scholarly journals Anaplastic carcinoma with osteoclast-like giant cells: A case report

Suizo ◽  
2019 ◽  
Vol 34 (2) ◽  
pp. 114-121
Author(s):  
Hiroto FUJISAKI ◽  
Norihiro KISHIDA ◽  
Kaou MATSUDA ◽  
Yasuhiro ITO ◽  
Takayuki TAKAHASHI ◽  
...  
Suizo ◽  
2008 ◽  
Vol 23 (4) ◽  
pp. 501-509 ◽  
Author(s):  
Hiromichi ISHII ◽  
Atsuyuki MAEDA ◽  
Kazuya MATSUNAGA ◽  
Hideyuki KANEMOTO ◽  
Yukiyasu OKAMURA ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
pp. 1687-1690
Author(s):  
Lakshmi Priya Unnikrishnan ◽  
Noushad Babu PK ◽  
Asiq Sideeque

Undifferentiated carcinoma of pancreas with osteoclastic giant cells is a rare tumor. The prognosis is slightly better than usual anaplastic carcinoma. It is said to have an epithelial origin. We present a case of 61-year-old female who presented with features of cholangitis and on evaluation found to have pancreatic mass. Pancreatic intraepithelial neoplasia was also present in our case, which is a feature less commonly noted in published literature.


Pancreas ◽  
2009 ◽  
Vol 38 (5) ◽  
pp. 488-489
Author(s):  
Hiromichi Ishii ◽  
Atsuyuki Maeda ◽  
Kazuya Matsunaga ◽  
Hideyuki Kanemoto ◽  
Yukiyasu Okamura ◽  
...  

2016 ◽  
Vol 6 (12) ◽  
pp. 1048-1050
Author(s):  
S Karki ◽  
D Karki

Tuberculosis of the oral cavity which is an uncommon occurrence can be primary or secondary. In the absence of active pulmonary tuberculosis, isolated tonsillar tuberculosis is rare. Herein, we report two cases of bilateral tonsillar tuberculosis who presented as recurrent sore throat for which tonsillectomy was done. No active primary pulmonary lesion was found in these cases. Histopathological examination revealed caseating epithelioid granulomas with Langhans giant cells. Ziehl Neelson stain for acid fast bacilli was positive in one case. Tonsillar tuberculosis, though a rare entity, should be considered in the clinical differential diagnosis of tonsillar lesions. Histopathological examination with Ziehl Neelson stain should be performed for definite diagnosis.


2018 ◽  
Vol 13 (1) ◽  
Author(s):  
Lourdes Peña-Jaimes ◽  
Irene González-García ◽  
María Eugenia Reguero-Callejas ◽  
Ignacio Pinilla-Pagnon ◽  
Belén Pérez-Mies ◽  
...  

2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S42-S42
Author(s):  
A K Abu-Salah ◽  
S Segura ◽  
H Mesa ◽  
H M Cramer

Abstract Introduction/Objective Thyroid carcinoma showing thymus-like differentiation also known as intrathyroidal thymic carcinoma is a rare thyroid neoplasm arising from either an ectopic intrathyroidal thymic tissue or from remnants of thymobranchial pouches. On fine needle aspiration (FNA) its diagnosis can be challenging due to overlapping morphologic features with other aggressive thyroid carcinomas. Methods/Case Report A 31-year-old female consulted for 6-month history of neck swelling and tenderness. Thyroid ultrasound demonstrated a 2.6 x 2.5 x 2.1 cm nodule in the right lobe with punctate calcifications. FNA showed cellular smears composed of loosely cohesive and single basaloid neoplastic cells exhibiting significant cellular and nuclear pleomorphism. Focal squamous differentiation with keratinization was noted on the cell block sections. Immunocytochemical stains showed that the tumor was positive for cytokeratin AE1/AE3, p40, p63, CD117 and CD5 consistent with intrathyroidal thymic carcinoma. The Ki67 proliferative index was approximately 40%. A right thyroidectomy with central neck dissection confirmed the diagnosis and showed a 3.0 cm tumor with invasion into skeletal muscle, lymphovascular invasion and positive lymph nodes. The patient completed adjuvant radiotherapy and remain in remission at 3-months follow-up. Results (if a Case Study enter NA) NA Conclusion Intrathyroidal thymic carcinoma is a rare thyroid neoplasm that frequently shows squamous differentiation and therefore overlaps with papillary thyroid carcinoma with squamous morulae, squamous cell carcinoma and anaplastic carcinoma. The coexpression of squamous markers together with CD5 and CD117 allows the recognition of CASTLE on FNA samples.


2020 ◽  
Vol 4 (1) ◽  
pp. 29-32
Author(s):  
B. Sigdel ◽  
T. Dubey ◽  
Neeraj KC ◽  
R. Nepali ◽  
R. Maharjan ◽  
...  

Female, 66 years old with a chief complain of shortness of breath and lump over her neck since 6 month. Neck USG showed enlarged right lobe of thyroid gland with hyperechoic nodules. FNAC confirmed anaplastic carcinoma of thyroid. patient underwent chemotherapy using doxorubicin as agent of choice. She had difficulty in breathing and she kept on high flow of oxygen, even after she had stridor and planned for tracheostomy. MRI revealed heterogeneously enhancing mass (9.6*6.5*10.5 cm) replacing right lobe of thyroid, and extending superiorly till the level carotid bifurcation and inferiorly superior mediastinum. Lesion is partially encasing trachea and laryngeal airway, posteriorly extending into prevertebral space and anteriorly invading strap muscles and sternocleidomastoid muscle. Now it become very difficult stage. She transfers to ICU. intubation tried but failed. As mass was just anterior to trachea and difficult to do tracheostomy without intubation. all hope failed and she put continue to high flow of oxygen.  


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