scholarly journals Clinical profile of end stage renal disease in patients on maintenance haemodialysis in a tertiary hospital

2020 ◽  
Vol 13 (2) ◽  
pp. 169-172
Author(s):  
Durga Dhungana ◽  
Chandra Bahadur Pun ◽  
Bidhya Banstola

Introduction and Objectives: Chronic kidney disease is an increasing health problem worldwide and the burden of such patients is increasing in developing countries like Nepal as well. The final treatment for End Stage Renal Disease is only renal replacement therapy. The objective was to study the demographic and clinical profile of patients with End Stage Renal Disease undergoing haemodialysis. Methods: This was a prospective, observational study carried out in a tertiary hospital after obtaining ethical consent from the Institutional Review Board. The study period was from June 1st to August 31st, 2019. Thirty seven patients, older than 15 years who were on maintenance haemodialysis on regular basis in the hospital for at least 3 months were selected for the study. Patient’s records were used for the data collection as well as direct questionnaire to the patients on follow up for routine haemodialysis. Data were entered into Statistical Package for the Social Sciences 21 and descriptive analysis was done. Results: Twenty-six patients were under 50 years with male: female ratio of 1.64:1. Mean duration of haemodialysis of patients was 3.82 years. Most common cause for end stage renal disease was hypertension followed by idiopathic cause. Anaemia and hypocalcaemia were found to be the common complications associated with the patients. Conclusions: Prevention and early treatment may be the key to decrease the incidence of chronic kidney disease patients and also halt the progression to End stage renal disease.  

Author(s):  
Chih-Chien Chiu ◽  
Ya-Chieh Chang ◽  
Ren-Yeong Huang ◽  
Jenq-Shyong Chan ◽  
Chi-Hsiang Chung ◽  
...  

Objectives Dental problems occur widely in patients with chronic kidney disease (CKD) and may increase comorbidities. Root canal therapy (RCT) is a common procedure for advanced decayed caries with pulp inflammation and root canals. However, end-stage renal disease (ESRD) patients are considered to have a higher risk of potentially life-threatening infections after treatment and might fail to receive satisfactory dental care such as RCT. We investigated whether appropriate intervention for dental problems had a potential impact among dialysis patients. Design Men and women who began maintenance dialysis (hemodialysis or peritoneal dialysis) between January 1, 2000, and December 31, 2015, in Taiwan (total 12,454 patients) were enrolled in this study. Participants were followed up from the first reported dialysis date to the date of death or end of dialysis by December 31, 2015. Setting Data collection was conducted in Taiwan. Results A total of 2633 and 9821 patients were classified into the RCT and non-RCT groups, respectively. From the data of Taiwan’s National Health Insurance, a total of 5,092,734 teeth received RCT from 2000 to 2015. Then, a total of 12,454 patients were followed within the 16 years, and 4030 patients passed away. The results showed that members of the non-RCT group (34.93%) had a higher mortality rate than those of the RCT group (22.79%; p = 0.001). The multivariate-adjusted hazard ratio for the risk of death was 0.69 (RCT vs. non-RCT; p = 0.001). Conclusions This study suggested that patients who had received RCT had a relatively lower risk of death among dialysis patients. Infectious diseases had a significant role in mortality among dialysis patients with non-RCT. Appropriate interventions for dental problems may increase survival among dialysis patients. Abbreviations: CKD = chronic kidney disease, ESRD = end-stage renal disease, RCT = root canal therapy.


2008 ◽  
Vol 74 (9) ◽  
pp. 1178-1184 ◽  
Author(s):  
Fredric O. Finkelstein ◽  
Kenneth Story ◽  
Catherine Firanek ◽  
Paul Barre ◽  
Tomoko Takano ◽  
...  

2018 ◽  
Vol 40 (2) ◽  
pp. 130-135 ◽  
Author(s):  
Luana Rodrigues Sarmento ◽  
Paula Frassinetti Castelo Branco Camurça Fernandes ◽  
Marcelo Ximenes Pontes ◽  
Daniel Barros Santos Correia ◽  
Victhor Castelo Branco Chaves ◽  
...  

ABSTRACT Introduction: Knowledge of validated primary causes of end-stage renal disease (ESRD) is extremely relevant in the realm of public health. The literature lacks validated studies on the primary causes of ESRD. Objective: The aim of this study was to estimate the prevalence of the causes of ESRD in a State Capital in Northeastern Brazil. Methods: This cross-sectional study was based on the analysis of medical records of patients on hemodialysis at five specialized centers in Fortaleza, CE, Brazil. Deaths and patients referred to other centers outside Fortaleza were excluded from the study. The data of 830 patients were initially collected, but 818 remained enrolled after the exclusion criteria were applied, the equivalent to 48% of the patents on dialysis in the city. Results: 61.1% of the patients were males. Twenty-two percent of all enrolled individuals were aged 60-69 years. Patient mean age was 55.7 ± 16 years. The most common validated cause of ESRD was unknown (35.3%), followed by diabetes mellitus (26.4%), adult polycystic kidney disease (6.2%), graft failure (6.2%), obstructive uropathy (5.7%), and primary glomerulonephritis (5.3%). Before validation, primary hypertension was the most frequent cause of chronic kidney disease (22.9%), decreased to 3.8% after validation. Conclusion: The data contradicted national studies reporting primary hypertension as the main cause of chronic kidney disease (CKD). A high rate of unknown causes and categorization bias were observed mainly in relation to primary hypertension as a cause of CKD, which affects the overall prevalence of causes of ESRD in patients on dialysis.


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