scholarly journals Levels of T4 and TSH in mother's blood and in cord blood at the time of delivery

2013 ◽  
Vol 11 (1) ◽  
pp. 6-10
Author(s):  
K Agrawal ◽  
BH Paudel ◽  
PN Singh ◽  
S Majhi ◽  
H Pokhrel ◽  
...  

Background: In conditions of maternal iodine deficiency, the frequency distribution of neonatal thyroid stimulating hormone (TSH) is shifted towards elevated values. Elevated serum TSH in the neonates indicates insufficient supply of thyroid hormones to the neonates, a major complication of iodine deficiency. Objectives: To determine the cord blood serum T4 and TSH levels and interrelationships with maternal thyroid hormones. Method: cord blood serum T4 and TSH levels of 45 consecutive newborns born at BPKIHS, Dharan, Nepal and maternal T4 and TSH levels were analyzed using ELISA based kits. Results: The mean age of mothers was 23.73± 3.86 years and average weight of the neonates was 3.038±0.45 Kg. The median levels of maternal and neonatal T4 were 1.09 ng/dl and 1.26 ng/ dl respectively. The corresponding median TSH levels were 3.71 mIU/L and 11.9 mIU/L. The maternal and neonatal levels of T4 were positively correlated. In 36 mothers who had TSH level within euthyroid range (0.3-6.2 mIU/L, Thyroid lab of BPKIHS), 22 neonates (61.11%) had TSH levels above 10 mIU/L. Among 9 mothers having TSH levels above 6.2 mIU/L, 7 (77.77%) neonates had TSH levels above 10 mIU/L. Conclusion: Overall 29 (64.44%) neonates had TSH level above 10 mIU/L which indicates mild degree of iodine deficiency. Iodine supplementation is required before pregnancy in majority of women of reproductive age. Health Renaissance, January-April 2013; Vol. 11 No.1; 6-10 DOI: http://dx.doi.org/10.3126/hren.v11i1.7593

Pathobiology ◽  
2006 ◽  
Vol 73 (6) ◽  
pp. 310-316 ◽  
Author(s):  
Zofia Galewska ◽  
Lech Romanowicz ◽  
Tomasz Gogiel ◽  
Stefan Jaworski ◽  
Edward Bańkowski

2001 ◽  
Vol 124 (2) ◽  
pp. 190-196 ◽  
Author(s):  
M. S. Ronkainen ◽  
A. -M. Hämäläinen ◽  
P. Koskela ◽  
H. K. Åkerblom ◽  
M. Knip ◽  
...  

2017 ◽  
Vol 27 (2) ◽  
pp. 133-142
Author(s):  
Gennadiy A. Kovalov ◽  
◽  
Iryna O. Ischenko ◽  
Olga V. Naumova ◽  
Ninel V. Dedukh ◽  
...  

2021 ◽  
pp. 101-109
Author(s):  
Irina Bondarenko ◽  
Andrey Lazorenko ◽  
Oksana Shkromada

The results of the study of the effect of cord blood serum and “Actovegin” (Takeda, Ukraine) on the reproductive function of cows in a comparative aspect are presented. The aim of the study was to analyze the effect of cord blood serum and Actovegin on the reproductive function of uterine cows in a comparative aspect. Materials and methods. The research was conducted during 2017-2020 in four dairy farms of Sumy region with tethered and untied maintenance. In 128 cows of different breeds and productivity, the timing of sexual cycling was studied and analyzed in comparison with the spontaneous sexual cycle with the use of cord blood serum and the drug "Actovegin" (Takeda, Ukraine). Results. It was found that in cows with tethered content, the number of days from the introduction of 15 ml of cord blood serum to the manifestation of the excitation stage was significantly less compared to the spontaneous manifestation of sexual desire (5.63±0.36 and 14.38±2.1, respectively). When cows with loose content were administered 10 ml of cord blood serum in combination with the drug "Actovegin", the number of days before the manifestation of sexual cycling was lower by 18.3 % compared with the rate of spontaneous sexual desire (4.31±0.38 and 18.25±1.89, respectively). Conclusions. As a result of using 10 ml of cord blood serum in combination with the drug "Actovegin", in cows of different productivity and under different housing conditions, the number of days before the onset of the stage of arousal is significantly reduced compared to the spontaneous manifestation of sexual desire. Cows of different productivity and with different housing conditions come to the sexual desire significantly faster with the use of 15 ml of cord blood serum compared to the spontaneous manifestation of sexual desire.


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