available. On the basis of expert opinion and preliminary results from intervention programmes indicating good detection rates for early breast cancers and 5-year survival concordant with early diagnosis, we propose that women at high risk for inherited breast cancer be offered genetic counselling, education in ‘breast awareness’ and annual mammography and clinical expert examination from around 30 years of age. Mammography every second year may be sufficient from 60 years on. BRCA1 mutation carriers may benefit from more frequent examinations and cancer risk may be reduced by oophorectomy before 40–50 years of age. We strongly advocate that all activities should be organized as multicentre studies subjected to continuous evaluation to measure the effects of the interventions on long-term mortality, to match management options more precisely to individual risks and to prepare the ground for studies on chemoprevention.


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