scholarly journals Pengaruh Pemberian Susu Tinggi Protein terhadap Tingkat Nafsu Makan dan Kadar Glukosa Postprandial

2018 ◽  
Vol 14 (4) ◽  
pp. 329
Author(s):  
Harna Harna ◽  
Clara M.Kusharto ◽  
Katrin Roosita ◽  
Andi Muh Asrul Irawan
Keyword(s):  
Randomized Controlled Trial ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Controlled Trial ◽  
Area Under The Curve ◽  
Experimental Trial ◽  
Randomized Controlled

Susu tinggi protein merupakan makanan kompleks yang mengandung beberapa senyawa bioaktif yang potensial memiliki efek terhadap nafsu makan. Namun, mekanisme susu tinggi protein terhadap nafsu makan masih kurang dipahami pada orang dewasa dengan berat badan kurang. Penelitian bertujuan menganalisis pengaruh susu protein tinggi terhadap tingkat nafsu makan dan glukosa postprandial. Penelitian menggunakan experimental trial desain randomized controlled trial. Subjek dibagi menjadi dua kelompok, yaitu 24 subjek pada kelompok perlakuan dan 23 subjek pada kelompok kontrol. Kelompok perlakuan diberi susu tinggi protein dan kelompok kontrol diberi glukosa. Tingkat nafsu makan meliputi tingkat kelaparan, kepuasan, dan keinginan untuk makan dievaluasi menggunakan Visual Analogue Scale (VAS), yang dianalisis dalam incremental Area Under the Curve (iAUC). Hasil penelitian menunjukkan bahwa ada peningkatan yang signifikan nilai iAUC tingkat rasa lapar pada kelompok perlakuan dibandingkan dengan kontrol (p<0,05), dengan 8881±638,4 min.mm kelompok perlakuan dan 7297,8±439,6 min.mm kelompok kontrol. Tidak ada perbedaan yang signifikan pada tingkat kepuasan dan keinginan untuk makan antara kedua kelompok (p>0,05). Kadar glukosa postprandial pada kelompok perlakuan signifikan (p<0,05) lebih rendah dibandingkan dengan kelompok kontrol. Penelitian ini menyimpulkan bahwa intervensi susu tinggi protein kemungkinan dapat meningkatkan tingkat rasa lapar pada orang dewasa dengan berat badan kurang

Palatoplasty for Snoring: A Randomized Controlled Trial of Three Surgical Methods

1998 ◽  
Vol 119 (3) ◽  
pp. 288-292 ◽  
Author(s):  
R. W. Clarke ◽  
M. P. J. Yardley ◽  
C. M. Davies ◽  
A. Panarese ◽  
R. T. Clegg ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Postoperative Morbidity ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Surgical Methods ◽  
Before And After ◽  
A New Technique ◽  
Surgical Treatments

In a randomized, controlled trial, 62 patients (47 men and 15 women) with severe antisocial snoring, but no sleep apnea, were allocated to one of three surgical treatments. These were uvulopalato-pharyngoplasty, laser palatoplasty, and diathermy palatoplasty. Postoperative morbidity was measured on a visual analogue scale of severity of pain, dysphagia, and nasal regurgitation at 1, 2, and 7 days after the operation. Efficacy of each procedure was measured by asking the sleeping partner to record the severity of snoring before and after the operation, again on a visual analogue scale. Measurements were taken at 1, 3, and 6 months. There were no significant differences in early postoperative morbidity among the treatment groups. Diathermy palatoplasty is a new technique for the relief of snoring that is associated with low morbidity and requires little in the way of expensive equipment.

scholarly journals COMPARISON OF PAIN SCORE IN OSTEOARTHRITIS PATIENTS TREATED WITH A COMBINATION OF DIACEREIN AND MELOXICAM AND MELOXICAM ALONE

2017 ◽  
Vol 9 (6) ◽  
pp. 69
Author(s):  
Ni Made Oka Dwicandra ◽  
Antonious Adji Prayitno Setiadi
Keyword(s):  
Randomized Controlled Trial ◽  
Articular Cartilage ◽  
Combination Therapy ◽  
Pain Intensity ◽  
Pain Score ◽  
Controlled Trial ◽  
Area Under The Curve ◽  
Randomized Controlled ◽  
Pain Outcome ◽  
Inflammatory Drugs

Objective: Osteoarthritis (OA) is a progressive chronic disease with the loss of articular cartilage. In managing OA, inadequate pain relief (IPR) often occurs, particularly with a single non steroidal anti-inflammatory drugs (NSAIDs) therapy. In this research, pain outcome of OA patients treated with a combination of diacerein and meloxicam vs meloxicam alone was evaluated.Methods: This research was conducted at rumah sakit umum daerah (RSUD) Dr. Mohammad Soewandhie Surabaya by using randomized controlled trial (RCT) design. Pain outcome was evaluated by pain intensity and area under the curve (AUC) of pain score in week 0-4th.Results: There were a significantly different (p<0.05) in pain intensity seen in 3rd and 4th weeks after treated with a combination of diacerein and meloxicam, and with meloxicam only. However, there were no different in AUC pain score between combination and single therapy.Conclusion: Combination therapy of diacerein and meloxicam was more effective than meloxicam alone. A significant effect of a combination therapy of diacerein and meloxicam occurred at 3rd weeks. The prolong study in order to get the differences in AUC pain score are needed.

scholarly journals The Effect of Initial Oxygen Exposure on Diaphragm Activity in Preterm Infants at Birth

2021 ◽  
Vol 9 ◽  
Author(s):  
Ruud W. van Leuteren ◽  
Anouk W. J. Scholten ◽  
Janneke Dekker ◽  
Tessa Martherus ◽  
Frans H. de Jongh ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Preterm Infants ◽  
Controlled Trial ◽  
Statistical Significance ◽  
Area Under The Curve ◽  
Low Oxygen ◽  
Randomized Controlled ◽  
Oxygen Group ◽  
Breathing Effort ◽  
Diaphragm Activity

Background: The initial FiO2 that should be used for the stabilization of preterm infants in the delivery room (DR) is still a matter of debate as both hypoxia and hyperoxia should be prevented. A recent randomized controlled trial showed that preterm infants [gestational age (GA) &lt; 30 weeks] stabilized with an initial high FiO2 (1.0) had a significantly higher breathing effort than infants stabilized with a low FiO2 (0.3). As the diaphragm is the main respiratory muscle in these infants, we aimed to describe the effects of the initial FiO2 on diaphragm activity.Methods: In a subgroup of infants from the original bi-center randomized controlled trial diaphragm activity was measured with transcutaneous electromyography of the diaphragm (dEMG), using three skin electrodes that were placed directly after birth. Diaphragm activity was compared in the first 5 min after birth. From the dEMG respiratory waveform several outcome measures were determined for comparison of the groups: average peak- and tonic inspiratory activity (dEMGpeak and dEMGton, respectively), inspiratory amplitude (dEMGamp), area under the curve (dEMGAUC) and the respiratory rate (RR).Results: Thirty-one infants were included in this subgroup, of which 29 could be analyzed [n = 15 (median GA 28.4 weeks) and n = 14 (median GA 27.9 weeks) for the 100 and 30% oxygen group, respectively]. Tonic diaphragm activity was significantly higher in the high FiO2-group (4.3 ± 2.1 μV vs. 2.9 ± 1.1 μV; p = 0.047). The other dEMG-parameters (dEMGpeak, dEMGamp, dEMGAUC) showed consistently higher values in the high FiO2 group, but did not reach statistical significance. Average RR showed similar values in both groups (34 ± 9 vs. 32 ± 10 breaths/min for the high and low oxygen group, respectively).Conclusion: Preterm infants stabilized with an initial high FiO2 showed significantly more tonic diaphragm activity and an overall trend toward a higher level of diaphragm activity than those stabilized with an initial low FiO2. These results confirm that a high initial FiO2 after birth stimulates breathing effort, which can be objectified with dEMG.

The effectiveness of 12 weeks of Pilates intervention on disability, pain and kinesiophobia in patients with chronic low back pain: a randomized controlled trial

2018 ◽  
Vol 32 (9) ◽  
pp. 1249-1257 ◽  
Author(s):  
David Cruz-Díaz ◽  
Marta Romeu ◽  
Carmen Velasco-González ◽  
Antonio Martínez-Amat ◽  
Fidel Hita-Contreras
Keyword(s):  
Randomized Controlled Trial ◽  
Low Back Pain ◽  
Back Pain ◽  
Analogue Scale ◽  
Controlled Trial ◽  
Intervention Group ◽  
Control Group ◽  
Low Back ◽  
Randomized Controlled ◽  
Disability Questionnaire

Objective: To assess the effectiveness of 12 weeks of Pilates practice on disability, pain and kinesiophobia in patients with chronic non-specific low back pain. Design: This is a randomized controlled trial. Setting: This study was conducted in the university laboratory. Subjects: A total of 64 participants with chronic non-specific low back pain were included. Interventions: Participants were randomly allocated to intervention group consisted in Pilates intervention during 12 weeks ( n = 32) or control group who received no treatment ( n = 32). Main measures: Disability, pain and kinesiophobia were assessed by Roland Morris Disability Questionnaire, visual analogue scale and Tampa Scale of Kinesiophobia, respectively. Measurements were performed at baseline, at 6 and 12 weeks after study completion. Results: There were significant differences between groups with observed improvement in Pilates intervention group in all variables after treatment ( P < 0.001). Major changes on disability and kinesiophobia were observed at six weeks of intervention with no significant difference after 12 weeks ( P < 0.001). Mean changes of the intervention group compared with the control group were 4.00 (0.45) on the Roland Morris Disability Questionnaire and 5.50 (0.67) in the Tampa Scale of Kinesiophobia. Pain showed better results at six weeks with a slightly but statistically significant improvement at 12 weeks with Visual Analogue Scale scores of 2.40 (0.26) ( P < 0.001). Conclusion: Pilates intervention in patients with chronic non-specific low back pain is effective in the management of disability, pain and kinesiophobia.

scholarly journals The Efficacy And Safety of Traditional Chinese Medicine (TCM) To The Patient With Dizziness In Emergency Department — A Randomized Controlled Trial

2021 ◽  
Author(s):  
Chih-Wen Chiu ◽  
Tsung-Chieh Lee ◽  
Chia-Yun Chen ◽  
Lun-Chien Lo
Keyword(s):  
Heat Treatment ◽  
Emergency Department ◽  
Randomized Controlled Trial ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Analogue Scale ◽  
Controlled Trial ◽  
Far Infrared ◽  
Efficacy And Safety ◽  
Randomized Controlled

Abstract • Background: A new way of heat treatment with far-infrared and / or acupuncture on acupoints is studied to treat the stubborn dizziness of patients.• Methods: A single-blinded 4-arms parallel randomized controlled trial is designed: arm of acupuncture, arm of far-infrared, arm of acupuncture plus far-infrared, arm of placebo with no far-infrared. There are four acupoints on left limbs and four acupoints on right limbs correspondingly, named as Neiguan (PC6), Hegu (LI4), Zusanli (ST36), and Taichong (LR3). The intervention time is 20 minutes for each. After treatment, visual analogue scale of dizziness, dizziness handicap intervention questionnaire and heart rate variability are used to measure and evaluate the results.• Discussion: This is a prior study in use of far-infrared and / or acupuncture on acupoints for the treatment of stubborn dizziness. It promotes the basis to further acupoints treatment according to the concept of traditional Chinese medicine.• Trial registration: It was registered in ClinicalTrials.gov with number NCT04415307 on date June 1, 2020.

scholarly journals Can sedation using a combination of propofol and dexmedetomidine enhance the satisfaction of the endoscopist in endoscopic submucosal dissection?

2018 ◽  
Vol 06 (01) ◽  
pp. E3-E10 ◽  
Author(s):  
Takashi Nonaka ◽  
Masahiko Inamori ◽  
Tetsuya Miyashita ◽  
Yumi Inoh ◽  
Kenji Kanoshima ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Endoscopic Submucosal Dissection ◽  
Analogue Scale ◽  
Controlled Trial ◽  
Combination Group ◽  
Randomized Controlled ◽  
Sedation Protocol ◽  
Submucosal Dissection ◽  
Group 2 ◽  
Pilot Randomized Controlled Trial

Abstract Background and study aims The aim of this pilot randomized controlled trial was to evaluate and compare the satisfaction of the endoscopist along with the effectiveness and safety of sedation between sedation protocol using a combination of propofol (PF) and dexmedetomidine (DEX) (Combination group) and sedation protocol using PF alone (PF group) during gastric endoscopic submucosal dissection (ESD). Patients and methods Fifty-eight patients with gastric neoplasias scheduled for gastric ESD were enrolled and randomly assigned to the two groups. The satisfaction scores of the endoscopists and the parameters for the effectiveness and safety of sedation were evaluated by comparisons between the two groups. Results The satisfaction scores of the endoscopists, which were measured using a visual analogue scale, were significantly higher in the Combination group than in the PF group (88 vs. 69, P = 0.003). The maintenance dose of PF was lower in the Combination group than in the PF group (2 mg/kg/h vs. 5 mg/kg/h, P < 0.001), and the number of rescue PF injections was fewer in the Combination group than in the PF group (2 times vs. 6 times, P < 0.001). The incidence of bradycardia (defined as a pulse rate ≤ 45 bpm) in the Combination group was higher than that in the PF group (37.9 % vs. 10.3 %, P = 0.029). Conclusions This study suggests that gastroenterologist-directed sedation using a combination of PF and DEX during gastric ESD can enhance the satisfaction levels of endoscopists by providing stable sedation with an acceptable safety profile.

Efficacy of an innovative smartphone application for office workers with chronic non-specific low back pain: a pilot randomized controlled trial

2020 ◽  
Vol 34 (10) ◽  
pp. 1282-1291
Author(s):  
Khader A Almhdawi ◽  
Donia Saleh Obeidat ◽  
Saddam F Kanaan ◽  
Alaa O Oteir ◽  
Zaid Modhi Mansour ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Randomized Controlled Trial ◽  
Analogue Scale ◽  
Controlled Trial ◽  
Smartphone Application ◽  
Office Workers ◽  
Evidence Based ◽  
Low Back ◽  
Randomized Controlled

Objective: To evaluate the efficacy of a newly developed evidence-based low back pain (LBP) management smartphone application. Design: A double-blinded randomized controlled trial where participants randomly assigned to either an experimental group (EG) or a control group (CG). Setting: Governmental and private institutions. Participants: About 40 office workers, aged 30 to 55 years, had pain due to non-specific LBP > 3 on Visual Analogue Scale, and with pain chronicity > 3 months. Interventions: The EG received full version of the application ‘Relieve my back’ included evidence-based instructions and therapeutic exercises for LBP management, whereas the CG received placebo version included instructions about nutrition. Main measures: Primary outcome measures included pain measured by Visual Analogue Scale (VAS), disability measured by Oswestry Disability Index (ODI), and quality of life measured by Short-Form Health Survey (SF-12). Results: Following six weeks of using the application, compared to CG, the EG group demonstrated significant decrease in pain intensity (−3.45 (2.21) vs −0.11 (1.66), P < 0.001), in ODI score (−11.05 (10.40) vs −0.58 (9.0), P = 0.002), and significant increase in physical component of SF-12 (12.85 (17.20) vs −4.63 (12.04), P = 0.001). Conclusion: ‘Relieve my back’ application might be efficacious in reducing pain and disability and improving the quality of life of office workers with non-specific LBP.

scholarly journals A Clinical Study Comparing the Efficacy of SesameOil with Desensitizing Tooth Paste in Reducing Dentinal Hypersensitivity: A Randomized Controlled Trial

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Walaa Abdullah Al Qahtani ◽  
N. C. Sandeepa ◽  
Eman Khalid Abdullah ◽  
Yosra Mohammed Mousa ◽  
Atheer Abdulhade Ganem ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Analogue Scale ◽  
Controlled Trial ◽  
Sesame Oil ◽  
Dentin Hypersensitivity ◽  
Therapeutic Effectiveness ◽  
Randomized Controlled ◽  
Time Periods ◽  
Dentinal Hypersensitivity

Context. Several treatments are available for management of dentinal hypersensitivity, most routinely recommended one being desensitizing tooth paste with variable results. This is a clinical trial to study the therapeutic effectiveness of sesame oil which is an essential oil, a commonly available household traditional medicine with several health benefits. Objectives. The objective of this study was to evaluate the efficacy of sesame oil therapy in reduction of dentin hypersensitivity, as compared to desensitizing dentifrice. Design, setting, participants. We conducted a single blinded randomized controlled trial in 100 patients reported to Diagnostic Department of King Khalid University-College of Dentistry between March 2018 and December 2019. Interventions. Patients were given desensitizing tooth paste or sesame oil to apply for the specified time. Main outcome measures. A Visual Analogue Scale was used to record sensitivity scores for controlled air stimulus and tactile method at the first visit and after 8th week of treatment. Measured outcome was reduction in dentinal hypersensitivity. Results. Hypersensitivity degree before treatment in case of desensitizing tooth paste was 6.90 ± 1.04, and posttreatment showed a score of 4.70 ± 1.37. In case of sesame oil groups, subjects included had a score of 7.14 ± 0.90 which showed a drop to a score of 4.52 ± 1.16. Conclusions. Desensitizing tooth paste showed 30.5% reduction in sensitivity, whereas sesame oil application showed 36.2% reduction. The belief of considering oil therapy in oral health is just a placebo effect and may not be considered anymore. Efficacy can be established with many more studies including long follow-up and varying time periods.

Sign in / Sign up

Export Citation Format

Share Document