Blood pressure effects of CPAP in nonresistant and resistant hypertension associated with OSA: A systematic review of randomized clinical trials

Abstract BackgroundSystemic arterial hypertension (HTN) is the leading risk factor of cardiovascular disease death. Lifestyle changes are key for the prevention and management of HTN. Regular aerobic exercise training is recommended as part of the management of HTN; and dynamic resistance exercise should be prescribed as an adjuvant to aerobic training. Recent evidence points to potential benefits of isometric resistance training in reducing blood pressure (BP). Yet, the hypotensive effect of isometric exercise in pre-hypertensive and hypertensive individuals is not fully understood. Thus, we will examine the effect of isometric exercise in pre-hypertensive and hypertensive individuals through a systematic review and meta-analysis. MethodsOur systematic review study will include randomized clinical trials (RCTs) selected from the electronic databases MEDLINE (PubMed), Cochrane, LILACS, EMBASE and PEDro published in English, Spanish and Portuguese language. We will follow the PRISMA guidelines and PICOS framework. Our search will involve studies with both male and female participants aged 18 years or more diagnosed with prehypertension or HTN performing one session of isometric exercise (acute effect) or isometric exercise training (chronic effect) compared to a control group (no exercise). We will use Cochrane Risk of Bias 2 (RoB 2) tool to evaluate the quality of the studies and RStudio software (v1.3.959 for Windows) for statistical analyses. DiscussionA meta-analysis of a homogeneous sample of pre-hypertensive and hypertensive individuals involving isometric handgrip exercise alone can further support previous findings and improve our understanding and recommendations for the management of these populations. Systematic review registrationThe study protocol for this review was registered in the International Prospective Register of Systematic Reviews (PROSPERO) (CRD 42020213081).

Download Full-text

Blood pressure effects of obstructive sleep apnea treatment by continuous positive airway pressure: Systematic review, metaanalysis and evaluation of phenotypes predicting response

10.1183/13993003.congress-2019.pa4149 ◽

2019 ◽

Author(s):

Martino Pengo ◽

Davide Soranna ◽

Alice Giontella ◽

Elisa Perger ◽

Esther Schwarz ◽

...

Keyword(s):

Systematic Review ◽

Blood Pressure ◽

Obstructive Sleep Apnea ◽

Continuous Positive Airway Pressure ◽

Airway Pressure ◽

Positive Airway Pressure ◽

Pressure Effects ◽

Obstructive Sleep ◽

Blood Pressure Effects ◽

Sleep Apnea Treatment

Download Full-text

Effect of traditional resistance training on blood pressure in normotensive elderly persons: a systematic review of randomized controlled trials and meta-analyses

Revista Brasileira de Geriatria e Gerontologia ◽

10.1590/1981-22562017020.160181 ◽

2017 ◽

Vol 20 (4) ◽

pp. 571-581 ◽

Cited By ~ 2

Author(s):

Durcelina Schiavoni ◽

Ligia Maxwell Pereira ◽

Hugo Maxwell Pereira ◽

Edilson Serpeloni Cyrino ◽

Jefferson Rosa Cardoso

Keyword(s):

Systematic Review ◽

Blood Pressure ◽

Clinical Trials ◽

Resistance Training ◽

Randomized Clinical Trials ◽

Random Effect Model ◽

Control Group ◽

Elderly Persons ◽

Traditional Resistance Training ◽

Meta Analyses

Abstract The objective of the present study was to determine the effectiveness of the regular practice of traditional resistance training (RT) on systolic (SBP) and diastolic blood pressure (DBP) in normotensive elderly persons. A systematic review of randomized clinical trials and meta-analyses was performed. Searches were performed without language restrictions in different databases. Randomized clinical trials published from 1966 to 2010 that assessed the effects of traditional RT on resting blood pressure (BP) and/or for the treatment of high BP were included. Only studies that assessed the effects of traditional RT on elderly adults, regardless of the number of exercises, with the presence of a control group and comparisons between groups, were included. Twenty-nine studies were found, but only six met the inclusion criteria. The mean difference was used for meta-analysis, using a 95% confidence interval and a random effect model. Traditional RT induced a significant decrease in SBP (-6.63 mmHg; p=0.02) but not in DBP (-3.34 mmHg; p=0.11). These results suggest that traditional RT may be a non-pharmacological strategy for the control of BP in the elderly.

Download Full-text