Interaction of 68–kDa TAR RNA-binding protein and other cellular proteins with rpion protein-RNA stem-loop

1995 ◽  
Vol 1 (5-6) ◽  
pp. 391-398 ◽  
Author(s):  
Ute Scheffer ◽  
Takashi Okamoto ◽  
Jock MS Forrest ◽  
Peter G Rytik ◽  
Werner EG Müller ◽  
...  
Keyword(s):  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Cellular Proteins ◽  
Stem Loop ◽  
Tar Rna

scholarly journals Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR

Science ◽  
1991 ◽  
Vol 251 (5001) ◽  
pp. 1597-1600 ◽  
Author(s):  
A Gatignol ◽  
A Buckler-White ◽  
B Berkhout ◽  
K. Jeang
Keyword(s):  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Tar Rna ◽  
Hiv 1

scholarly journals The TAR-RNA binding protein is required for immunoresponses triggered by Cardiovirus infection

2016 ◽  
Vol 480 (2) ◽  
pp. 187-193 ◽  
Author(s):  
Akihiko Komuro ◽  
Yuya Homma ◽  
Takaharu Negoro ◽  
Glen N. Barber ◽  
Curt M. Horvath
Keyword(s):  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Tar Rna

scholarly journals The viral nucleocapsid protein and the human RNA-binding protein Mex3A promote translation of the Andes orthohantavirus small mRNA

2021 ◽  
Vol 17 (9) ◽  
pp. e1009931
Author(s):  
Jorge Vera-Otarola ◽  
Estefania Castillo-Vargas ◽  
Jenniffer Angulo ◽  
Francisco M. Barriga ◽  
Eduard Batlle ◽  
...  
Keyword(s):  
Nucleocapsid Protein ◽  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Initiation Factor ◽  
Cellular Proteins ◽  
Dependent Manner ◽  
The Andes ◽  
Viral Nucleocapsid

The capped Small segment mRNA (SmRNA) of the Andes orthohantavirus (ANDV) lacks a poly(A) tail. In this study, we characterize the mechanism driving ANDV-SmRNA translation. Results show that the ANDV-nucleocapsid protein (ANDV-N) promotes in vitro translation from capped mRNAs without replacing eukaryotic initiation factor (eIF) 4G. Using an RNA affinity chromatography approach followed by mass spectrometry, we identify the human RNA chaperone Mex3A (hMex3A) as a SmRNA-3’UTR binding protein. Results show that hMex3A enhances SmRNA translation in a 3’UTR dependent manner, either alone or when co-expressed with the ANDV-N. The ANDV-N and hMex3A proteins do not interact in cells, but both proteins interact with eIF4G. The hMex3A–eIF4G interaction showed to be independent of ANDV-infection or ANDV-N expression. Together, our observations suggest that translation of the ANDV SmRNA is enhanced by a 5’-3’ end interaction, mediated by both viral and cellular proteins.

Expression of TAR RNA-Binding Protein in Baculovirus and Co-Immunoprecipitation with Insect Cell Protein Kinase

1995 ◽  
Vol 2 (4) ◽  
pp. 322-329
Author(s):  
Edward D. Blair ◽  
Christopher M. Roberts ◽  
Wendy B. Snowden ◽  
Anne Gatignol ◽  
Monsef Benkirange ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Insect Cell ◽  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Cell Protein ◽  
Tar Rna

scholarly journals The TAR RNA-binding Protein, TRBP, Stimulates the Expression of TAR-containing RNAsin Vitroandin VivoIndependently of Its Ability to Inhibit the dsRNA-dependent Kinase PKR

2002 ◽  
Vol 278 (7) ◽  
pp. 4440-4448 ◽  
Author(s):  
Dominique Dorin ◽  
Marion C. Bonnet ◽  
Sylvie Bannwarth ◽  
Anne Gatignol ◽  
Eliane F. Meurs ◽  
...  
Keyword(s):  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Tar Rna

scholarly journals U6atac snRNA stem-loop interacts with U12 p65 RNA binding protein and is functionally interchangeable with the U12 apical stem-loop III

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Jagjit Singh ◽  
Kavleen Sikand ◽  
Heike Conrad ◽  
Cindy L. Will ◽  
Anton A. Komar ◽  
...  
Keyword(s):  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Stem Loop

scholarly journals Helical Defects in MicroRNA Influence Protein Binding by TAR RNA Binding Protein

PLoS ONE ◽  
2015 ◽  
Vol 10 (1) ◽  
pp. e0116749 ◽  
Author(s):  
Roderico Acevedo ◽  
Nichole Orench-Rivera ◽  
Kaycee A. Quarles ◽  
Scott A. Showalter
Keyword(s):  
Protein Binding ◽  
Rna Binding ◽  
Binding Protein ◽  
Rna Binding Protein ◽  
Tar Rna
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