The paper reviews the major ways of reducing failure cases during drilling works on the territory of Azerbaijan and South Caspian basin, as well as in oil-gas bearing structures of the Caspian Sea considering geodynamic tension of reservoirs, seismic activity and the occurrences of velocity changes. If not considering such aspects as seismodynamic activity of the territory and geodynamic tensions, failure and complication risks in the process of deep well drilling sharply increase. Physical-chemical features of rocks in the same formation are not similar and various patterns of complicated seismic record can be seen. It is necessary to study in detail the patterns of seismic record in different directions of seismic profile passing near the location selected for the project well. Foremost, it is significant to reveal the interval of drilled reservoir, where the complicated record is occurred and specify the reasons for the sharp difference in wave field patterns. Moreover, while conducting drilling works in the areas with complicated features, the failure case risks should be considered as well.