Determination of genotoxic impurities in pharmaceutical substances

Olga Vyacheslavovna Ananyina; Mikhail Dmitrievich Khorolsky; Galina Vladislavovna Ramenskaya; Evgeniy Andreevich Zhukov; Natalia Viktorovna Maslennikova

doi:10.29296/25419218-2020-07-02

Determination of genotoxic impurities in pharmaceutical substances

Farmaciya (Pharmacy) ◽

10.29296/25419218-2020-07-02 ◽

2020 ◽

Vol 69 (7) ◽

pp. 10-16

Author(s):

Olga Vyacheslavovna Ananyina ◽

Mikhail Dmitrievich Khorolsky ◽

Galina Vladislavovna Ramenskaya ◽

Evgeniy Andreevich Zhukov ◽

Natalia Viktorovna Maslennikova

Keyword(s):

Pharmaceutical Substances ◽

Genotoxic Impurities

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Sensitive derivatization methods for the determination of genotoxic impurities in drug substances using hyphenated techniques

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2013.11.013 ◽

2014 ◽

Vol 89 ◽

pp. 276-281 ◽

Cited By ~ 8

Author(s):

Nanduri V.V.S.S. Raman ◽

Adapa V.S.S. Prasad ◽

Kura Ratnakar Reddy

Keyword(s):

Hyphenated Techniques ◽

Drug Substances ◽

Genotoxic Impurities

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PURITY DETERMINATION OF THE STARTING MATERIALS USED IN THE SYNTHESIS OF PHARMACEUTICAL SUBSTANCES

Acta Poloniae Pharmaceutica - Drug Research ◽

10.32383/appdr/94437 ◽

2019 ◽

Vol 76 (1) ◽

pp. 29-35

Author(s):

Aleksandra Groman ◽

Elżbieta Stolarczyk ◽

Mariola Mucha

Keyword(s):

Purity Determination ◽

Pharmaceutical Substances ◽

Materials Used

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Simultaneous Trace Level Determination of Potentially Genotoxic Hydrazine, Methylhydrazine and Alkylamines in Pharmaceutical Substances by CE Using Indirect Photometric Detection

Chromatographia ◽

10.1007/s10337-013-2467-x ◽

2013 ◽

Vol 76 (13-14) ◽

pp. 801-809 ◽

Cited By ~ 10

Author(s):

Muzaffar Khan ◽

Shyam Kumar ◽

K. Jayasree ◽

K. V. S. R. Krishna Reddy ◽

P. K. Dubey

Keyword(s):

Trace Level ◽

Indirect Photometric Detection ◽

Photometric Detection ◽

Pharmaceutical Substances ◽

Trace Level Determination

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A practical derivatization LC/MS approach for determination of trace level alkyl sulfonates and dialkyl sulfates genotoxic impurities in drug substances

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2008.06.019 ◽

2008 ◽

Vol 48 (3) ◽

pp. 1006-1010 ◽

Cited By ~ 59

Author(s):

Jianguo An ◽

Mingjiang Sun ◽

Lin Bai ◽

Ted Chen ◽

David Q. Liu ◽

...

Keyword(s):

Trace Level ◽

Alkyl Sulfonates ◽

Drug Substances ◽

Genotoxic Impurities

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Trace Level Determination of Three Genotoxic Impurities in Drug Samples of Rizatriptan Benzoate by Liquid Chromatography-Tandem Mass Spectrometry

Analytical Chemistry Letters ◽

10.1080/22297928.2017.1322534 ◽

2017 ◽

Vol 7 (2) ◽

pp. 248-260 ◽

Cited By ~ 1

Author(s):

L. Narasimha Rao K ◽

N. Devanna ◽

K.V.N. Suresh Reddy

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass ◽

Trace Level ◽

Rizatriptan Benzoate ◽

Chromatography Tandem Mass Spectrometry ◽

Genotoxic Impurities ◽

Liquid Chromatography Tandem Mass ◽

Trace Level Determination

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Identification, control strategies, and analytical approaches for the determination of potential genotoxic impurities in pharmaceuticals: A comprehensive review

Journal of Separation Science ◽

10.1002/jssc.201401143 ◽

2015 ◽

Vol 38 (5) ◽

pp. 764-779 ◽

Cited By ~ 32

Author(s):

Ambavaram Vijaya Bhaskar Reddy ◽

Jafariah Jaafar ◽

Khalid Umar ◽

Zaiton Abdul Majid ◽

Azmi Bin Aris ◽

...

Keyword(s):

Control Strategies ◽

Comprehensive Review ◽

Genotoxic Impurities ◽

Analytical Approaches

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Utilization of Photochemically Induced Fluorescence Detection for HPLC Determination of Genotoxic Impurities in the Vortioxetine Manufacturing Process

Journal of Chromatographic Science ◽

10.1093/chromsci/bmw116 ◽

2016 ◽

Vol 54 (9) ◽

pp. 1625-1630 ◽

Cited By ~ 6

Author(s):

Michal Douša ◽

Jan Doubský ◽

Jan Srbek

Keyword(s):

Fluorescence Detection ◽

Manufacturing Process ◽

Hplc Determination ◽

Photochemically Induced Fluorescence ◽

Genotoxic Impurities

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Development of chromatographic methods for the determination of genotoxic impurities in cloperastine fendizoate

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2011.12.014 ◽

2012 ◽

Vol 61 ◽

pp. 230-236 ◽

Cited By ~ 13

Author(s):

Antonia García ◽

Francisco J. Rupérez ◽

Florencia Ceppa ◽

Federica Pellati ◽

Coral Barbas

Keyword(s):

Chromatographic Methods ◽

Genotoxic Impurities

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Simultaneous Determination of Genotoxic Impurities in Fudosteine Drugs by GC–MS

Journal of Chromatographic Science ◽

10.1093/chromsci/bmw070 ◽

2016 ◽

Vol 54 (8) ◽

pp. 1277-1281 ◽

Cited By ~ 1

Author(s):

Amarnatha Reddy Gooty ◽

Hussain Reddy Katreddi ◽

Raghavender Reddy S ◽

Raveendra K. Hunnur ◽

Hemant Kumar Sharma ◽

...

Keyword(s):

Simultaneous Determination ◽

Genotoxic Impurities

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Polymeric membrane ion-selective electrode for determination of bismuth (III) in pharmaceutical substances

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/s0731-7085(02)00122-x ◽

2002 ◽

Vol 30 (2) ◽

pp. 181-187 ◽

Cited By ~ 13

Author(s):

Sergey V Kharitonov

Keyword(s):

Ion Selective Electrode ◽

Polymeric Membrane ◽

Selective Electrode ◽

Pharmaceutical Substances

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