scholarly journals 3D-printed rotating spinnerets create membranes with a twist

2019 ◽  
Author(s):  
Matthias Wessling

Round hollow fiber membranes have been well established in applications such as gas separation, ultrafiltration and blood dialysis. Yet, it is well known that geometrical topologies can introduce secondary flow patterns counteracting mass transport limitations, stemming from diffusion resistances and fouling. We present a new systematic methodology to fabricate novel membrane architectures. We use the freedom of design by 3D-printing spinnerets, having multiple bore channels of any geometry. First, such spinnerets are stationary to fabricate straight bore channels inside a monolithic membrane. Second, in an even more complex design, a new mechanical system enables rotating the spinneret. Such rotating multibore spinnerets enable (A) the preparation of twisted channels inside a porous monolithic membrane as well as (B) a helical twist of the outside geometry. The spun material systems comprise classical polymer solutions as well as metal-polymer slurries resulting in solid porous metallic monolithic membrane after thermal post-processing. It is known that twisted spiral-type bore channel geometries are potentially superior to straight channels with respect to mass and heat polarization phenomena, however their fabrication was cumbersome in the past. Now, the described methodology enables membrane fabrication to tailor the membrane geometry to the needs of the membrane process. To showcase the delicate interplay between the geometry and radial and axial flow conditions, we report fluid mechanical simulations and flow magnetic resonance imaging measurements for a twisted tri-bore membrane during permeation.

Pharmaceutics ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 1207
Author(s):  
Andrea Vítečková Wünschová ◽  
Adam Novobilský ◽  
Jana Hložková ◽  
Peter Scheer ◽  
Hana Petroková ◽  
...  

Diseases with the highest burden for society such as stroke, myocardial infarction, pulmonary embolism, and others are due to blood clots. Preclinical and clinical techniques to study blood clots are important tools for translational research of new diagnostic and therapeutic modalities that target blood clots. In this study, we employed a three-dimensional (3D) printed middle cerebral artery model to image clots under flow conditions using preclinical imaging techniques including fluorescent whole-body imaging, magnetic resonance imaging (MRI), and computed X-ray microtomography (microCT). Both liposome-based, fibrin-targeted, and non-targeted contrast agents were proven to provide a sufficient signal for clot imaging within the model under flow conditions. The application of the model for clot targeting studies and thrombolytic studies using preclinical imaging techniques is shown here. For the first time, a novel method of thrombus labeling utilizing barium sulphate (Micropaque®) is presented here as an example of successfully employed contrast agents for in vitro experiments evaluating the time-course of thrombolysis and thus the efficacy of a thrombolytic drug, recombinant tissue plasminogen activator (rtPA). Finally, the proof-of-concept of in vivo clot imaging in a middle cerebral artery occlusion (MCAO) rat model using barium sulphate-labelled clots is presented, confirming the great potential of such an approach to make experiments comparable between in vitro and in vivo models, finally leading to a reduction in animals needed.


2010 ◽  
Vol 132 (2) ◽  
Author(s):  
Nobuyuki Yamaguchi ◽  
Masayuki Ogata ◽  
Yohei Kato

An improved construction of air-separator device, which has radial-vanes embedded within its inlet circumferential opening with their leading-edges facing the moving tips of the fan rotor-blades so as to scoop the tip flow, was investigated with respect to the stall-prevention effect on a low-speed, single-stage, lightly loaded, axial-flow fan. Stall-prevention effects by the separator layout, relative location of the separator to the rotor-blades, and widths of the openings of the air-separator inlet and exit were parametrically surveyed. As far as the particular fan is concerned, the device together with the best relative location has proved to be able to eliminate effectively the stall zone having existed in the original solid-wall characteristics, which has confirmed the promising potential of the device. Guidelines were obtained from the data for optimizing relative locations of the device to the rotor-blades, maximizing the stall-prevention effect of the device, and minimizing the axial size of the device for a required stall-prevention effect, at least for the particular fan and possibly for fans of similar light-load fans. The data suggest the changing internal flow conditions affected by the device conditions.


2018 ◽  
Vol 5 (1) ◽  
pp. 1526458
Author(s):  
G Srinivas ◽  
K Raghunandana ◽  
Shenoy B Satish ◽  
Duc Pham

Author(s):  
Tiffaney Flaata ◽  
Gregory J. Michna ◽  
Todd Letcher

Additive manufacturing, the layer-by-layer creation of parts, was initially used for rapid prototyping of new designs. Recently, due to the decrease in the cost and increase in the resolution and strength of additively manufactured parts, additive manufacturing is increasingly being used for production of parts for end-use applications. Fused Deposition Modeling (FDM), a type of 3d printing, is a process of additive manufacturing in which a molten thermoplastic material is extruded to create the desired geometry. Many potential heat transfer applications of 3d printed parts, including the development of additively manufactured heat exchangers, exist. In addition, the availability of metal/polymer composite filaments, first used for applications such as tooling for injection molding applications and to improve wear resistance, could lead to increased performance 3d printed heat exchangers because of the higher thermal conductivity of the material. However, the exploitation of 3d printing for heat transfer applications is hindered by a lack of reliable thermal conductivity data for as-printed materials, which typically include significant void fractions. In this experimental study, an apparatus to measure the effective thermal conductivity of 3d printed composite materials was designed and fabricated. Its ability to accurately measure the thermal conductivity of polymers was validated using a sample of acrylic, whose conductivity is well understood. Finally, the thermal conductivities of various 3d printed polymer, metal/polymer composite, and carbon/polymer composite filaments were measured and are reported in this paper. The materials used are acrylonitrile butadiene styrene (ABS), polylactic acid (PLA), stainless steel/PLA, Brass/PLA, and Bronze/PLA.


Author(s):  
Norun Abdul Malek ◽  
Athirah Mohd Ramly ◽  
Atiah Sidek ◽  
Sarah Yasmin Mohamad

<p>3D printing is one of the additive manufacturing technology that has gain popularity for time saving and complex design. This technology increases a degree of flexibility for potential 3D RF applications such as wearable and conformal antennas. This paper demonstrates a circular patch antenna fabricated on 3D printed Acrylonitrile Butadiene Styrene (ABS) filament. The main reason of using a 3D printer is that it is accurate, easy to fabricate of a complex geometry and the ability to create new antennas that cannot be made using conventional fabrication techniques. The ABS material has a tangent loss of 0.0051 and the relative permittivity is 2.74. The thickness of the substrate is 1.25 mm. The simulation has been performed using Computer Simulation Technology (CST). The return loss from simulation software is in good match with measurement which is 12.5dB at 2.44GHz. Hence, from the results obtained, the ABS could be used as a substrate for an antenna.</p>


Author(s):  
Chiara Palomba

Rotating stall is an instability phenomenon that arises in axial flow compressors when the flow is reduced at constant rotational speed. It is characterised by the onset of rotating perturbations in the flow field accompanied by either an abrupt or gradual decrease of performances. Although the flow field is unsteady and non axisymmetric, the global operating point is stable and a stalled branch of performance curve may be experimentally determined. The number, rotational speed, circumferential extension of the rotating perturbed flow regions named rotating cells may vary from one compressor to another and may depend on the throttle position. The present work focuses on the interaction between local flow parameters and global compressor performance parameters with the aim of reaching a better understanding of the phenomenon. Starting from the Day, Greitzer and Cumpsty [1] model the detailed flow conditions during rotating stall are studied and related to the global performance parameters. This is done both to verify if the compressor under examination fits to the model and if the detailed flow structure may highlight the physics that in the simple model may hide behind the correlation’s used.


Author(s):  
Donato M. Palermo ◽  
Feng Gao ◽  
John W. Chew ◽  
Paul F. Beard

Abstract A systematic study of sealing performance for a chute style turbine rim seal using URANS methods is reported. This extends previous studies from a configuration without external flow in the main annulus to cases with a circumferentially uniform axial flow and vane generated swirling annulus flow (but without rotor blades). The study includes variation of the mean seal-to-rotor velocity ratio, main annulus-to-rotor velocity ratio, and seal clearance. The effects on the unsteady flow structures and the degree of main annulus flow ingestion into the rim seal cavity are examined. Sealing effectiveness is quantified by modeling a passive scalar, and the timescales for the convergence of this solution are considered. It has been found that intrinsic flow unsteadiness occurs in most cases, with the presence of vanes and external flow modifying, the associated flow structures and frequencies. Some sensitivities to the annulus flow conditions are identified. The circumferential pressure asymmetry generated by the vanes has a clear influence on the flow structure but does not lead to higher ingestion rates than the other conditions studied.


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