scholarly journals Recognition Memory Shielded from Semantic but not Perceptual Interference in Normal Aging

2018 ◽  
Author(s):  
D. Merika Wilson ◽  
Kevin Potter ◽  
Rosemary Cowell
Keyword(s):  
Young Adults ◽  
Recognition Memory ◽  
Memory Task ◽  
Memory Loss ◽  
Normal Aging ◽  
Related Word ◽  
Category Size ◽  
Perceptual Features ◽  
Perceptual Interference ◽  
Age Related

Normal aging impairs long-term declarative memory, and evidence suggests that this impairment may be driven partly by structural or functional changes in the medial temporal lobe (MTL). Theories of MTL memory function therefore make predictions for age-related memory loss. One theory – the Representational-Hierarchical account – makes two specific predictions. First, recognition memory in older participants should be impaired by feature-level interference, in which studied items contain many shared perceptual features such that those features appear repeatedly. Second, if the interference in a recognition memory task – i.e., the information that repeats across items – resides at a higher level of complexity than simple perceptual features, such as semantic gist, older adults should be less impacted by such interference than young adults. We tested these predictions using the Deese-Roediger-McDermott paradigm, by creating feature-level (i.e., perceptual) interference with phonemically/orthographically related word categories, and higher-level associative interference with semantically related word categories. Importantly, we manipulated category size in order to compare the effect of less versus more interference (i.e., small versus large category size), which served to (1) avoid potential item confounds arising from systematic differences between words belonging to perceptually- versus semantically-related categories, and (2) ensure that any effect of interference was due to information encoded at study, rather than pre-experimentally. Further, we used signal detection theory to interpret our data, rather than examining false alarm rates in isolation, thereby avoiding potentially confounding contamination of the memory measure by changes in response bias across conditions or groups. Older participants, relative to young adults, were relatively more impaired by perceptual interference and less impaired by semantic interference. This pattern seems at odds with many current theories of age-related memory loss, but is in line with the Representational-Hierarchical account.

Mechanism of Sequential Swallowing During Straw Drinking in Healthy Young and Older Adults

2004 ◽  
Vol 47 (1) ◽  
pp. 33-45 ◽  
Author(s):  
Stephanie K. Daniels ◽  
David M. Corey ◽  
Leslie D. Hadskey ◽  
Calli Legendre ◽  
Daniel H. Priestly ◽  
...  
Keyword(s):  
Older Adults ◽  
Young Adults ◽  
Movement Patterns ◽  
Leading Edge ◽  
Normal Aging ◽  
Significant Relation ◽  
Age Related ◽  
Laryngeal Penetration ◽  
Airway Invasion ◽  
Edge Location

Recent research has revealed differences between isolated and sequential swallowing in healthy young adults; however, the influence of normal aging on sequential swallowing has not been studied. Thus, the purpose of this investigation was to examine the effects of normal aging on deglutition during sequential straw drinking. Videofluoroscopic samples of two 10-s straw drinking trials were obtained for 20 healthy young men (age 29±3 years) and 18 healthy older men (age 69±7 years). Hyolaryngeal complex (HLC) movement patterns, leading edge of the bolus location at swallow onset, and occurrences of airway invasion were determined. Two HLC patterns were identified: (a) HLC lowering with the epiglottis returned to upright between swallows and (b) partially maintained HLC elevation with the epiglottis inverted between swallows. The bolus was frequently in the hypopharynx at swallow onset. Strong associations were identified between age and HLC pattern, age and leading edge of the bolus location, and HLC pattern and leading edge location. Laryngeal penetration was uncommon overall; however, it occurred more frequently in the older adults than in the young adults. A significant relation was identified between age and the average Penetration-Aspiration Scale score. Laryngeal penetration was associated with both HLC movement patterns and hypopharyngeal bolus location, particularly in older adults. Results indicate that subtle age-related differences are evident in healthy young and older adults with sequential straw drinking. These data suggest that specific inherent swallowing patterns may increase the risk of laryngeal penetration with normal aging.

scholarly journals Age-related Differences in Brain Activity during True and False Memory Retrieval

2008 ◽  
Vol 20 (8) ◽  
pp. 1390-1402 ◽  
Author(s):  
Nancy A. Dennis ◽  
Hongkeun Kim ◽  
Roberto Cabeza
Keyword(s):  
Older Adults ◽  
Young Adults ◽  
False Memory ◽  
Semantic Processing ◽  
Temporal Cortex ◽  
Memory Task ◽  
False Memories ◽  
Recognition Task ◽  
Retrosplenial Cortex ◽  
Age Related

Compared to young adults, older adults show not only a reduction in true memories but also an increase in false memories. We investigated the neural bases of these age effects using functional magnetic resonance imaging and a false memory task that resembles the Deese–Roediger–McDermott (DRM) paradigm. Young and older participants were scanned during a word recognition task that included studied words and new words that were strongly associated with studied words (critical lures). During correct recognition of studied words (true memory), older adults showed weaker activity than young adults in the hippocampus but stronger activity than young adults in the retrosplenial cortex. The hippocampal reduction is consistent with age-related deficits in recollection, whereas the retrosplenial increase suggests compensatory recruitment of alternative recollection-related regions. During incorrect recognition of critical lures (false memory), older adults displayed stronger activity than young adults in the left lateral temporal cortex, a region involved in semantic processing and semantic gist. Taken together, the results suggest that older adults' deficits in true memories reflect a decline in recollection processes mediated by the hippocampus, whereas their increased tendency to have false memories reflects their reliance on semantic gist mediated by the lateral temporal cortex.

scholarly journals On the Tip-of-the-Tongue: Neural Correlates of Increased Word-finding Failures in Normal Aging

2007 ◽  
Vol 19 (12) ◽  
pp. 2060-2070 ◽  
Author(s):  
Meredith A. Shafto ◽  
Deborah M. Burke ◽  
Emmanuel A. Stamatakis ◽  
Phyllis P. Tam ◽  
Lorraine K. Tyler
Keyword(s):  
Gray Matter ◽  
Neural Correlates ◽  
Normal Aging ◽  
Matter Density ◽  
Related Word ◽  
Gray Matter Density ◽  
Word Finding ◽  
Age Related ◽  
Tip Of The Tongue ◽  
Left Insula

Tip-of-the-tongue (TOT) experiences are frustrating word-finding failures where people are temporarily unable to produce a word they are certain they know. TOT frequency increases with normal aging during adulthood, and behavioral evidence suggests that the underlying deficit is in retrieving the complete phonology of the target word during production. The present study investigated the neural correlates of this phonological retrieval deficit. We obtained 3-D T1-weighted structural magnetic resonance images (MRI) for healthy participants between 19 and 88 years old and used voxel-based morphometry to measure gray matter density throughout the brain. In a separate session, participants named celebrities cued by pictures and descriptions, indicating when they had a TOT, and also completed Raven's Progressive Matrices (RPM), a task that does not involve phonological production. The number of TOTs increased with age and also with gray matter atrophy in the left insula, an area implicated in phonological production. The relation between TOTs and left insula atrophy cannot be attributed to the correlation of each variable with age because TOTs were related to insula atrophy even with age effects removed. Moreover, errors on the RPM increased with age, but performance did not correlate with gray matter density in the insula. These results provide, for the first time, an association between a region in the neural language system and the rise in age-related word-finding failures and suggest that age-related atrophy in neural regions important for phonological production may contribute to age-related word production failures.

scholarly journals Effects of Age on the Neural Correlates of Familiarity as Indexed by ERPs

2012 ◽  
Vol 24 (5) ◽  
pp. 1055-1068 ◽  
Author(s):  
Tracy H. Wang ◽  
Marianne de Chastelaine ◽  
Brian Minton ◽  
Michael D. Rugg
Keyword(s):  
Young Adults ◽  
Recognition Memory ◽  
Recognition Performance ◽  
Age Groups ◽  
Neural Correlates ◽  
Recognition Memory Test ◽  
Test Items ◽  
Related Difference ◽  
Age Related ◽  
Memory Signals

ERPs were recorded from samples of young (18–29 years) and older (63–77 years) participants while they performed a modified “remember–know” recognition memory test. ERP correlates of familiarity-driven recognition were obtained by contrasting the waveforms elicited by unrecollected test items accorded “confident old” and “confident new” judgments. Correlates of recollection were identified by contrasting the ERPs elicited by items accorded “remember” and confident old judgments. Behavioral analyses revealed lower estimates of both recollection and familiarity in older participants than in young participants. The putative ERP correlate of recollection—the “left parietal old–new effect”—was evident in both age groups, although it was slightly but significantly smaller in the older sample. By contrast, the putative ERP correlate of familiarity—the “midfrontal old–new effect”—could be identified in young participants only. This age-related difference in the sensitivity of ERPs to familiarity was also evident in subgroups of young and older participants, in whom familiarity-based recognition performance was equivalent. Thus, the inability to detect a reliable midfrontal old–new effect in older participants was not a consequence of an age-related decline in the strength of familiarity. These findings raise the possibility that familiarity-based recognition memory depends upon qualitatively different memory signals in older and young adults.

scholarly journals Recognition memory shielded from semantic but not perceptual interference in normal aging

2018 ◽  
Vol 119 ◽  
pp. 448-463 ◽  
Author(s):  
D. Merika Wilson ◽  
Kevin W. Potter ◽  
Rosemary A. Cowell
Keyword(s):  
Recognition Memory ◽  
Normal Aging ◽  
Perceptual Interference

Map Learning in Normal Aging: The Role of Individual Visuo-Spatial Abilities and Implications

2018 ◽  
Vol 15 (3) ◽  
pp. 205-218 ◽  
Author(s):  
Chiara Meneghetti ◽  
Veronica Muffato ◽  
Erika Borella ◽  
Rossana De Beni
Keyword(s):  
Young Adults ◽  
Spatial Working Memory ◽  
Age Groups ◽  
Normal Aging ◽  
Map Learning ◽  
Age Related ◽  
Pointing Task ◽  
Young Old ◽  
Sketch Map

Objective: The present study analyzes the age-related differences in map learning between young and normally-aging young-old and old-old adults in relation to individual visuo-spatial factors to specify which aspects of spatial learning are susceptible to aging. Methods: Forty young, 40 young-old and 40 old-old participants performed a series of tasks to assess their visuo-spatial working memory (VSWM) and visuo-spatial (rotation) abilities, then they studied a map. To test their recall, they graphically reproduced the map in a freehand drawing, then performed a sketch map task (which involved placing a list of landmarks on a blank layout of the map) and a pointing task (adopting aligned and counter-aligned imaginary positions). Results: The results showed that age-related differences depend on the type of recall task performed: in the pointing and freehand map-drawing tasks, the young-old and old-old performed worse than the young adults; but in the sketch map task, the young-old performed as well as the young adults and only the old-old’s performance was worse than that of the other two age groups. Concerning the role of individual factors, VSWM and rotation abilities were found strongly involved in the pointing task (especially for counter-aligned pointing) and the freehand map-drawing task. Conclusion: Overall, these results suggest that different factors related to spatial (map) learning explain age-related differences in normal aging. The implications of the present results in normal and pathological aging, and for the purposes of clinical assessments and interventions, are discussed.

scholarly journals Response bias and aging on a recognition memory task

2006 ◽  
Vol 12 (1) ◽  
pp. 1-7 ◽  
Author(s):  
TERRI J. HUH ◽  
JOEL H. KRAMER ◽  
ADAM GAZZALEY ◽  
DEAN C. DELIS
Keyword(s):  
Recognition Memory ◽  
Frontal Lobe ◽  
Response Bias ◽  
Verbal Learning ◽  
Memory Task ◽  
Underlying Mechanism ◽  
California Verbal Learning Test ◽  
Cognitive Changes ◽  
Age Related ◽  
Mediate Response

Response bias reflects the decision rule an individual uses when faced with uncertainty on recognition memory tasks. Recent studies indicate frontal regions may mediate response bias performance. One theory of aging also implicates frontal lobe contributions in age-related cognitive changes. This suggests that frontal lobe changes may mediate response bias in older adults. Consistent with this frontal aging hypothesis, we predicted that response bias would become more liberal with age. Methods: Participants were 181 younger (30–49) and 112 older normal adults (75+) that were part of the California Verbal Learning Test-second edition (CVLT-2) normative sample (total n = 1078). We used parametric measures of discriminability and response bias provided by the CVLT-2 scoring program. Groups were similar in IQ and education. Multi-level regression models were created to examine the effects of moderating variables. The interaction between age and age group significantly predicted response bias. Post hoc analysis indicated that increasing age was associated with more liberal bias in the older but not in the younger group. In the light of reported relationships between frontal regions and both aging and response bias, we hypothesize that frontal changes may be the underlying mechanism explaining the increase in liberal response bias with age. (JINS, 2006, 12, 1–7.)

scholarly journals Evidence for an Age-Related Positivity Effect in Metacognitive Confidence Judgments

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 363-364
Author(s):  
Edie Sanders ◽  
Jane Berry
Keyword(s):  
Recognition Memory ◽  
Age Differences ◽  
Cognitive Biases ◽  
Memory Task ◽  
Judgments Of Learning ◽  
Memory Biases ◽  
Positivity Effect ◽  
Older Adulthood ◽  
Age Related ◽  
Memory Monitoring

Abstract We examined age differences in metacognitive monitoring of emotionally-valenced stimuli. If older adults (OAs) are more focused on emotionally meaningful goals in late life (Carstensen, 2006), then they should demonstrate attentional and memory biases for positive stimuli over neutral and negative stimuli and, arguably, these cognitive biases should be reflected in their metacognitive judgments of learning. Judgments of learning (JOLs) for memory of positive, negative, and neutral words were collected. Younger adults (YAs) aged 18-23 years and OAs aged 65-90 years (N = 85) studied words in each valence category and made immediate JOLs, followed by a two-alternative forced choice (2AFC) recognition memory task. Analyses of JOLs revealed evidence for a positivity effect (Mather & Carstensen, 2005) in metacognitive confidence for OAs and an emotional salience effect in YAs (Tauber & Dunlosky, 2012; Zimmerman & Kelley, 2010). Predictably, YAs recognized more words than OAs, but valence did not affect number of words recognized and valence did not moderate age differences in recognition memory (p = .055). Memory monitoring as measured by resolution accuracy was equivalent in YAs and OAs (Hertzog & Dunlosky, 2011). Positive affect was higher and negative affect was lower in OAs relative to YAs (Gallant, Spaniol, & Yang, 2019), lending additional evidence to an orientation toward the positive in older adulthood. These results are novel in that they demonstrate an age-related positivity effect that extends beyond the domains of memory and emotion to the domain of metacognitive aging. Discussion will focus on theoretical, methodological, and applied implications.

Inefficient Encoding as an Explanation for Age-Related Deficits in Recollection-Based Processing

2014 ◽  
Vol 28 (3) ◽  
pp. 148-161 ◽  
Author(s):  
David Friedman ◽  
Ray Johnson
Keyword(s):  
Older Adults ◽  
Young Adults ◽  
Cognitive Processes ◽  
Brain Activity ◽  
Memory Performance ◽  
Brain Regions ◽  
Semantic Retrieval ◽  
Age Related ◽  
The Face ◽  
Episodic Memories

A cardinal feature of aging is a decline in episodic memory (EM). Nevertheless, there is evidence that some older adults may be able to “compensate” for failures in recollection-based processing by recruiting brain regions and cognitive processes not normally recruited by the young. We review the evidence suggesting that age-related declines in EM performance and recollection-related brain activity (left-parietal EM effect; LPEM) are due to altered processing at encoding. We describe results from our laboratory on differences in encoding- and retrieval-related activity between young and older adults. We then show that, relative to the young, in older adults brain activity at encoding is reduced over a brain region believed to be crucial for successful semantic elaboration in a 400–1,400-ms interval (left inferior prefrontal cortex, LIPFC; Johnson, Nessler, & Friedman, 2013 ; Nessler, Friedman, Johnson, & Bersick, 2007 ; Nessler, Johnson, Bersick, & Friedman, 2006 ). This reduced brain activity is associated with diminished subsequent recognition-memory performance and the LPEM at retrieval. We provide evidence for this premise by demonstrating that disrupting encoding-related processes during this 400–1,400-ms interval in young adults affords causal support for the hypothesis that the reduction over LIPFC during encoding produces the hallmarks of an age-related EM deficit: normal semantic retrieval at encoding, reduced subsequent episodic recognition accuracy, free recall, and the LPEM. Finally, we show that the reduced LPEM in young adults is associated with “additional” brain activity over similar brain areas as those activated when older adults show deficient retrieval. Hence, rather than supporting the compensation hypothesis, these data are more consistent with the scaffolding hypothesis, in which the recruitment of additional cognitive processes is an adaptive response across the life span in the face of momentary increases in task demand due to poorly-encoded episodic memories.

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