scholarly journals Glottic Squamous Cell Carcinoma Metastatic to the Brain

2013 ◽  
Vol 5 (1) ◽  
pp. 77-80
Author(s):  
Shashikant CU Patne ◽  
Satyajit Pradhan ◽  
Reena Mittal ◽  
Mohan Kumar ◽  
Pranay Tanwar

Spread of squamous cell carcinoma (SCC) commonly occurs vialocal lymphatic channels. Owing to scanty lymphatic drainage and vascular supply, SCC arising from the glottis rarely metastasizes. A 39-year-old male, operated for SCC of the glottis, presented 13 months later with complaints of headache. Computed tomography revealed a single ring-enhancing lesion in the right temporo-parietal region of the brain, suggestive of brain abscess. However, histopathological examination of the excised brain lesion showed metastasis of moderately differentiated SCC. Here, we report a rarecase of distant hematogenous brain metastasis of SCC of the glottis. DOI: http://dx.doi.org/10.3126/ajms.v5i1.5205 Asian Journal of Medical Science Vol.5(1) 2014 pp.77-80

2020 ◽  
Vol 2020 (10) ◽  
Author(s):  
Obed Rockson ◽  
Christine Kora ◽  
Abdelbassir Ramdani ◽  
Badr Serji ◽  
Tijani El Harroudi

Abstract Squamous cell carcinoma (SCC) of the colon is a rare malignant tumor occurring as either a primary or secondary lesion. Few cases of metastatic or secondary colonic SCC have been published. We report an unusual case of a 59-year-old female patient who was treated by Wertheim hysterectomy and adjuvant chemoradiation for stage IIB SCC of the uterine cervix. Two years later, she developed a metastatic location in the caecum causing an acute intestinal obstruction. She underwent an emergency open right hemicolectomy with ileocolic anastomosis and resection of two nodules of the umbilicus and the right parietal peritoneum. Histopathological examination confirmed a triple metastatic location of SCC. She is disease-free 11 months after surgery. We discuss the clinicopathological features, management strategies, and the prognosis of this rare entity.


2020 ◽  
Vol 17 (2) ◽  
pp. 55-59
Author(s):  
VIjay Kumar Gupta ◽  
Neeraj Basantani ◽  
A S Carvalho ◽  
Ekata Gupta ◽  
Nitesh Kumar Goyal

Head and neck squamous cell carcinoma metastasis to brain is unusual and rare. We present a case of a 61-year-old man with a primary oral  squamous cell carcinoma who was referred to our department for evaluation of decreased sensorium and hemiparesis. Magnetic resonance imaging of the brain revealed a ring enhancing central hypo-intense lesion with surrounding perilesional oedema on T1WI in the left frontal lobe. Left frontal craniotomy with gross total tumour removal was performed. Histopathological examination confirmed metastatic squamous cell carcinoma. The patient was subsequently offered adjuvant radiation therapy. To the best of our knowledge, few such cases have been reported.


2020 ◽  
Vol 25 (1) ◽  
pp. 46-49
Author(s):  
Ji-An Choi ◽  
Jung-Ha Kwak ◽  
Jeong-Hwan Choi ◽  
Kwang-Ryeol Lim ◽  
Dae Cheol Kim ◽  
...  

Malignant tumors of the hand are rare. Squamous cell carcinoma (SCC) is the most common tumor that can develop at the nail bed. However, its prevalence is extremely rare. We report a male patient with SCC in the middle finger and provide a review of related literature. A 70-year-old male patient presented with subungal exudate of the right middle finger for 2 years. The lesion was treated by the patient himself without any relief. He visited the other hospital and underwent removal of the affected fingernail followed by histopathological examination. An extended excision was performed to remove the lesion located in close proximity with the distal phalanx along with a portion of the phalangeal soft tissues. The tumor shows malignant squamous sheets and nests with invasive growth pattern and pleomorphism. At the 6-month postoperative follow-up, neither symptom relapse nor other complications were observed. Various types of skin cancers, such as SCCs and malignant melanomas, can develop in the hand. However, their incidence is extremely rare. In particular, subungal lesions, which may be mistaken as fungal nail infections, require histopathological examination if they respond only slowly to treatment.


2020 ◽  
Vol 26 (2) ◽  
pp. 16
Author(s):  
K.P. Karthik ◽  
R. Balamurugan ◽  
T. Sahana Pushpa

Introduction: Oral papillary squamous cell carcinoma (OPSCC) is a rare variant of squamous cell carcinoma with an unusual presentation in the palate. Observation: This case report presents a 68 year old male who reported with pain in the roof of the jaw for the past one month. The patient gave a history of a small ulcer over the right palatal region since a year which gradually increased in size. History also revealed that he was a tobacco chewer for around five years and had quit the habit one year back. Clinically, a proliferative growth in the right palatal region was apparent. The growth was firm in consistency and had well-defined borders that crossed the midline of palate. Based on the noticeable clinical signs, the case was provisionally diagnosed as verrucous carcinoma. Histopathology report of the incisional biopsy confirmed the case to be non-invasive oral papillary squamous cell carcinoma. Commentary: OPSCC displays either a papillary variant or exophytic pattern. It has a better prognosis than squamous cell carcinoma of similar clinical stage but is worse than verrucous carcinoma. Conclusion: Since OPSCC may mimic other benign conditions of oral cavity, evaluation of clinical parameters that are associated with the risk of carcinoma is mandatory. This article highlights the significance of histopathological examination that aids the clinician to arrive at a diagnosis for any suspicious papillary lesions.


2021 ◽  
Vol 7 ◽  
pp. 2513826X2110084
Author(s):  
Weston Thomas ◽  
Kevin Rezzadeh ◽  
Kristie Rossi ◽  
Ajul Shah

Introduction: Skin graft reconstruction is a common method of providing wound coverage. Rarely, skin grafting can be associated with the development of squamous cell carcinoma (SCC) in the graft donor site. Case Report: The patient is a 72-year old male with a 15-year history of bilateral hip wounds. He underwent a multitude of treatments previously with failed reconstructive efforts. After presenting to us, he underwent multiple debridements and eventual skin grafting. Within 4 weeks of the final skin graft, a mass developed at the skin graft donor site at the right thigh. Excisional biopsy returned a well differentiated keratinizing SCC. Discussion/Conclusion: This case demonstrates the acute presentation of SCC in a patient following a skin graft without known risk factors. The purpose of this unique case report is to highlight a very rare occurrence of SCC at a skin graft donor site.


2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Tapan Kumar Sahoo ◽  
Saroj Kumar Das ◽  
Chandraprava Mishra ◽  
Ipsita Dhal ◽  
Rohani Nayak ◽  
...  

Primary squamous cell carcinoma of the renal parenchyma is an extremely rare entity. The diagnosis of squamous cell carcinoma of the renal pelvis is usually unsuspected due to the rarity and inconclusive clinical and radiological features. Most of the patients are diagnosed at an advanced stage and are with poor outcome. Radical nephrectomy is the mainstay of the treatment. We reported a case of squamous cell carcinoma of the kidney in a 50-year-old female who presented with the right sided abdomen pain. The patient was treated with radical nephrectomy.


2002 ◽  
Vol 29 (1) ◽  
pp. 47-54 ◽  
Author(s):  
Hamid R Djalilian ◽  
Muhammet Tekin ◽  
Walter A Hall ◽  
George L Adams

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Monet E. Meter ◽  
David J. Nye ◽  
Christian R. Galvez

Introduction. It is rare for actinic or squamous cell carcinoma (SCC) in situ to metastasize. Case Presentation. A 67-year-old male had a significant medical history including severe psoriatic arthritis treated with UVB, methotrexate, and rapamycin. He had twenty-five different skin excisions of actinic keratosis four of which were invasive SCC. Our patient developed shortness of breath necessitating a visit to the emergency department. A CT scan of his chest revealed a mass in the right lower lung. A subsequent biopsy of the mass revealed well-differentiated SCC. He underwent thoracoscopic surgery with wedge resection of the lung lesion. Discussion. Actinic keratosis (AK) is considered precancerous and associated with UV exposure. It exists as a continuum of progression with low potential for malignancy. The majority of invasive SCCs are associated with malignant progression of AK, but only 5–10% of AKs will progress to malignant potential. Conclusion. In this case, a new finding of lung SCC in the setting of multiple invasive actinic cutaneous SCC associated with a history of extensive UV light exposure and immunosuppression supports a metastatic explanation for lung cancer.


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