scholarly journals Histopathologic Evaluation of The Phyllodes Tumor

2017 ◽  
Author(s):  
Lokot Donna Lubis
Keyword(s):  
Phyllodes Tumor ◽  
Histopathologic Evaluation

Histopathologic evaluation of the intraoperative specimens of the entire aorta

2010 ◽  
Vol 58 (S 01) ◽  
Author(s):  
A Juraszek ◽  
G Bayer ◽  
T Dziodzio ◽  
J Holfeld ◽  
J Dumfarth ◽  
...  
Keyword(s):  
Histopathologic Evaluation

A Case of Giant Phyllodes Tumor of the Breast

2013 ◽  
Vol 75 (6) ◽  
pp. 514-517
Author(s):  
Yuka NAKAMURA ◽  
Makoto ICHIMIYA ◽  
Kei NEMOTO ◽  
Yoshitaka NAKAMURA ◽  
Michiya YAMAGUCHI ◽  
...  
Keyword(s):  
Phyllodes Tumor

Giant phyllodes tumor of the breast

2019 ◽  
Vol 1 (23) ◽  
pp. 20
Author(s):  
Anca Zgură ◽  
Laurenţia Galeş ◽  
Elvira Brătilă ◽  
Rodica ANGHEL
Keyword(s):  
Phyllodes Tumor

scholarly journals Bilateral Phyllodes Giant Tumor. A Case Report Analyzed by Array-CGH

Diagnostics ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 825
Author(s):  
Francesco Fortarezza ◽  
Federica Pezzuto ◽  
Gerardo Cazzato ◽  
Clelia Punzo ◽  
Antonio d’Amati ◽  
...  
Keyword(s):  
Array Cgh ◽  
Phyllodes Tumor ◽  
Molecular Classification ◽  
Left Breast ◽  
Comparative Genomic ◽  
Fish Analysis ◽  
Molecular Tests ◽  
Giant Tumor ◽  
Metastatic Risk ◽  
The Right

The breast phyllodes tumor is a biphasic tumor that accounts for less than of 1% of all breast neoplasms. It is classified as benign, borderline, or malignant, and can mimic benign masses. Some recurrent alterations have been identified. However, a precise molecular classification of these tumors has not yet been established. Herein, we describe a case of a 43-year-old woman that was admitted to the emergency room for a significant bleeding from the breast skin. A voluminous ulcerative mass of the left breast and multiple nodules with micro-calcifications on the right side were detected at a physical examination. A left total mastectomy and a nodulectomy of the right breast was performed. The histological diagnosis of the surgical specimens reported a bilateral giant phyllodes tumor, showing malignant features on the left and borderline characteristics associated with a fibroadenoma on the right. A further molecular analysis was carried out by an array-Comparative Genomic Hybridization (CGH) to characterize copy-number alterations. Many losses were detected in the malignant mass, involving several tumor suppressor genes. These findings could explain the malignant growth and the metastatic risk. In our study, genomic profiling by an array-CGH revealed a greater chromosomal instability in the borderline mass (40 total defects) than in the malignant (19 total defects) giant phyllodes tumor, reflecting the tumor heterogeneity. Should our results be confirmed with more sensitive and specific molecular tests (DNA sequencing and FISH analysis), they could allow a better selection of patients with adverse pathological features, thus optimizing and improving patient’s management.

Phyllodes tumor of the breast clinical experience and outcomes: A retrospective cohort tertiary hospital experience

2021 ◽  
Vol 51 ◽  
pp. 151702
Author(s):  
Abdulmohsen Alkushi ◽  
Haitham Arabi ◽  
Lolwah Al-Riyees ◽  
Abdulelah M. Aldakheel ◽  
Raed Al Zarah ◽  
...  
Keyword(s):  
Clinical Experience ◽  
Retrospective Cohort ◽  
Phyllodes Tumor ◽  
Tertiary Hospital ◽  
Hospital Experience

Serum haptoglobin concentrations in feline inflammatory bowel disease and small-cell alimentary lymphoma: a potential biomarker for feline chronic enteropathies

2021 ◽  
pp. 1098612X2199144
Author(s):  
Edwina K Love ◽  
Nicole F Leibman ◽  
Randy Ringold ◽  
Kenneth Lamb
Keyword(s):  
Inflammatory Bowel Disease ◽  
Inflammatory Disease ◽  
Bowel Disease ◽  
Prognostic Significance ◽  
Small Cell ◽  
Clinically Normal ◽  
Serum Haptoglobin ◽  
Potential Biomarker ◽  
Histopathologic Evaluation ◽  
Inflammatory Bowel

Objectives The aim of this study was to evaluate serum haptoglobin as a biomarker to differentiate between small-cell alimentary lymphoma and inflammatory bowel disease in cats. Methods Client-owned domestic cats with and without chronic gastrointestinal signs were enrolled in the study. Serum was collected from each patient and serum haptoglobin levels were measured using ELISA. In cats with gastrointestinal signs, histopathologic evaluation of endoscopic biopsies harvested from the intestinal tract was used to separate them into inflammatory bowel disease and small-cell lymphoma cohorts. Serum haptoglobin levels were statistically analyzed and compared among the three groups: healthy cats; cats with inflammatory bowel disease; and cats with small-cell alimentary lymphoma. Results Sixty-two cats were enrolled in the study, including 20 clinically normal cats, 14 cats with small-cell alimentary lymphoma and 28 cats with inflammatory bowel disease. The mean ± SD serum haptoglobin was 73.2 ± 39.1 mg/dl in normal cats, 115.3 ± 72.8 mg/dl in cats with inflammatory bowel disease and 133.1 ± 86.1 mg/dl in cats with small-cell alimentary lymphoma. Cats with inflammatory bowel disease and lymphoma had significantly higher serum haptoglobin than controls, with P values of 0.0382 and 0.0138, respectively. There was no statistical difference between the inflammatory bowel disease and lymphoma cohorts ( P = 0.4235). For every one unit increase in serum haptoglobin, the odds of gastrointestinal inflammatory disease (inflammatory bowel disease or small-cell alimentary lymphoma) increased by 1.41% ( P = 0.0165). Conclusions and relevance Serum haptoglobin is a useful biomarker for distinguishing between normal cats and those with gastrointestinal inflammatory disease, but it could not significantly differentiate between inflammatory bowel disease and lymphoma. Additional studies may be beneficial in determining the prognostic significance of serum haptoglobin as it may relate to the severity of gastrointestinal inflammation.

scholarly journals Histopathologic Evaluation of COVID-19 Patients with Peripheral Arterial Thromboembolism: Does clot composition make any sense?

2021 ◽  
Author(s):  
Nihan Yesilkaya ◽  
Tahsin Murat Tellioglu ◽  
Fulya Cakalagaoglu Unay ◽  
Hasan İner ◽  
Yuksel Besir ◽  
...  
Keyword(s):  
Arterial Thromboembolism ◽  
Histopathologic Evaluation ◽  
Peripheral Arterial
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