scholarly journals Oral papillary squamous cell carcinoma (OPSCC): a rare presentation in the palate

2020 ◽  
Vol 26 (2) ◽  
pp. 16
Author(s):  
K.P. Karthik ◽  
R. Balamurugan ◽  
T. Sahana Pushpa
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Histopathological Examination ◽  
Verrucous Carcinoma ◽  
Clinical Stage ◽  
Clinical Signs ◽  
Rare Presentation ◽  
Papillary Squamous Cell Carcinoma ◽  
The Right

Introduction: Oral papillary squamous cell carcinoma (OPSCC) is a rare variant of squamous cell carcinoma with an unusual presentation in the palate. Observation: This case report presents a 68 year old male who reported with pain in the roof of the jaw for the past one month. The patient gave a history of a small ulcer over the right palatal region since a year which gradually increased in size. History also revealed that he was a tobacco chewer for around five years and had quit the habit one year back. Clinically, a proliferative growth in the right palatal region was apparent. The growth was firm in consistency and had well-defined borders that crossed the midline of palate. Based on the noticeable clinical signs, the case was provisionally diagnosed as verrucous carcinoma. Histopathology report of the incisional biopsy confirmed the case to be non-invasive oral papillary squamous cell carcinoma. Commentary: OPSCC displays either a papillary variant or exophytic pattern. It has a better prognosis than squamous cell carcinoma of similar clinical stage but is worse than verrucous carcinoma. Conclusion: Since OPSCC may mimic other benign conditions of oral cavity, evaluation of clinical parameters that are associated with the risk of carcinoma is mandatory. This article highlights the significance of histopathological examination that aids the clinician to arrive at a diagnosis for any suspicious papillary lesions.

scholarly journals Carcinoma of Vagina in Utero-Vaginal Prolapse: A Rare Presentation

2012 ◽  
Vol 52 (186) ◽  
Author(s):  
S Acharya ◽  
DK Uprety
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Histopathological Examination ◽  
Large Cell ◽  
Uterovaginal Prolapse ◽  
Rare Entity ◽  
Rare Presentation ◽  
Vaginal Carcinoma ◽  
Keywords Squamous Cell Carcinoma

Primary vaginal carcinoma in uterovaginal prolapse is a rare entity. We report a case of an 84-years-old lady, who presented with long standing vaginal ulcer in association with third degree uterovaginal prolapse. Incisional biopsy was taken from the ulcer. Histopathological examination showed a large cell keratinizing squamous cell carcinoma. Keywords: Squamous cell carcinoma, uterovaginal prolapse, vaginal carcinoma.

scholarly journals A case report of an unusual caecal metastatic location of a primary cervical squamous cell carcinoma

2020 ◽  
Vol 2020 (10) ◽  
Author(s):  
Obed Rockson ◽  
Christine Kora ◽  
Abdelbassir Ramdani ◽  
Badr Serji ◽  
Tijani El Harroudi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Histopathological Examination ◽  
Management Strategies ◽  
Cervical Squamous Cell Carcinoma ◽  
Right Hemicolectomy ◽  
Secondary Lesion ◽  
The Right ◽  
Metastatic Location

Abstract Squamous cell carcinoma (SCC) of the colon is a rare malignant tumor occurring as either a primary or secondary lesion. Few cases of metastatic or secondary colonic SCC have been published. We report an unusual case of a 59-year-old female patient who was treated by Wertheim hysterectomy and adjuvant chemoradiation for stage IIB SCC of the uterine cervix. Two years later, she developed a metastatic location in the caecum causing an acute intestinal obstruction. She underwent an emergency open right hemicolectomy with ileocolic anastomosis and resection of two nodules of the umbilicus and the right parietal peritoneum. Histopathological examination confirmed a triple metastatic location of SCC. She is disease-free 11 months after surgery. We discuss the clinicopathological features, management strategies, and the prognosis of this rare entity.

scholarly journals Bilateral Breast Lumps as a Presentation of Disseminated Squamous Cell Carcinoma of Lung

2014 ◽  
Vol 7 ◽  
pp. CCRep.S13832
Author(s):  
Pramila Dharmshaktu ◽  
Ankur Jain ◽  
Naresh Gupta ◽  
Abhilasha Garg ◽  
Seema Kaushal
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lower Lobe ◽  
Malignant Cells ◽  
Rare Presentation ◽  
Ct Guided ◽  
The Past ◽  
Breast Lumps ◽  
The Right

We present the case of a 65-year-old female who presented to our hospital with nodular swelling in her breast that first appeared in the right upper quadrant 10 months earlier, followed by involvement of the left upper quadrant along with nodular swelling in the right inguinal region for the past six months. She was also complaining of breathlessness on exertion and right-sided pleuritic chest pain for the past one year. Her chest X-ray showed well defined consolidation in the right lower lobe of the lung with pleural effusion. Further pleural tap showed malignant cells with squamous differentiation. Fine needle aspiration cytology (FNAC) from breast lumps was suggestive of malignant cells with morphology of cells likely to be squamous. CT-guided biopsy of the lung mass showed moderately differentiated squamous cell carcinoma of the lung. She succumbed to her illness following severe respiratory distress. Breast lump secondary to lung malignancy is very rare. Squamous cell carcinoma presenting as breast metastasis is a very rare presentation and reported in few cases. No previous case reporting bilateral breast lumps as a presentation of squamous cell carcinoma of the lung could be found in the literature.

scholarly journals Rare presentation of gingival squamous cell carcinoma of maxillary posterior region mimicking pyogenic granuloma in a non-smoker – A case report

2021 ◽  
Vol 6 (3) ◽  
pp. 174-178
Author(s):  
R. Reshmaa ◽  
R. Kadhiresan ◽  
U. Arunmozhi ◽  
R. Shanmugapriya
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Histopathological Examination ◽  
Malignant Neoplasm ◽  
Pyogenic Granuloma ◽  
Oral Carcinoma ◽  
Rare Presentation ◽  
Gingival Squamous Cell Carcinoma

Gingival Squamous cell carcinoma (GSCC) in maxilla is a rare malignant neoplasm especially when compared with mandible. The most common sites of oral carcinoma are being the lateral border of the tongue and the floor of the mouth which is followed by palate, buccal mucosa and rarely in gingiva. The clinical picture of oral carcinoma can be misguided for gingival overgrowth, desquamative lesions, traumatic ulcers or even pyogenic granuloma. Maxillary oral gingival carcinoma is a rare entity especially in a non-smoker. In this case report, a 70-year-old male patient presented with a gingival lesion in maxilla 24,25 region mimicking pyogenic granuloma without having a tobacco history. A thorough clinical, radiographical and histopathological examination was done and led to the diagnosis of GSCC and the treatment was initiated.Creating awareness among practitioners about gingival squamous cell carcinoma mimicking pyogenic granuloma in dental practice.

Papillary Squamous Cell Carcinoma of the Cervix: Human Papillomavirus (HPV) Status and Clinicopathologic Features

2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S24-S24
Author(s):  
S A Schechter ◽  
A Elshaikh ◽  
H Walline ◽  
S L Skala
Keyword(s):  
Squamous Cell Carcinoma ◽  
Human Papillomavirus ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Clinical Stage ◽  
Hpv Infection ◽  
Low Grade ◽  
Cervical Neoplasm ◽  
Hpv Status ◽  
Papillary Squamous Cell Carcinoma

Abstract Introduction/Objective Papillary squamous cell carcinoma (PSCC) is a rare cervical neoplasm composed of papillae lined by atypical squamous/transitional cells without koilocytosis. It is unclear whether PSCC is related to human papillomavirus (HPV) infection, though rare cases were reportedly associated with HPV type 16. PSCC is thought to be more common in postmenopausal women. Some authors have suggested that PSCC may be understaged due to the prominent exophytic nature of the superficial aspect and relatively deep location of underlying infiltrative nests. It has also been suggested that PSCC has a tendency to recur and/or metastasize late. Methods The surgical pathology database of a single large academic institution was searched for squamous cell carcinoma (or squamous cell carcinoma in situ) with papillary features from the cervix, sampled between 1996 and 2018. PCR for human papillomavirus (HPV) L1 protein was run, with sequencing of positive samples. Results 5 cases diagnosed as “papillary squamous cell carcinoma” were identified. Patient age ranged from 21–63 years (mean 46 years). All tumors showed papillary architecture, often with complex branching and/or fusion. The neoplastic cells had a squamous/transitional appearance with moderate to marked cytologic atypia and at most focal keratinization. Stage ranged from pT1b1 to pT3b (clinical stage IB1 to IVB). HPV L1 PCR was positive in only one case; sequencing confirmed HPV type 16. Upon closer review, the HPV-positive case was from the youngest patient and showed adjacent low-grade squamous intraepithelial lesion (LSIL) as well as focal koilocytic change within the papillary tumor. Conclusion Our findings suggest that even in patients with HPV infection, PSCC may be an HPV-independent malignancy. In multiple cases, it was difficult to obtain definitive histologic evidence of invasion prior to resection.

scholarly journals Rare squamous cell carcinoma of the kidney with concurrent xanthogranulomatous pyelonephritis: A case report and review of the literature

Open Medicine ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. 128-133
Author(s):  
Tsung-Hsin Chang ◽  
Jen-Shu Tseng
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Radical Nephrectomy ◽  
Medical Literature ◽  
Xanthogranulomatous Pyelonephritis ◽  
Rare Presentation ◽  
English Medical Literature ◽  
History Of ◽  
The Right

Abstract Case presentation In the current study, we report a 69-year-old female patient who was initially diagnosed with xanthogranulomatous pyelonephritis (XGPN) with nephrolithiasis and a peri-renal abscess. She presented to our department with right flank pain. Physical examination revealed right costovertebral angle knocking pain and computed tomography revealed dilated calyces and one staghorn stone over right kidney, with multiple abscess accumulations over the right peri-renal region. Right radical nephrectomy was performed using a transperitoneal flank approach, and pathology revealed squamous cell carcinoma (SCC) with concurrent XGPN. The patient was alive at 4 months post-operative follow-up. To the best of our knowledge, this is only the fifth case of renal SCC with concurrent XGPN reported in the English medical literature. Conclusion Renal SCC with coexisting XGPN is an extremely rare presentation and only four cases have been previously reported in the English medical literature. A positive diagnosis for this rare combination of diseases was established, based on pathological and immunohistochemical examinations after radical nephrectomy. Poor prognosis has been reported in such cases. Malignancies should be considered in patients with a long-standing history of urolithiasis.

scholarly journals Glottic Squamous Cell Carcinoma Metastatic to the Brain

2013 ◽  
Vol 5 (1) ◽  
pp. 77-80
Author(s):  
Shashikant CU Patne ◽  
Satyajit Pradhan ◽  
Reena Mittal ◽  
Mohan Kumar ◽  
Pranay Tanwar
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Histopathological Examination ◽  
Medical Science ◽  
Brain Lesion ◽  
Lymphatic Drainage ◽  
Vascular Supply ◽  
The Right ◽  
The Brain

Spread of squamous cell carcinoma (SCC) commonly occurs vialocal lymphatic channels. Owing to scanty lymphatic drainage and vascular supply, SCC arising from the glottis rarely metastasizes. A 39-year-old male, operated for SCC of the glottis, presented 13 months later with complaints of headache. Computed tomography revealed a single ring-enhancing lesion in the right temporo-parietal region of the brain, suggestive of brain abscess. However, histopathological examination of the excised brain lesion showed metastasis of moderately differentiated SCC. Here, we report a rarecase of distant hematogenous brain metastasis of SCC of the glottis. DOI: http://dx.doi.org/10.3126/ajms.v5i1.5205 Asian Journal of Medical Science Vol.5(1) 2014 pp.77-80

scholarly journals ORAL CAVITY SQUAMOUS CELL CARCINOMA IN A CASE OF IFAP SYNDROME WITH CHRONIC MYELOID LEUKEMIA ON LONG TERM HYDROXYUREA: A RARE PRESENTATION

2017 ◽  
Vol 10 (5) ◽  
pp. 1 ◽  
Author(s):  
Anshul Singh ◽  
Uday Kumar P ◽  
S Anusha Reddy ◽  
Prahlad H Yathiraj ◽  
Mamidipudi S Vidyasagar
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Histopathological Examination ◽  
Blast Crisis ◽  
Palliative Radiotherapy ◽  
Rare Presentation ◽  
Proliferative Growth ◽  
Erosive Lichen Planus

We report a case of  a patient  in his early  30s’ who presented with an ulcero-proliferative growth over the left buccal mucosa , he was also on treatment for CML in blast crisis on Hydroxyurea and a known case of Ichthyosis Follicularis, Alopecia, and Photophobia (IFAP) syndrome. Though a working diagnosis of chloroma / Hydroxyurea induced erosive Lichen planus  was suspected, the histopathological examination of the lesion was suggestive of Squamous cell Carcinoma. He was subsequently planned for palliative radiotherapy . 

scholarly journals Oral carcinoma cuniculatum: an unacquainted entity with diagnostic challenges—a case report

2022 ◽  
Vol 34 (1) ◽  
Author(s):  
Safaa Baz ◽  
Hatem Wael Amer ◽  
Ali A. Wahed
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Verrucous Carcinoma ◽  
Oral Carcinoma ◽  
Diagnostic Features ◽  
Papillary Squamous Cell Carcinoma ◽  
Well Differentiated ◽  
Carcinoma Cuniculatum

Abstract Background Oral carcinoma cuniculatum (OCC) is an unacquainted well-differentiated subtype of oral squamous cell carcinoma, which displays unique clinic-pathological features. Up to date, OCC remains rare with about 75 reported cases, and is frequently missed or even misdiagnosed. Case presentation The aim of the present work was: to report a case of OCC in mandibular gingiva and to highlight its main clinic-pathological diagnostic features: with an exophytic cobble-stone surface and a characteristic endophytic burrowing architecture, as well as to differentiate between it and other closely similar lesions including verrucous carcinoma, papillary squamous cell carcinoma, and well-differentiated conventional oral squamous cell carcinoma. Conclusions An accurate diagnosis of OCC entails awareness of the clinicians and pathologists about its entity, proper knowledge of the diagnostic clinical and histopathological evidence, and the ability to differentiate it from closely similar lesions.

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