Evaluation of the life quality in patients with diabetic foot syndrome before treatment and in the late period

2019 ◽  
Vol 0 (2) ◽  
pp. 56-60
Author(s):  
O. V. Marchenko ◽  
M. B. Gorobeiko ◽  
T. Yu. Yuzvenko ◽  
Z. G. Krushinska
Keyword(s):  
Diabetic Foot ◽  
Life Quality ◽  
Diabetic Foot Syndrome ◽  
Late Period

The effect of rheopheresis treatment on the cytokine profile in diabetic foot syndrome with hyperviscosity in the aspect of clinical changes: A preliminary study

2021 ◽  
pp. 1-9
Author(s):  
Kristof Gal ◽  
Katalin Veres ◽  
Sándor Halmi ◽  
Krisztina Bozoki-Beke ◽  
Klara Fekete ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Whole Blood ◽  
Life Quality ◽  
Foot Ulcer ◽  
Serum Levels ◽  
Plasma Viscosity ◽  
Cytokine Profile ◽  
Diabetic Foot Syndrome ◽  
Tnf Alpha ◽  
Preliminary Study

BACKGROUND: Rheopheresis is a selective extracorporal double cascade filtration treatment, which can extract high molecular weight proteins being responsible for hyperviscosity. As the whole blood and plasma viscosity decrease microcirculation improves. OBJECTIVE: In this preliminary study we aimed to analyze additional beneficial effects of rheopheresis treatment with changes of pro-inflammantory cytokine levels in diabetic foot syndrome patients. METHODS: Two rheopheresis treatments were performed for 6 patients with diabetic foot ulcer and/or neuropathy on consecutive days. Before and after the treatments whole blood and plasma viscosity, as well as IL-6, IL-8, and TNF-alpha serum levels were determined, and complex angiological and ENG examinations were performed. RESULTS: Rheopheresis decreased the whole blood and plasma viscosity, and the serum levels of IL-6, IL-8, and TNF-alpha were markedly reduced. The life quality of the patients improved, the ulcers healed, the pain decreased. Daily dose of analgesics decreased in the follow-up period (6 months). The ENG showed improving amplitude and/or normalizing conduction speed. CONCLUSION: Application of rheopheresis in patients with diabetic foot syndrome has a beneficial effect, providing favorable rheological condition, normalizing cytokine profile and reducing the sensorineural symptoms.

Screening of Kazakhstan plants useful in the treatment of diabetic foot syndrome

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
TS Kustova ◽  
LK Mamonov ◽  
CL Cantrell ◽  
SA Ross
Keyword(s):  
Diabetic Foot ◽  
Diabetic Foot Syndrome

Improvement of specialised help to patient with diabetic foot syndrome in Uzbekistan

2017 ◽  
Author(s):  
Nilufar Ibragimova ◽  
Telman Kamalov ◽  
Hamidulla Shakirov ◽  
Oxana Platonova ◽  
Lyudmila Kokareva
Keyword(s):  
Diabetic Foot ◽  
Diabetic Foot Syndrome

scholarly journals The diabetic foot syndrome - therapy

2004 ◽  
Vol 129 (14) ◽  
pp. 751-754 ◽  
Author(s):  
H P Lorenzen ◽  
H Schunkert
Keyword(s):  
Diabetic Foot ◽  
Diabetic Foot Syndrome

Pro- and Anti-Angiogenic Factors: Their Relevance in Diabetic Foot Syndrome—A Review

Angiology ◽  
2021 ◽  
pp. 000331972110426
Author(s):  
Martyna Schönborn ◽  
Patrycja Łączak ◽  
Paweł Pasieka ◽  
Sebastian Borys ◽  
Anna Płotek ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Healing Process ◽  
Arterial Disease ◽  
Angiogenic Factors ◽  
Diabetic Foot Syndrome ◽  
Tissue Loss ◽  
Comprehensive Treatment ◽  
Diabetic Patients ◽  
Impaired Wound Healing ◽  
Peripheral Arterial

Peripheral arterial disease can involve tissue loss in up to 50% of patients with diabetic foot syndrome (DFS). Consequently, revascularization of narrowed or occluded arteries is one of the most common forms of comprehensive treatment. However, technically successful angioplasty does not always result in the healing of ulcers. The pathomechanism of this phenomenon is still not fully understood, but inadequate angiogenesis in tissue repair may play an essential role. Changes in pro- and anti-angiogenic factors among patients with DFS are not always clear and conclusive. In particular, some studies underline the role of decreased concentration of pro-angiogenic factors and higher levels of anti-angiogenic mediators. Nevertheless, there are still controversial issues, including the paradox of impaired wound healing despite high concentrations of some pro-angiogenic factors, dynamics of their expression during the healing process, and their mutual relationships. Exploring this process among diabetic patients may provide new insight into well-known methods of treatment and show their real benefits and chances for improving outcomes.

scholarly journals Treatment of the diabetic foot infections in septic surgery unit of the municipal versatile hospital

2015 ◽  
Vol 14 (1) ◽  
pp. 60-66
Author(s):  
A. A. Protasov ◽  
N. A. Bubnova ◽  
M. A. Shatil ◽  
A. S. Soloveichik ◽  
K. S. Suprun ◽  
...  
Keyword(s):  
Diabetic Foot ◽  
Volume Flow ◽  
Diabetic Foot Syndrome ◽  
Complex Treatment ◽  
Peripheral Speed ◽  
Diabetic Foot Infections ◽  
Complex Therapy ◽  
Popliteal Block ◽  
Surgical Unit

Experience of surgical and complex treatment more than 2500 patients with the purulent and necrotic complications of various forms of a diabetic foot syndrome was generalized. The number of such patients in our unit for the last fifth anniversary in comparison with previous years was doubled. At an ischemic form vasodilating complex therapy was carried out. At the femoral and popliteal block with a limited distal necrosis autovenous shunting with the subsequent economical necretomy was carried out, without sending of the patient from the septic surgical unit. In a case of the neuropathic form of a diabetic foot syndrome drainage of suppurative focuses, economical and sometimes repeated necretomies at various levels of the foot was made. It allowed us to keep foot of the patient for an extremity support in 80 % of the all cases. Frequency of high amputations in recent years was reduced, at the level of a femur from 13 to 1.4 %, at the level of a shin - from 11.5 to 5.8 %. In diagnostics, operation scoping and an assessment of effectiveness of treatment, researches of microcirculation by means of the device «Minimax-Doppler-К» were used. When the indexes of the peripheral speed of a linear bloodflow more than 1.6 mm/sec and rate of volume flow more than 0.0128 ml/min reamputation was not required.

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