scholarly journals Incidence of Post Operative Wound Infection Following the Use of Antibiotics in Clean Contaminated Head and Neck Surgery in a Tertiary Care Centre in Eastern Nepal

2017 ◽  
Vol 1 (1) ◽  
pp. 51-55 ◽  
Author(s):  
K. Chapagain ◽  
R. Pokharel ◽  
R. Acharya ◽  
S. Shah ◽  
B.D. Paranjape

Introduction Post operative wound infection continues to be the major concern even after the appropriate antibiotic coverage.Objective To find out the incidence of post operative wound infection following the use of antibiotics in clean contaminated head and neck surgery in a tertiary care centre in Eastern Nepal.Methodology It is a prospective study conducted at Department of Otorhinolaryngology and Head and Neck Surgery, Nobel Medical  College Teaching Hospital, Biratnagar from 14th April 2013 to 12th April 2015. Patient who underwent clean contaminated head and neck surgery were followed up on 1st, 3rd and 6th post–operative day (POD) and wounds were inspected for any signs of wound infection.Results A total of 144 patients undergoing various clean contaminated head and neck surgeries were included in this study. Tonsillectomy was the commonest surgery performed (40.27%). An overall wound infection rate was 11.80%. Serous discharge rd from the surgical site observed on 3rd post operative day was the most common presentation of wound infection (29.41%). Parotidectomy was the surgery presenting with highest rate of wound infection (31.25%).Conclusion This study concludes that even the best technique and appropriate antibiotic has not completely eliminated the problem of wound infection in clean contaminated head and neck surgery.Birat Journal of Health Sciences 2016 1(1): 51-55

1997 ◽  
Vol 76 (11) ◽  
pp. 790-798 ◽  
Author(s):  
Randal S. Weber

Perioperative antibiotic treatment significantly reduces the risk of postoperative wound infection and is cost-effective in clean-contaminated head and neck operations. A clear consensus on the most suitable single agent or combination is, however, lacking. Most surgical wound infections involve both gram-positive and gram-negative aerobes and anaerobes; some organisms may exhibit antibiotic resistance through beta-lactamase production. Comparative trials have indicated that combinations with both aerobic and anaerobic activity provide protection superior to that achieved with single agents active against only aerobic pathogens. Recent results suggest that the beta-lactam/beta-lactamase-inhibitor combination ampi-cillin/sulbactam is cost-effective for perioperative treatment of patients undergoing head and neck surgery.


2018 ◽  
Vol 5 (2) ◽  
pp. 8-10
Author(s):  
Kumud Chapagain ◽  
Rais Pokharel ◽  
Kumud Kumar Kafle ◽  
Bimal Kumar Sinha

Objective: To compare the efficacy of amoxicillin and ciprofloxacin used in clean contaminated ear surgery during the early post operative period.Materials and Methods: It is a longitudinal, prospective study conducted at Department of Otorhinolaryngology and Head and Neck Surgery, TUTH from 1st April 2011 to 30th December 2011.  Patient who underwent clean contaminated ear surgery were followed up on 1st, 3rd and 7th post – operative day (POD) and wounds were inspected for any signs of wound infection.Results: 103 patients who under went various clean contaminated ear surgeries were included in this study. Maximum patients were aged 14-29 years. Ciprofloxacin was prescribed to 80 (77.7%) patients and amoxicillin to 23 (20.3%) patients. Overall wound infection was present on 6.2% (5/80) patients receiving ciprofloxacin and on 4.34% (1/23) patients receiving amoxicillin. The  most common procedure performed was MRM (53%). Wound infection was present in 9% (4/44) of patients undergoing MRM under coverage of ciprofloxacin and on 9% (1/11) patients under coverage of amoxicillin.Conclusion: Though the rate of wound infection was more in patient using ciprofloxacin than amoxicillin but it was not statically significant.Nepalese Journal of ENT Head and Neck Surgery, Vol. 5, No. 2, 2014, page: 8-10


2015 ◽  
Vol 53 (10) ◽  
pp. e66
Author(s):  
A. Rennie ◽  
A. Yuffa ◽  
N. Galligan ◽  
P. Praveen ◽  
T. Martin ◽  
...  

2017 ◽  
Vol 157 (4) ◽  
pp. 580-588 ◽  
Author(s):  
Peter M. Vila ◽  
Joseph Zenga ◽  
Susan Fowler ◽  
Ryan S. Jackson

Objective To determine the optimal duration and type of antibiotic prophylaxis in patients undergoing clean-contaminated resection for head and neck cancer. Data Sources Search strategies were created by a medical librarian, implemented in multiple databases, and completed in June 2016. Review Methods The population of interest was adults ≥18 years undergoing clean-contaminated head and neck surgery, intervention was postoperative antibiotic prophylaxis, comparator was duration and types of antibiotics used, outcome was the wound infection rate, and the study design was randomized controlled trials (RCTs). Studies were excluded if not randomized, did not use systemic antibiotics, did not study wound infections, or included children. After excluding duplicates, the search strategy yielded 427 abstracts. After applying inclusion and exclusion criteria, 67 studies were screened, leaving 19 RCTs for review. PRISMA guidelines were followed. A random-effects model was used for meta-analysis. Results Meta-analysis of 340 patients in 4 RCTs showed that the pooled relative risk of wound infection was 0.98 (95% confidence interval [CI], 0.58-1.61; P = .718; I2 = 0.0%) in patients receiving 1 day vs 5 days of prophylaxis. Conclusion This study provides evidence that there is no difference in the risk of wound infection with 1 day vs 5 days of systemic antibiotic prophylaxis in clean-contaminated head and neck surgery, consistent with existing guidelines. Future large randomized trials are needed to more clearly define the appropriate choice of prophylaxis in penicillin-allergic patients.


2018 ◽  
Vol 6 (2) ◽  
pp. 42-44
Author(s):  
B Sharma ◽  
A Devkota ◽  
SC Pant

Introduction: Study on prevalence of psychiatric disorders in Palpa and nearby districts which lie in western Nepal, is not much studied till date. We therefore conducted this study aiming to see the pattern of psychiatric illness in an Outpatient Department of Lumbini Medical College which is a tertiary care centre located in Palpa district.Material And Method: : This is a retrospective study where outpatient record of all new cases attending the Psychiatry OPD from 29th Oct 2014 to 29th Dec 2014 were studied and statistical analysis were done. The number of new patients were 107.Results: Out of 107 patients, 60.74 % (65)) were females and 39.26 %( 42) were males. Patients of age group 31-40yrs showed the largest proportion (27.49%) followed by age group 41-50yrs (24.29%). Majority cases were illiterate (69.15%) followed by primary level of education (14.95%). The occupation of most of the cases were household work (35.51%) followed by farming (31.77%). Anxiety disorder (27.10%) was the most frequent diagnosis ahead of “Others” (18.69%) followed by depressive disorder (15.88%).Conclusion: Most of the new patients attending the psychiatry OPD of Lumbini Medical College were females, of 31-40 age group and most of the patients suffered from anxiety disorders. J Psychiatrists’ Association of Nepal Vol. 6, No. 2, 2017, Page: 42-44


1994 ◽  
Vol 108 (11) ◽  
pp. 973-979 ◽  
Author(s):  
Miriam I. Redleaf ◽  
Carol A. Bauer

AbstractA multivariant analysis of the value of the use of a pre-operative topical antiseptic mouthwash to reduce the incidence of post-operative wound complications in 106 consecutive patients undergoing head and neck surgery involving the oral cavity or oropharynx was carried out at the University of Iowa, Department of Otolaryngology-Head and Neck Surgery. An oral presentation employing povidone–iodine solution was used for 43 patients. The remaining 63 patients studied received no oral presentation. Unfavourable wound outcome was not associated with age, sex, presence and condition of teeth, or serious pre-existing medical illnesses. A significant correlation was found between post-operative wound breakdown and type of closure, stage of disease, and previous operation or radiotherapy. The use of an oral preparation correlated significantly with favourable wound outcome independent of all other variables (p<0.01).Our data support the use of a topical antiseptic mouthwash to reduce the incidence of post-operative wound complications in surgery of the oral cavity and oropharynx.


Author(s):  
Umesh Bahadur Singh ◽  
Dileep Garg ◽  
Manoj Kumar Joshi ◽  
Vinay Mathur ◽  
Jitendra Grover

Introduction: Paediatric perineal trauma or Anogenital Injury (AGI) in the paediatric age group remains lesser reported in under-developed areas or rural areas of India. Most of these injuries remain under reported to tertiary care centres because of a social stigma or poor access to a health facility. Aim: To present the clinico-epidemiological parameters of AGI in children and to assess the outcome of staged and definitive management in these children, comparing the results with other similar studies. Materials and Methods: This was a retrospective study on data of 11 cases (age range 1-14 years, seven cases were boys and 4 cases were girls) of paediatric anogenital injuries, admitted at the tertiary care centre from 1st July 2018 to 30th June 2020 were analysed. Data of all the patients, demographic details, relevant clinical history such as time of presentation, mode of injury and type of management, outcomes and complications was collected and studied. All the collected data was analysed by calculating mean±SD, frequency (n) and percentages (%). Results: Road traffic accident was the most common cause of AGI (n=5, 45.5%), followed by sexual assault (n=3, 27.3%). Wound infection in late presenters (n=5, 45.5%) was the most common complication affecting the outcome. Children with a primary diversion of the faecal stream or diversion colostomy (n=5, 45.5%) as an associated procedure had a better outcome. Primary repair without diversion (n=3, 27.3%) was noticed to have a high incidence of wound infection and anovaginal scaring. Conclusion: A high incidence of poor wound healing related to late presentation and malnutrition noted among these AGI cases belonging to rural or semi-urban settings. Management of these injuries, therefore, needs to be individualised on case-to-case basis. The diversion stoma formation seems to be considered in all high grade anogenital injuries and selected lower grade injuries with evidence of secondary infection or poor healing of the primary repair.


2018 ◽  
Vol 4 (8) ◽  
pp. 592-596
Author(s):  
Dr. Bhumi Padia ◽  
◽  
Dr. Mukund Dhokiya ◽  

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