Molecular Biology and Molecular Genetics of Nitric Oxide Synthase Genes

1996 ◽  
Vol 18 (2) ◽  
pp. 113-143 ◽  
Author(s):  
Spohie Nadaud ◽  
Florent Soubrier
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Molecular Biology ◽  
Molecular Genetics ◽  
Oxide Synthase

Nitric oxide Synthase: From Molecular Biology to Cerebrovascular Physiology

Physiology ◽  
1994 ◽  
Vol 9 (2) ◽  
pp. 64-64 ◽  
Author(s):  
ZS Katusic ◽  
F Cosentino
Keyword(s):  
Nitric Oxide ◽  
Smooth Muscle ◽  
Nitric Oxide Synthase ◽  
Molecular Biology ◽  
Smooth Muscle Cells ◽  
Arterial Wall ◽  
Perivascular Nerves ◽  
Oxide Synthase ◽  
Arterial Tone

Three distinct nitric oxide synthase genes are expressed in the cerebral arterial wall. Constitutive isoforms are localized in endothelium and perivascular nerves, whereas only inducible enzyme is present in smooth muscle cells, demonstrating the complex role of nitric oxide in regulation of cerebral arterial tone.

Localization of endothelial nitric oxide synthase in the normal and failing human atrial myocardium

1996 ◽  
Vol 54 ◽  
pp. 786-787
Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Cardiac Tissues ◽  
Mammalian Tissues ◽  
End Stage Heart Failure ◽  
End Stage ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).

Nitric oxide synthase and cellac disease

2001 ◽  
Vol 120 (5) ◽  
pp. A684-A684
Author(s):  
I DANIELS ◽  
I MURRAY ◽  
W GODDARD ◽  
R LONG
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Oxide Synthase

Inhibitory effect of melatonin on nitric oxide synthase in rat enteric nervous system

2001 ◽  
Vol 120 (5) ◽  
pp. A176-A176
Author(s):  
P KOPPITZ ◽  
M STORR ◽  
D SAUR ◽  
M KURJAK ◽  
H ALLESCHER
Keyword(s):  
Nitric Oxide ◽  
Nervous System ◽  
Nitric Oxide Synthase ◽  
Enteric Nervous System ◽  
Inhibitory Effect ◽  
Oxide Synthase
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