scholarly journals Results of surgical resection of primary lung cancer

1989 ◽  
Vol 3 (4) ◽  
pp. 396-401
Author(s):  
Yoshiaki Abe ◽  
Hirokuni Yoshimura ◽  
Saburo Hirai ◽  
Jun Shinada ◽  
Akira Ishihara ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Surgical Resection ◽  
Primary Lung Cancer

Results of surgical resection of patients with primary lung cancer: a retrospective analysis of 1,905 cases

2001 ◽  
Vol 72 (4) ◽  
pp. 1155-1159 ◽  
Author(s):  
Dekang Fang ◽  
Dawei Zhang ◽  
Guojun Huang ◽  
Rugang Zhang ◽  
Liangjun Wang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Retrospective Analysis ◽  
Surgical Resection ◽  
Primary Lung Cancer

Risk factors associated with a second primary lung cancer (SPLC) in patients (pts) with a previous initial primary lung cancer (IPLC).

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e13166-e13166
Author(s):  
Misako Nagasaka ◽  
Dina Farhat ◽  
Kimberly Belzer ◽  
Seongho Kim ◽  
Hirva Mamdani ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lung Cancer ◽  
Family History ◽  
Surgical Resection ◽  
Tobacco Use ◽  
Primary Lung Cancer ◽  
Smoking History ◽  
Factors Associated ◽  
Increased Risk ◽  
First Diagnosis

e13166 Background: The risk for development of a SPLC after treatment of an IPLC is around 1% to 2% per pt per year. The aim of this study was to characterize the risk factors associated with the development of a SPLC. Methods: Pts registered in the Karmanos Cancer Institute Tumor Registry diagnosed with an IPLC between 2000 and 2017 were included in this study. Pts with an IPLC who later developed a SPLC were matched for age, histology and stage to pts with an IPLC who did not develop a SPLC. SPLC was defined as a second lung cancer with a different pathology or if the same pathology, anatomically, molecularly, or chronologically distinct. Six variables including: stage at IPLC, histology, family history, surgery as a primary treatment for IPLC, and smoking history (determined by pack years, and continued tobacco use after first diagnosis) were reviewed. Logistic and Cox regression analyses were performed to determine the relationship of these characteristics with the development of a SPLC, and their association with overall survival (OS). Results: 121 pts with IPLC who later developed an SPLC were identified and compared to 120 pts with IPLC who did not develop a SPLC. Logistic analyses did not show that stage at first diagnosis, histology, family history, smoking history, and continued tobacco use after first diagnosis to be relevant for increased risk of SPLC. Pts who were primarily treated with surgical resection had a significantly higher probability of developing a SPLC (Odds Ratio: 0.24, 95% CI: 0.12 to 0.48, p < 0.001). Pts who did not have surgical resection as their primary mode of treatment for IPLC had a significantly higher risk of death than those who received surgical resection (HR 3.02, 95% CI: 1.99 to 4.57; p < 0.001). Conclusions: Based on our findings, pts who had surgical resection for an IPLC were found to have improved OS and a higher possibility of developing a SPLC. Stage at first diagnosis of IPLC, histology, family history, smoking history and continued use of tobacco after first diagnosis did not correlate with increased risk for SPLC. These results warrant further investigation and if confirmed could have an impact on surveillance recommendations post resection of initial lung cancers.

scholarly journals P3.04-046 Cases of Surgical Resection of Post-Operative Lymph Node Recurrences from Primary Lung Cancer

2017 ◽  
Vol 12 (1) ◽  
pp. S1411-S1412
Author(s):  
Ema Mitsui ◽  
Masafumi Kataoka ◽  
Daisuke Okutani ◽  
Haruyuki Kawai ◽  
Kazuhiko Watanabe ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Surgical Resection ◽  
Primary Lung Cancer

scholarly journals Routine follow-up after surgical treatment of lung cancer: is chest CT useful?

2021 ◽  
pp. e20210025 ◽  
Author(s):  
Juliana B F Morellato1 ◽  
Marcos D Guimarães2 ◽  
Maria L L Medeiros1 ◽  
Hélio A Carneiro1 ◽  
Alex D Oliveira2 ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Surgical Resection ◽  
Primary Lung Cancer ◽  
Cancer Recurrence ◽  
Chest Ct ◽  
Second Primary ◽  
Medical Visits ◽  
Asymptomatic Patients ◽  
Second Primary Lung Cancer

Objective: To report the experience of a routine follow-up program based on medical visits and chest CT. Methods: This was a retrospective study involving patients followed after complete surgical resection of non-small cell lung cancer between April of 2007 and December of 2015. The follow-up program consisted of clinical examination and chest CT. Each follow-up visit was classified as a routine or non-routine consultation, and patients were considered symptomatic or asymptomatic. The outcomes of the follow-up program were no evidence of cancer, recurrence, or second primary lung cancer. Results: The sample comprised 148 patients. The median time of follow-up was 40.1 months, and 74.3% of the patients underwent fewer chest CTs than those recommended in our follow-up program. Recurrence and second primary lung cancer were found in 17.6% and 11.5% of the patients, respectively. Recurrence was diagnosed in a routine medical consultation in 69.2% of the cases, 57.7% of the patients being asymptomatic. Second primary lung cancer was diagnosed in a routine medical appointment in 94.1% of the cases, 88.2% of the patients being asymptomatic. Of the 53 patients who presented with abnormalities on chest CT, 41 (77.3%) were diagnosed with cancer. Conclusion: Most of the cases of recurrence, especially those of second primary lung cancer, were confirmed by chest CT in asymptomatic patients, indicating the importance of a strict follow-up program that includes chest CTs after surgical resection of lung cancer.

scholarly journals A case of second primary lung cancer diagnosed by surgical resection at salvage setting

2018 ◽  
Vol 7 (3) ◽  
pp. 84-86
Author(s):  
Shozo Sakata ◽  
Tetsuya Mizuno ◽  
Hitoshi Dejima ◽  
Takaaki Arimura ◽  
Hiroaki Kuroda ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Surgical Resection ◽  
Primary Lung Cancer ◽  
Second Primary ◽  
Second Primary Lung Cancer

scholarly journals Outcomes after Contralateral Anatomic Surgical Resection in Multiple Lung Cancer

2020 ◽  
Author(s):  
Alex Fourdrain ◽  
Patrick Bagan ◽  
Olivier Georges ◽  
Sophie Lafitte ◽  
Florence De Dominicis ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Surgical Resection ◽  
Primary Lung Cancer ◽  
Extent Of Resection ◽  
Tumor Stage ◽  
Second Primary ◽  
Term Survival ◽  
Long Term Survival ◽  
Lung Cancers

Abstract Background Patients treated surgically for lung cancer may present synchronous or metachronous lung cancers. The aim of this study was to evaluate outcomes after a second contralateral anatomic surgical resection for lung cancer. Methods We performed a retrospective two-center study, based on a prospective indexed database. Included patients were treated surgically by bilateral anatomic surgical resection for a second primary lung cancer. We excluded nonanatomic resections, benign lesions, and ipsilateral second surgical resections. Results Between January 2011 and September 2018, 55 patients underwent contralateral anatomic surgical resections for lung cancer, mostly for metachronous cancers. The first surgical resection was a lobectomy in most cases (45 lobectomies: 81.8%, 9 segmentectomies: 16.4%, and 1 bilobectomy: 1.8%), and a video-assisted thoracic surgery (VATS) procedure was used in 23 cases (41.8%). The mean interval between the operations was 38 months, and lobectomy was less frequent for the second surgical resection (35 lobectomies: 63.6% and 20 segmentectomies: 36.4%), with VATS procedures performed in 41 cases (74.5%). Ninety-day mortality was 10.9% (n = 6), and 3-year survival was 77%. Risk factor analysis identified the number of resected segments during the second intervention or the total number of resected segments, extent of resection (lobectomy vs. segmentectomy), surgical approach (thoracotomy vs. VATS), tumor stage, and nodal involvement as potential prognostic factors for long-term survival. Conclusion A second contralateral anatomic surgical resection for multiple primary lung cancer is possible, with a higher early mortality rate, but acceptable long-term survival, and should be indicated for carefully selected patients.

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