Interrupted speech and MRI findings after traumatic head injury: A long-term follow-up

Intradiscal O2–O3 injections are conventionally used as a minimally invasive treatment for lumbar disc herniation in patients not responding to conservative treatments. The aim of the present study is to report data of long-term imaging follow-up (3 years) of patients treated with intradiscal O2–O3 lumbar chemiodiscolysis. We evaluated the changes of disc volume and the modifications in disc appearance (in terms of disc degeneration) and endplate changes (according to Modic), comparing the results with a control group of patients. Our results showed a stable reduction of the disc herniation volume in patients treated compared with the control group, while we did not find statistically significant differences in terms of disc degeneration and endplate changes (Modic). We concluded that the O2–O3 discolysis, despite leading to a significant shrinkage of the disc herniation, does not involve – in the long term – biomechanical changes of the spine in terms of acceleration of the disc degeneration process in comparison with the natural course.

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Correlation between neutrophil lymphocyte count ratio and outcomes of severe traumatic head injury

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20214873 ◽

2021 ◽

Vol 9 (1) ◽

pp. 10

Author(s):

Tamajyoti Ghosh ◽

Subir Dey

Keyword(s):

Traumatic Brain Injury ◽

Brain Injury ◽

Head Injury ◽

Severe Traumatic Brain Injury ◽

Univariate Analysis ◽

P Value ◽

Traumatic Head Injury ◽

Neutrophil Lymphocyte Ratio ◽

Traumatic Head

Background: Raised peripheral neutrophil lymphocyte ratio is associated with poorer outcomes in conditions such as severe brain injury, ICH, cardiovascular conditions, cancer.Methods: Retrospective analysis of 96 severe Traumatic Brain injury data treated at our institute over a period of 1 year. The patients were followed up for a period of at least 1 month. The primary outcome of the study was 1 month GOS and the various variables which may be associated with the poor GOS at 1 month follow up. Model based analysis was done for NLCR <24 hrs at 48 hrs and GCS at the time of presentation and discriminative ability of the models were studied by the Area under the curve.Results: Univariate analysis were done of 96 patients of severe traumatic brain injury for various variables such as age, sex, mode of head injury, type of head injury, presenting GCS and NLCR at 24 hrs and 48 hrs to that of GOS at 1 month follow up. Initial GCS <7 (p=0.0138) with AUC=0.6689 and peak NLCR (<24 hr) of > 9.6 (AUC=0.931) with a p value of <0.001 with sensitivity of 100% and specificity of 79.27% and peak NLCR (48 hrs) of >12.4 (AUC= 0.973) with a p value of <0.001 with sensitivity of 100% and specificity of 89.02% were associated with unfavourable outcome.Conclusions: High NLCR and initial poor GCS are independent unfavourable prognostic factors in 1 month GOS following severe traumatic head injury.

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Pyridoxine-dependent Seizures: Long-term Follow-up of Two Cases with Clinical and MRI Findings, and Pyridoxine Treatment

Journal of Tropical Pediatrics ◽

10.1093/tropej/48.5.303 ◽

2002 ◽

Vol 48 (5) ◽

pp. 303-306 ◽

Cited By ~ 7

Author(s):

H. Ulvi

Keyword(s):

Mri Findings ◽

Long Term Follow Up

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Frühdiagnostik des Morbus Perthes: Wertigkeit von Skelettszintigraphie und Kernspintomographie im Vergleich zu Röntgenbefunden

Nuklearmedizin ◽

10.1055/s-0038-1629585 ◽

1991 ◽

Vol 30 (06) ◽

pp. 265-271 ◽

Cited By ~ 3

Author(s):

J. Rütt ◽

A. Linden ◽

Kamilla Smolarz ◽

E. Voth ◽

H. Schicha ◽

...

Keyword(s):

Bone Scintigraphy ◽

Resonance Imaging ◽

Radiological Findings ◽

Mri Findings ◽

Long Term Follow Up ◽

Magnetic Resonance Imaging Mri ◽

Conventional Radiology ◽

Initial Results

The value of conventional radiology, bone scintigraphy and magnetic resonance imaging (MRI) in the early diagnosis of Legg-Calvé-Perthes disease (LCPD) was assessed. The initial results were compared with the clinical and radiological findings of long-term follow-up in 43 children. Radiological and scintigraphic examination resulted in a relatively high number of equivocal findings (16% and 10%, respectively). MRI findings were less equivocal (3%). Depending on whether such findings were classified as normal or as pathological, the diagnostic accuracy ranged as follows: radiography 88–93%, bone scintigraphy 88-91%, and MRI 97–99%. Therefore, MRI by itself seems to be sufficient to detect or exclude LCPD. The results of this study and the radiation exposure associated with radiography and scintigraphy raise the question whether MRI should be the diagnostic method of choice in patients with suspected LCPD.

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