scholarly journals Dosimetric Intercomparison at the Scandinavian Radiation Therapy Centres I. Absorbed Dose Intercomparison

1982 ◽  
Vol 21 (1) ◽  
pp. 1-10 ◽  
Author(s):  
K.-A. Johansson ◽  
L. O. Mattsson ◽  
H. Svensson
Author(s):  
Hugo Levillain ◽  
Oreste Bagni ◽  
Christophe M. Deroose ◽  
Arnaud Dieudonné ◽  
Silvano Gnesin ◽  
...  

Abstract Purpose A multidisciplinary expert panel convened to formulate state-of-the-art recommendations for optimisation of selective internal radiation therapy (SIRT) with yttrium-90 (90Y)-resin microspheres. Methods A steering committee of 23 international experts representing all participating specialties formulated recommendations for SIRT with 90Y-resin microspheres activity prescription and post-treatment dosimetry, based on literature searches and the responses to a 61-question survey that was completed by 43 leading experts (including the steering committee members). The survey was validated by the steering committee and completed anonymously. In a face-to-face meeting, the results of the survey were presented and discussed. Recommendations were derived and level of agreement defined (strong agreement ≥ 80%, moderate agreement 50%–79%, no agreement ≤ 49%). Results Forty-seven recommendations were established, including guidance such as a multidisciplinary team should define treatment strategy and therapeutic intent (strong agreement); 3D imaging with CT and an angiography with cone-beam-CT, if available, and 99mTc-MAA SPECT/CT are recommended for extrahepatic/intrahepatic deposition assessment, treatment field definition and calculation of the 90Y-resin microspheres activity needed (moderate/strong agreement). A personalised approach, using dosimetry (partition model and/or voxel-based) is recommended for activity prescription, when either whole liver or selective, non-ablative or ablative SIRT is planned (strong agreement). A mean absorbed dose to non-tumoural liver of 40 Gy or less is considered safe (strong agreement). A minimum mean target-absorbed dose to tumour of 100–120 Gy is recommended for hepatocellular carcinoma, liver metastatic colorectal cancer and cholangiocarcinoma (moderate/strong agreement). Post-SIRT imaging for treatment verification with 90Y-PET/CT is recommended (strong agreement). Post-SIRT dosimetry is also recommended (strong agreement). Conclusion Practitioners are encouraged to work towards adoption of these recommendations.


2021 ◽  
pp. 56-59
Author(s):  
Irina M. Lebedenko ◽  
Sergej S. Khromov ◽  
Taras V. Bondarenko ◽  
Evgenij M. Chertenkov

Considered the issues of X-ray dose control during diagnostic and therapeutic procedures using imaging tools. The dose of X-ray radiation from the visualization devices absorbed by the biological tissue of a person was determined when monitoring the position of the patient on the therapeutic table of the electron accelerator before the radiation therapy session. The processes of transmission of photons and electrons through the medium were simulated, and the X-ray spectra were measured. The emission spectrum of the Varian G-242 Rotating Anode X-ray Tube was obtained using an XR-100-CdTe spectrometer. The absorbed dose is calculated by the Monte Carlo method. The absorbed dose in the water phantom at tube voltage up to 80 kV was 0,9–1,5 mGy.


1998 ◽  
Vol 43 (2) ◽  
pp. 261-276 ◽  
Author(s):  
Sven Å Johansson Bäck ◽  
Peter Magnusson ◽  
Annette Fransson ◽  
Lars E Olsson ◽  
Anders Montelius ◽  
...  

2018 ◽  
Vol 7 (2) ◽  
pp. 19-24
Author(s):  
V. A. Titova ◽  
D. A. Kokontsev ◽  
T. S. Belle

The use of multicomponent methods of special treatment (surgery, polychemotherapy, radiation therapy, laser photodynamic therapy) in oncology requires the control of doses in the tumor and healthy organs with high accuracy. A method of direct dosimetry using fiber-optic scintillation dosimeter MCD-4 is proposed. The dosimeter is fixed on endostats and is visualized on CT/MRI. The coordinates are entered into the anatomical units and dosimetry calculations, the data are mapped, the doses are adjusted on medical grounds. The developed technique of direct dosimetry allows monitoring of the contact radiation therapy (CRT) procedure in real time and making the necessary changes and corrections during the treatment. The refinement of the absorbed dose values using calculations and direct dosimetry minimizes the risk of complications and ensures the possibility of effective use of other treatment methods, including photodynamic therapy, after CRT.


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