TERKAIT DENGAN MASA MASA PANDEMI COVID-19 DILAKUKANNYA KESIMBANGAN DENGAN PENCEGAHAN DAN MENINGKATKAN KESELAMATAN PASIEN RAWAT INAP

Virus Rna ◽

Coronavirus adalah virus RNA dengan ukuran partikel 120-160 nm. Virus ini utamanya menginfeksi hewan, di antaranya adalah kelelawar dan unta. Sebelum terjadinya wabah COVID-19, ada 6 jenis coronavirus yang dapat menginfeksi manusia, yaitu alphacoronavirus 229E, alphacoronavirus NL63, betacoronavirus OC43, betacoronavirus HKU1, Severe Acute Respiratory Illness Coronavirus (SARS-CoV), dan Middle East Respiratory Syndrome Coronavirus (MERS-CoV).Coronavirus yang menjadi etiologi COVID-19 termasuk dalam genus betacoronavirus. Hasil analisis filogenetik menunjukkan bahwa virus ini masuk dalam subgenus yang sama dengan coronavirus yang menyebabkan wabah Severe Acute Respiratory Illness (SARS) pada 2002-2004 silam, yaitu Sarbecovirus. Atas dasar ini, International Committee on Taxonomy of Viruses mengajukan nama SARS-CoV-2.

Middle East respiratory syndrome coronavirus not detected in children hospitalized with acute respiratory illness in Amman, Jordan, March 2010 to September 2012

Clinical Microbiology and Infection ◽

10.1111/1469-0691.12438 ◽

2014 ◽

Vol 20 (7) ◽

pp. 678-682 ◽

Cited By ~ 8

Author(s):

N. Khuri-Bulos ◽

D.C. Payne ◽

X. Lu ◽

D. Erdman ◽

L. Wang ◽

...

Keyword(s):

Middle East ◽

Respiratory Illness ◽

Middle East Respiratory Syndrome ◽

Acute Respiratory Illness

Comparison of severe acute respiratory illness (sari) and clinical pneumonia case definitions for the detection of influenza virus infections among hospitalized patients, western Kenya, 2009‐2013

Influenza and Other Respiratory Viruses ◽

10.1111/irv.12382 ◽

2016 ◽

Vol 10 (4) ◽

pp. 333-339 ◽

Cited By ~ 7

Author(s):

Caroline Makokha ◽

Joshua Mott ◽

Henry N. Njuguna ◽

Sammy Khagayi ◽

Jennifer R. Verani ◽

...

Keyword(s):

Influenza Virus ◽

Respiratory Illness ◽

Hospitalized Patients ◽

Virus Infections ◽

Case Definitions ◽

Western Kenya ◽

Pneumonia Case ◽

Viral and bacterial etiology of severe acute respiratory illness among children < 5 years of age without influenza in Niger

BMC Infectious Diseases ◽

10.1186/s12879-015-1251-y ◽

2015 ◽

Vol 15 (1) ◽

Cited By ~ 13

Author(s):

Adamou Lagare ◽

Halima Boubacar Maïnassara ◽

Bassira Issaka ◽

Ali Sidiki ◽

Stefano Tempia

Keyword(s):

Respiratory Illness ◽

A case report of the enterovirus-D68 associated severe acute respiratory illness in a pediatric case from India

Journal of Infection and Public Health ◽

10.1016/j.jiph.2019.04.013 ◽

2019 ◽

Vol 12 (6) ◽

pp. 900-903

Author(s):

Sumit D. Bhardwaj ◽

Varsha A. Potdar ◽

Pragya D. Yadav ◽

Manohar L. Chaudhary ◽

Mandeep S. Chadha ◽

...

Keyword(s):

Case Report ◽

Respiratory Illness ◽

Pediatric Case ◽

Enterovirus D68 ◽

Use of clinical frailty scale in acute care settings as a predictor of in-hospital and short-term mortality in older adults with severe acute respiratory illness: A prospective pilot cohort study from India

Journal of the Indian Academy of Geriatrics ◽

10.4103/jiag.jiag_25_21 ◽

2021 ◽

Vol 17 (3) ◽

pp. 89

Author(s):

Sunny Singhal ◽

Pramod Kumar ◽

Akshata Rao ◽

Sunil Jyani ◽

Nayer Jamshed ◽

...

Keyword(s):

Older Adults ◽

Cohort Study ◽

Acute Care ◽

Respiratory Illness ◽

Short Term ◽

Clinical Frailty Scale ◽

Short Term Mortality ◽

Acute Care Settings ◽

Estimated Direct Costs of Patients Hospitalized for Severe Acute Respiratory Illness in the Mexican Social Security Institute. Winter Season, 2013-2014

Internal Medicine Open Access ◽

10.4172/2165-8048.1000180 ◽

2015 ◽

Vol 05 (01) ◽

Author(s):

David Alejandro Cabrera Gaytan

Keyword(s):

Social Security ◽

Winter Season ◽

Respiratory Illness ◽

Direct Costs ◽

Social Security Institute ◽

Structure and oligomerization state of the C-terminal region of the Middle East respiratory syndrome coronavirus nucleoprotein

Acta Crystallographica Section D Structural Biology ◽

10.1107/s2059798318014948 ◽

2019 ◽

Vol 75 (1) ◽

pp. 8-15 ◽

Cited By ~ 7

Author(s):

Thi Hong Van Nguyen ◽

Julie Lichière ◽

Bruno Canard ◽

Nicolas Papageorgiou ◽

Sarah Attoumani ◽

...

Keyword(s):

Middle East ◽

Structural Information ◽

Respiratory Illness ◽

Middle East Respiratory Syndrome ◽

X Ray Diffraction ◽

X Ray ◽

X Ray Scattering ◽

Nucleoprotein N ◽

High Degree ◽

Genome Encapsidation

Middle East respiratory syndrome coronavirus (MERS-CoV) is a human pathogen responsible for a severe respiratory illness that emerged in 2012. Structural information about the proteins that constitute the viral particle is scarce. In order to contribute to a better understanding of the nucleoprotein (N) in charge of RNA genome encapsidation, the structure of the C-terminal domain of N from MERS-CoV obtained using single-crystal X-ray diffraction is reported here at 1.97 Å resolution. The molecule is present as a dimer in the crystal structure and this oligomerization state is confirmed in solution, as measured by additional methods including small-angle X-ray scattering measurements. Comparisons with the structures of the C-terminal domains of N from other coronaviruses reveals a high degree of structural conservation despite low sequence conservation, and differences in electrostatic potential at the surface of the protein.