scholarly journals The effect of supplementation of Lactobacillus paracasei HII01 on salivary cortisol, and dehydroepiandrosterone sulfate (DHEA-S) levels

2020 ◽  
Vol 11 (1) ◽  
pp. 12-15
Author(s):  
Ekasit Lalitsuradej ◽  
Bhagavathi Sundaram Sivamaruthi ◽  
Sasithorn Sirilun ◽  
Phakkharawat Sittiprapaporn ◽  
Sartjin Peerajan ◽  
...  
Keyword(s):  
Hpa Axis ◽  
Cortisol Level ◽  
Salivary Cortisol ◽  
Dehydroepiandrosterone Sulfate ◽  
Chronic Fatigue ◽  
Lactobacillus Paracasei ◽  
Psychological State ◽  
Salivary Cortisol Level ◽  
Probiotic Intervention ◽  
Lactobacillus Paracasei Hii01

Background of the study: Fatigue is one of the serious health issues, and stress is the main factor that induces chronic fatigue syndrome (CFS). The dysregulation of stress management pathway may account for the development of CFS. The human body comprises several neurobiological networks to manage physical and emotional insults. Hypothalamic-pituitary- adrenal (HPA) axis is one of the important neuroendocrine networks involved in the neurophysiological activity of the host system. The response of HPA axis depends on the physical and psychological state of stress and other factors like time and duration of stress. The probiotic supplements are proved as an adjuvant therapeutic agent for several diseases.   Aims and Objective: The aim of the current study was to evaluate the effect of Lactobacillus paracasei HII01 supplementation on salivary cortisol and DHEA-S levels of fatigue subjects.   Materials and Methods: After 12-weeks of probiotic intervention significantly reduced the salivary cortisol level, while DHEA-S level was not affected. The ratio of cortisol: DHEA-S was reduced after probiotic intervention.   Results: The results concluded that L. paracasei HII01 has the ability to reduce the stress level in fatigue subjects by reducing the salivary cortisol level. Conclusion: The results evidently to recommend that the ingestion of 12.5 billion cells of L. paracasei HII01 per day for 12 weeks significantly amended HPA-Axis by lowering salivary cortisol and ratio cortisol: DHEA-S in fatigue subjects.

The cortisol awakening response in anxiety disorders and personality disorders and changes in salivary cortisol level after psychotherapy

2017 ◽  
Vol 41 (S1) ◽  
pp. S408-S408
Author(s):  
E. Dembinska ◽  
K. Rutkowski ◽  
J. Sobanski ◽  
K. Cyranka ◽  
M. Mielimaka ◽  
...  
Keyword(s):  
Anxiety Disorders ◽  
Personality Disorders ◽  
Hpa Axis ◽  
Cortisol Level ◽  
Salivary Cortisol ◽  
Primary Diagnosis ◽  
Post Treatment ◽  
Cortisol Awakening Response ◽  
Opposite Pattern ◽  
Salivary Cortisol Level

IntroductionThe hypothalamus—pituitary—adrenal axis (HPA axis) dysregulation plays an important role in the pathophysiology of anxiety disorders. Salivary cortisol level is a useful indicator of HPA axis dysfunction.ObjectivesMost data suggests elevated cortisol awakening response (CAR) in anxiety disorders, but there are studies indicating opposite pattern (flat CAR).AimGoal of this study was to determine whether patients with anxiety and personality disorders show a specific daily cortisol patterns and weather this pattern changes after 12 weeks of intensive predominantly psychodynamic combined group and individual psychotherapy.MethodThe studied population comprised 77 patients, mainly females (72.7%), with primary diagnosis of anxiety disorder 40.9% or personality disorder 59.1%. The Symptom Checklist “0” was used to assess the pre- and post-treatment levels of patients’ symptoms. Pre- and post-treatment cortisol levels were measured in three saliva samples collected during one day (at awakening, 30 min after awakening, at 22.00).ResultsThe obtained results were partly similar to previous research. We found four different daily CAR patterns: decreased (drop 30 min after awakening), flat (rise 0–49% 30 min after awakening), normal (rise 50–75% 30 min after awakening) and elevated (rise over 75% 30 min after awakening), two of them (flat and elevated) were considered as typical for anxiety disorders. Groups of CAR pattern differed significantly in the level of sleep symptoms, dysthymia symptoms and avoidance/dependency symptoms. The changes in the CAR pattern after psychotherapy were not significant.ConclusionsAnxiety disorders and personality disorders are characterized by more than two specific daily salivary cortisol patterns.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals A Prospective Observational Study on the Effects of Antidepressant Treatment on Hypothalamic-Pituitary-Adrenal Axis Regulation in Treatment-Resistant Depression

2021 ◽  
Author(s):  
. Kavita ◽  
Manoj Kumar Sahu ◽  
Pravin Gunderao Dhone ◽  
Ravi Kant Tiwari ◽  
Rajesh Hishikar
Keyword(s):  
Hpa Axis ◽  
Cortisol Level ◽  
Salivary Cortisol ◽  
Treatment Resistant Depression ◽  
Treatment Resistant ◽  
Hypothalamic Pituitary Adrenal ◽  
Significant Difference ◽  
Salivary Cortisol Level ◽  
Resistant Depression

Introduction: Dysregulation of Hypothalamic-Pituitary-Adrenal (HPA) axis can reduce the effects of antidepressants. Salivary cortisol level and Hamilton Depression Rating (HAM-D) score can be used to assess the level of improvement in the HPA axis and depressive disorders. Aim: To evaluate the changes in salivary cortisol level and HAM-D score in patients of Treatment Resistant Depression (TRD) and to investigate the association between them. Materials and Methods: The present prospective cohort study was conducted in the Department of Pharmacology and Psychiatry at Pt. JNM Medical College and Dr. BRAM Hospital Raipur (CG) over a period of one year, from June 2014 to June 2015. The participants were 52 diagnosed cases of TRD according to Diagnostic and Statistical Manual of Mental Disorders (DSM IV) criteria, who were taking antidepressant medications for at least four weeks. The salivary cortisol values and HAM-D scoring were done at baseline and follow-up at 8 weeks and 16 weeks and compared by student’s t-test and one-way ANOVA. Results: A significant difference (p<0.001) was noted in the mean salivary cortisol levels (1.15±0.31 and 0.72±0.24) mean HAM-D (29.67±1.43 and 16.26±7.08) scores at baseline and subsequent follow-up respectively. Conclusion: The therapeutic benefit of antidepressants could be due to alteration of HPA axis functioning.

scholarly journals Effect of one-month treatment with methylphenidate on salivary cortisol level of attention deficit hyperactivity disorder children

2021 ◽  
Vol 28 (1) ◽  
Author(s):  
Esraa Yahia Kholif ◽  
Salwa Mohamed Awad ◽  
Nasr Mohamed Attia ◽  
Ziyad Essam Tawhid ◽  
Mahmoud Elwasify
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Hpa Axis ◽  
Cortisol Level ◽  
Attention Deficit ◽  
Salivary Cortisol ◽  
Adhd Group ◽  
Healthy Children ◽  
Hyperactivity Disorder ◽  
Adhd Children ◽  
Salivary Cortisol Level

Abstract Background Attention deficit hyperactivity disorder (ADHD) is one of the most common neuropsychological disorders that affects children, adolescents, and adults. Dysfunction of the hypothalamic-pituitary-adrenal axis (HPA) has been implicated in its pathophysiology. So, this study aimed to compare the salivary cortisol level between ADHD children and healthy children. It also compared the salivary cortisol level of ADHD children before treatment and 1 month after treatment with methylphenidate. Results This study showed that there was a statistically significant decrease in salivary cortisol level of the ADHD group, specifically hyperactive/impulsive subtype compared to the control group. Furthermore, it showed a statistically significant increase of salivary cortisol level after treatment compared to before treatment in the ADHD group. Conclusions HPA axis dysfunction may be related to the pathophysiology of ADHD, specifically hyperactive/impulsive subtype. Methylphenidate positively affects the HPA axis of ADHD children.

Effects of Physical Workload on Salivary Cortisol Level

2004 ◽  
Vol 16 (1) ◽  
pp. 57 ◽  
Author(s):  
Dong Mug Kang ◽  
Byung Min Son ◽  
Sang Baek Koh ◽  
Junho Jang ◽  
Mia Son ◽  
...  
Keyword(s):  
Cortisol Level ◽  
Salivary Cortisol ◽  
Physical Workload ◽  
Salivary Cortisol Level

593 SALIVARY CORTISOL LEVEL IN PATIENTS WITH BURNING MOUTH SYNDROME

2009 ◽  
Vol 13 (S1) ◽  
Author(s):  
I. Glazar ◽  
H. Simic ◽  
I. Brekalo Prso ◽  
G. Brumini ◽  
S. Pezelj‐Ribaric
Keyword(s):  
Cortisol Level ◽  
Salivary Cortisol ◽  
Burning Mouth Syndrome ◽  
Salivary Cortisol Level ◽  
Burning Mouth

The effect of citrus ginger aroma on heart rate and salivary cortisol level during sleep at home

2018 ◽  
Vol 14 (4) ◽  
pp. 623-629
Author(s):  
Fang Jiang ◽  
Takemi Kobayashi ◽  
Takurou Ichihashi ◽  
Kanetoshi Ito ◽  
Shusaku Nomura
Keyword(s):  
Heart Rate ◽  
Cortisol Level ◽  
Salivary Cortisol ◽  
Salivary Cortisol Level ◽  
At Home

Impulsivity and Salivary Cortisol Level in Patients With Substance Dependence

2019 ◽  
Vol 18 (1) ◽  
pp. 1-9
Author(s):  
Hani H. Dessoki ◽  
Osama Refaat ◽  
Hisham Salah ◽  
Taghrid Tahoun ◽  
Maha Emadeldin ◽  
...  
Keyword(s):  
Cortisol Level ◽  
Salivary Cortisol ◽  
Substance Dependence ◽  
Salivary Cortisol Level

scholarly journals Morning Cortisol Levels and Perceived Stress in Irregular Shift Workers Compared with Regular Daytime Workers

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Harri Lindholm ◽  
Jari Ahlberg ◽  
Juha Sinisalo ◽  
Christer Hublin ◽  
Ari Hirvonen ◽  
...  
Keyword(s):  
Work Environment ◽  
Shift Work ◽  
Cortisol Level ◽  
Salivary Cortisol ◽  
Shift Workers ◽  
Long Run ◽  
Salivary Cortisol Level ◽  
Psychological Pressure ◽  
Media Work ◽  
Working Day

The 24/7 work environment and irregular shifts may markedly enhance the psychological pressure of media work. Changes in the hypothalamic-pituitary-adrenal axis reflect adaptation to stress. We analysed the correlation between subjective stress, sleep, salivary cortisol, and melatonin hormones among Finnish media workers with regular daytime work (RDW) and with irregular shift work (ISW) while controlling confounders. From 874 employees with regular daytime work or with irregular shift work, 70 employees from both groups were randomly selected. The final number of employees with a complete salivary cortisol profile was 66 in the RDW group and 65 in the ISW group. Five saliva samples were gathered from each subject before and during a working day. The salivary cortisol level of the sample taken 60 minutes after awakening (T1) was compared to the salivary cortisol level taken immediately after awakening (T0, T1/T0 ratio). The ratio was higher in the ISW group than in RDW group. Irregular shift work (P<0.001), severe stress (P<0.05), and less sleep (P<0.05) were independently associated with an augmented cortisol response after awakening. A stressful work environment and irregular shift work enhance cortisol excretion after waking. In the long run, this may become detrimental to health.

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