FORMATION OF SYSTEMIC MANIFESTATIONS AND DEFINITION OF PROGRESSION PREDICTORS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE USING A FACTOR ANALYSIS

2019 ◽  
Vol 103 (1) ◽  
pp. 49-54
Author(s):  
L. D. Todoriko
Author(s):  
John J. Reilly

Virtually every health care practitioner who provides care to adults will encounter individuals with chronic obstructive pulmonary disease (COPD). Current estimates of the prevalence of the condition vary based on the method of ascertainment: most surveys show that approximately 6% of adults report a doctor's diagnosis of COPD but that approximately 25% have airflow obstruction when assessed by spirometry. COPD is common, morbid, mortal, and expensive: estimates are that 〉20 million U.S. adults have COPD and that it is responsible for 〉120,000 deaths annually with a cost to the U.S. economy of more than $38 billion. This chapter describes the definition of COPD, presenting clinical symptomatology and evaluation, natural history, differential diagnosis, current concepts of pathogenesis, therapeutic options, and the evaluation of a patient with known or suspected COPD considering surgery.


Medicina ◽  
2019 ◽  
Vol 55 (10) ◽  
pp. 646
Author(s):  
Vazquez Guillamet

Chronic obstructive pulmonary disease (COPD) accounts for the largest proportion ofrespiratory deaths worldwide and was historically the leading indication for lung transplantation.The success of lung transplantation procedures is measured as survival benefit, calculated assurvival with transplantation minus predicted survival without transplantation. In chronicobstructive pulmonary disease, it is difficult to show a clear and consistent survival benefit.Increasing knowledge of the risk factors, phenotypical heterogeneity, systemic manifestations, andtheir management helps improve our ability to select candidates and list those that will benefit themost from the procedure.


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