Auditory-Evoked Potential Correlates of Susceptibility to Noise-Induced Hearing Loss

1985 ◽  
Vol 24 (2) ◽  
pp. 149-156 ◽  
Author(s):  
J. Attias ◽  
H. Pratt
Keyword(s):  
Hearing Loss ◽  
Evoked Potential ◽  
Auditory Evoked Potential ◽  
Noise Induced Hearing Loss ◽  
Susceptibility To Noise

scholarly journals Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss

PLoS Genetics ◽  
2015 ◽  
Vol 11 (4) ◽  
pp. e1005094 ◽  
Author(s):  
Joel Lavinsky ◽  
Amanda L. Crow ◽  
Calvin Pan ◽  
Juemei Wang ◽  
Ksenia A. Aaron ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Genome Wide Association ◽  
Noise Induced Hearing Loss ◽  
Genome Wide ◽  
Susceptibility To Noise

Individual Susceptibility to Noise-Induced Hearing loss

1993 ◽  
Vol 14 (3) ◽  
pp. 152-168 ◽  
Author(s):  
Donald Henderson ◽  
Malini Subramaniam ◽  
Flint A. Boettcher
Keyword(s):  
Hearing Loss ◽  
Noise Induced Hearing Loss ◽  
Individual Susceptibility ◽  
Susceptibility To Noise

Susceptibility to Noise-Induced Hearing Loss: Review and Future Directions

1984 ◽  
Vol 149 (3) ◽  
pp. 154-158 ◽  
Author(s):  
Ernest L. Hepler ◽  
Michael J. Moul ◽  
Kenneth J. Gerhardt
Keyword(s):  
Hearing Loss ◽  
Noise Induced Hearing Loss ◽  
Future Directions ◽  
Susceptibility To Noise

Deficiency in plasma membrane calcium ATPase isoform 2 increases susceptibility to noise-induced hearing loss in mice

2002 ◽  
Vol 164 (1-2) ◽  
pp. 231-239 ◽  
Author(s):  
Peter J Kozel ◽  
Rickie R Davis ◽  
Edward F Krieg ◽  
Gary E Shull ◽  
Lawrence C Erway
Keyword(s):  
Hearing Loss ◽  
Plasma Membrane ◽  
Calcium Atpase ◽  
Noise Induced Hearing Loss ◽  
Plasma Membrane Calcium Atpase ◽  
Susceptibility To Noise

Low-level otoacoustic emissions may predict susceptibility to noise-induced hearing loss

2006 ◽  
Vol 120 (1) ◽  
pp. 280-296 ◽  
Author(s):  
Judi A. Lapsley Miller ◽  
Lynne Marshall ◽  
Laurie M. Heller ◽  
Linda M. Hughes
Keyword(s):  
Hearing Loss ◽  
Otoacoustic Emissions ◽  
Noise Induced Hearing Loss ◽  
Low Level ◽  
Susceptibility To Noise

scholarly journals Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice

2016 ◽  
Vol 2016 ◽  
pp. 1-16 ◽  
Author(s):  
Xiaolong Fu ◽  
Linqing Zhang ◽  
Yecheng Jin ◽  
Xiaoyang Sun ◽  
Aizhen Zhang ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Outer Hair Cell ◽  
Cell Loss ◽  
Acoustic Trauma ◽  
Noise Induced Hearing Loss ◽  
Wild Type ◽  
Auditory Function ◽  
Susceptibility To Noise ◽  
Susceptible Gene

MYH14 is a member of the myosin family, which has been implicated in many motile processes such as ion-channel gating, organelle translocation, and the cytoskeleton rearrangement. Mutations in MYH14 lead to a DFNA4-type hearing impairment. Further evidence also shows that MYH14 is a candidate noise-induced hearing loss (NIHL) susceptible gene. However, the specific roles of MYH14 in auditory function and NIHL are not fully understood. In the present study, we used CRISPR/Cas9 technology to establish a Myh14 knockout mice line in CBA/CaJ background (now referred to as Myh14−/−mice) and clarify the role of MYH14 in the cochlea and NIHL. We found that Myh14−/−mice did not exhibit significant hearing loss until five months of age. In addition, Myh14−/−mice were more vulnerable to high intensity noise compared to control mice. More significant outer hair cell loss was observed in Myh14−/−mice than in wild type controls after acoustic trauma. Our findings suggest that Myh14 may play a beneficial role in the protection of the cochlea after acoustic overstimulation in CBA/CaJ mice.

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