VOLATILE COMPOUND ANALYSIS USING GC-MS, PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL ACTIVITIES OF BRASSICA OLERACEA VAR. CAPITATA F. RUBRA

The search for antimalarial compounds has been necessitated by the resistance of Plasmodium falciparum to almost all antimalarial drugs. The aim of this research was to determine in-vitro antimalarial activity of extracts of some indigenous plants species in Kebbi State. Plant extraction was carried-out by maceration using ethanol and water as solvent. The antiplasmodial activity of the extracts was evaluated against fresh clinical isolates of P. falciparum using WHO method of in-vitro micro test. Phytochemical screening was also carried out on the extract to deduce the active chemicals present in the plant extract. All plant extracts demonstrate dose dependent antimicrobial activities with IC50 Less than 50%. However highest growth inhibition of the P. falciparum was demonstrated by aqueous and ethanol extract of A. indica with IC50 7.4µg/ml and 8.6µg/ml respectively followed by ethanol and aqueous extract of C. occidentalis with IC50 15.3µg/ml and 18.0µg/ml respectively. Least antimalarial activity was demonstrated by aqueous extract of M. oleifera with IC50 33.5µg/ml while ethanolic extract of M. oleifera demonstrated IC50 of 20.50µg/ml. M. indica ethanolic and aqueous extract also demonstrated moderate antimalarial activity with IC50 18.8µg/ml and 24.5µg/ml. The phytochemical screening of medicinal plants showed the presence of tannins, saponins, alkaloids, flavonoid, phenol and cardiac glycosides in the extracts, which may be responsible for the antiplasmodial activity. This result justifies the traditional use of the plant in malaria treatment and further research is suggested to identify and characterize the active principles from the plants. Keywords: Antimalaria, Invitro, Medicinal Plants, Malaria, Kebbi

Download Full-text

Gel Formulation of Ethyl Acetate Garlic Extraction and Its Activity Against Staphylococcus Epidermis

Journal of Chemical Natural Resources ◽

10.32734/jcnar.v1i2.1255 ◽

2019 ◽

Vol 1 (2) ◽

pp. 69-78

Author(s):

Khairan Khairan

Keyword(s):

Ethyl Acetate ◽

Staphylococcus Epidermidis ◽

Antimicrobial Activities ◽

Phytochemical Screening ◽

Viscosity Property ◽

Antibacterial And Antifungal Activities ◽

Staphylococcus Epidermis ◽

Homogeneity Property ◽

The Stability ◽

Antibacterial And Antifungal

Garlic is known to have antibacterial and antifungal activities. This research aims to formulate the gel materials extracted from the garlic and to investigate the antimicrobial activities to Staphylococcus epidermidis. The phytochemical screening showed that the gel materials of ethyl acetate consisted alkaloid, flavonoid, and saponin substances. The formulation of gel was synthesized with different variations of 1, 5, and 10%. In this research, the gel materials were analyzed to understand the stability, homogeneity, pH, viscosity and dispersive powers. The results showed that good abilities of gel based on the taste, aroma and consistency, while the homogeneity property of each samples is influenced by the presence of gel concentration. The viscosity property of gels accounted for 3201.02-1664.04 Cps with 2.95-3.8 cm of dispersive powers. The ability of antimicrobial showed that higher concentration of 5% and 10% gels showed greater inhibitory zones of 18,10 and 22,08 mm compared to 1% of concentration

Download Full-text

Phytochemical screening, antioxidant, and antimicrobial activities of the crude leaves′ extract from Ipomoea batatas (L.) Lam

Pharmacognosy Magazine ◽

10.4103/0973-1296.80682 ◽

2011 ◽

Vol 7 (26) ◽

pp. 165 ◽

Cited By ~ 30

Author(s):

FranciscoCarlos Groppo ◽

MárciaThaís Pochapski ◽

ElianaCristina Fosquiera ◽

LuísAntônio Esmerino ◽

ElizabeteBrasil dos Santos ◽

...

Keyword(s):

Ipomoea Batatas ◽

Antimicrobial Activities ◽

Phytochemical Screening ◽

Antioxidant And Antimicrobial Activities

Download Full-text

Phytochemical screening and evaluation of in vitro antioxidant and antimicrobial activities of the indigenous medicinal plant Albizia odoratissima

Pharmaceutical Biology ◽

10.1080/13880209.2017.1291694 ◽

2017 ◽

Vol 55 (1) ◽

pp. 1155-1161 ◽

Cited By ~ 21

Author(s):

Venkanna Banothu ◽

Chandrasekharnath Neelagiri ◽

Uma Adepally ◽

Jayalakshmi Lingam ◽

Kesavaharshini Bommareddy

Keyword(s):

Medicinal Plant ◽

Antimicrobial Activities ◽

Phytochemical Screening ◽

Antioxidant And Antimicrobial Activities

Download Full-text

A COMPARATIVE ASSESSMENT OF PHYTOCHEMICAL SCREENING, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES BETWEEN LEAF AND DUST OF BLACK TEA EXTRACTS

International Journal of Research in Ayurveda and Pharmacy ◽

10.7897/2277-4343.076247 ◽

2017 ◽

Vol 7 (6) ◽

pp. 90-95

Author(s):

Shreya Mandal ◽

Animesh Samanta ◽

Arpita Patra ◽

Shrabani Pradhan ◽

Suchismita Roy ◽

...

Keyword(s):

Black Tea ◽

Antimicrobial Activities ◽

Comparative Assessment ◽

Phytochemical Screening ◽

Antioxidant And Antimicrobial Activities

Download Full-text

Phytochemical screening and in vitro antimicrobial activities of Mimosa invisa Mart. leaves and stems

Bioscience Horizons The International Journal of Student Research ◽

10.1093/biohorizons/hzy019 ◽

2018 ◽

Vol 11 ◽

Author(s):

Henry C Chukwudi ◽

Chinelo A Ezeabara

Keyword(s):

Antimicrobial Activities ◽

Phytochemical Screening

Download Full-text

Phytochemical Screening, Antimicrobial Activities and Nutritional content of Jatropha Tanjorensis Leaves

NIGERIAN ANNALS OF PURE AND APPLIED SCIENCES ◽

10.46912/napas.114 ◽

2019 ◽

Vol 1 ◽

pp. 108-113

Author(s):

B A Anhwange ◽

I G Agbidye ◽

B A Kyenge ◽

P O Ngbede

Keyword(s):

Proximate Composition ◽

Antimicrobial Agents ◽

Reducing Sugars ◽

Antimicrobial Properties ◽

Antimicrobial Activities ◽

Phytochemical Screening ◽

Bioactive Components ◽

Standard Procedures ◽

Hexane Extracts

The leaves of Jatropha tanjarensis were collected and assessed for their phytochemical compositions and antimicrobial activities using methanolic and hexane extracts as to determine the bioactive components and their effects on microorganisms. Also, the nutritional potential was investigated through the determination of proximate composition using standard procedures. The result of phytochemical screening indicated the presence of saponins, cardiac glycosides, reducing sugars, steroids, alkaloids and flavonoids in methanolic extract, the same observation was recorded in n-hexane extract except that reducing sugars were absent and phlobotannins were present. The antimicrobial activities of the leaves extract show that it have some antimicrobial properties. Results of the proximate composition and mineral analysis revealed that the plant is a good source of fiber and minerals. Therefore, leaves of Jatropha tanjarensisapart from being used as antimicrobial agents, can serve as good sources of fiber and minerals when used as vegetables.

Download Full-text