Polymeric micelles as a drug delivery system enhance cytotoxicity of vinorelbine through more intercellular accumulation

Drug Delivery ◽  
2010 ◽  
Vol 17 (4) ◽  
pp. 255-262 ◽  
Author(s):  
Xiaoyan Lu ◽  
Fayun Zhang ◽  
Lei Qin ◽  
Fengying Xiao ◽  
Wei Liang
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Polymeric Micelles

Antibacterial activities of polymeric poly(dl-lactide-co-glycolide) nanoparticles and Soluplus® micelles against Staphylococcus epidermidis biofilm and their characterization

RSC Advances ◽  
2015 ◽  
Vol 5 (88) ◽  
pp. 71709-71717 ◽  
Author(s):  
Chisato Takahashi ◽  
Shoko Saito ◽  
Asami Suda ◽  
Noriko Ogawa ◽  
Yoshiaki Kawashima ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Polyethylene Glycol ◽  
Drug Delivery System ◽  
Delivery System ◽  
Graft Copolymer ◽  
Staphylococcus Epidermidis ◽  
Polyvinyl Acetate ◽  
Polymeric Micelles ◽  
Antibacterial Activities

We have successfully prepared polymeric micelles based on polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol graft copolymer (Soluplus®) for a drug delivery system on a biofilm.

Polymeric micelles drug delivery system in oncology

2012 ◽  
Vol 159 (3) ◽  
pp. 312-323 ◽  
Author(s):  
Jian Gong ◽  
Meiwan Chen ◽  
Ying Zheng ◽  
Shengpeng Wang ◽  
Yitao Wang
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Polymeric Micelles

scholarly journals Comprehensive Review On Nanomicelles Drug Delivery System

2021 ◽  
Vol 001 (01) ◽  
Author(s):  
Meshva Patel ◽  
Ajay Solanki ◽  
Mamta Nasit
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Polymeric Micelles ◽  
Surfactant Micelles ◽  
Lipophilic Drug ◽  
Drug Molecules ◽  
Novel Drug ◽  
Poor Absorption ◽  
High Bioavailability

Many novel drug molecules in a clinical study as well as many existing drug molecules are lipophilic or hydrophobic in nature and thus they usually shows low bioavailability, poor absorption properties, low permeation as well as inability to reach at effective therapeutic concentration in blood. To overcome this problem, nanomicelles is the break through drug delivery system in which a lipophilic drug can be incorporated in polymeric micelles or surfactant micelles that can provide high solubility as well as high bioavailability. Due to the fact that Micelles have inner lipophilic core and outer hydrophilic shell as well as the inner lipophilic core provide space for incorporation for lipophilic drug, it enhances permeability of the lipophilic drug even at depth and also at target site. The present article provides overview of various applications of nanomicelles, it’s advantages as well as limitations, methods of preparations and various approaches for applications of nanomicelles.

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