primary hypertension
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2022 ◽  
Vol 2022 (1) ◽  
Author(s):  
Gabriela Cormick ◽  
Agustín Ciapponi ◽  
María Luisa Cafferata ◽  
María Sol Cormick ◽  
José M Belizán

Author(s):  
Éva K. Lakatos ◽  
◽  
Emese Lukács ◽  
Septimiu Voidăzan ◽  
Aurel Nireștean ◽  
...  

2021 ◽  
Author(s):  
Li Junhua ◽  
Wu Minjuan ◽  
Feng Guohe ◽  
Zhang Xingwei ◽  
Wang Wenqin

Abstract Intuitive eating (IE) is largely considered to be engaging in behaviors consistent with eating in reaction to one’s physiological appetite and fullness signals instead of environmental stimuli and emotional cues. The Intuitive Eating Scale-2 (IES-2) was developed in order to assess the outlook and behaviors of eating on four subscales: unconditional permission to eat (UPE), eating because of physiological as opposed to emotional reasons (EPR), dependence on physiological hunger and satiety cues (RHSC), and body-food choice congruence (B-FCC). Obesity is a frequent comorbidity in Chinese patients with hypertension and nearly 3/4 of such patients have eating problems. The current study intended to validate the psychological measurement properties of the IES-2 Chinese Version (IES-2-Chi) in an obese population with hypertension. For the IES-2-Chi, Cronbach's ɑ = 0.947, split-half reliability was 0.850, the test-retest reliability was 0.889, chi-square/degree of freedom ratio (χ2/df) = 1.318, root mean square error approximation (RMSEA) = 0.040, root mean square residual (RMR) = 0.053, goodness-of-fit index (GFI) = 0.902, comparative fit index (CFI) = 0.982, Tucker-Lewis index (TLI) = 0.978, incremental fit index (IFI) = 0.983, and normal fit index (NFI) = 0.932. The secondary study objective was to evaluate IE levels of obese Chinese patients with hypertension. IE was correlated positively with self-efficacy, body image, and frequency of eating vegetables and fruits, but negatively with body mass index, hemoglobin, diastolic blood pressure, hematocrit, total cholesterol, low-density lipoprotein, and frequency of eating fast food.Conclusion: The current study demonstrates that the IES-2-Chi has good reliability and validity in obese patients with primary hypertension and can be used to evaluate IE levels of these patients. Based on the current study results, future studies may be designed to develop intervention strategies using IE to utilize its influential factors in obese patients with primary hypertension.


Author(s):  
Izabela Kubiszewska ◽  
Lidia Gackowska ◽  
Łukasz Obrycki ◽  
Aldona Wierzbicka ◽  
Anna Helmin-Basa ◽  
...  

2021 ◽  
Vol 56 (4) ◽  
pp. 431-438
Author(s):  
Trung Kien NGUYEN ◽  
◽  
Duy Linh NGUYEN ◽  
Thi Tuyet Ngan DOAN ◽  
Hong Ha NGUYEN ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Shuai Zheng ◽  
Chunmei Piao ◽  
Yan Liu ◽  
Xuxia Liu ◽  
Tingting Liu ◽  
...  

Increasing evidences suggest that the gut microbiota have their contributions to the hypertension, but the metagenomic characteristics and potential regulating mechanisms in primary hypertension patients taking antihypertension drugs are not clear yet. We carried out a metagenomic analysis in 30 primary hypertension patients taking antihypertension medications and eight healthy adults without any medication. We found that bacterial strains from species, such as Bacteroides fragilis, Bacteroides vulgatus, Escherichia coli, Klebsiella pneumoniae, and Streptococcus vestibularis, were highly increased in patients; and these strains were reported to generate glycan, short-chain fatty acid (SCFA) and trimethylamine (TMA) or be opportunistic pathogens. Meanwhile, Dorea longicatena, Eubacterium hallii, Clostridium leptum, Faecalibacterium prausnitzii, and some other strains were greatly decreased in the patient group. The Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis found that ortholog groups and pathways related to glycan biosynthesis and multidrug resistance were significantly increased in the patient group, and some of the hub genes related to N-glycan biosynthesis were increased in the patient group, while those related to TMA precursor metabolism and amino acid metabolism both increased and decreased in the patient group. Metabolites tested by untargeted liquid chromatography–mass spectrometry (LC-MS) proved the decrease of acetic acid, choline, betaine, and several amino acids in patients’ fecal samples. Moreover, meta-analysis of recent studies found that almost all patients were taking at least one kind of drugs that were reported to regulate adenosine monophosphate-activated protein kinase (AMPK) pathway, so we further investigated if AMPK regulated the metagenomic changes by using angiotensin II-induced mouse hypertensive model on wild-type and macrophage-specific AMPK-knockout mice. We found that the changes in E. coli and Dorea and glycan biosynthesis-related orthologs and pathways were similar in our cohort and hypertensive wild-type mice but reversed after AMPK knockout. These results suggest that the gut microbiota-derived glycan, SCFA, TMA, and some other metabolites change in medication-taking primary hypertension patients and that medications might promote gut microbiota glycan biosynthesis through activating macrophage-AMPK.


2021 ◽  
Vol Volume 15 ◽  
pp. 4489-4502
Author(s):  
Xuanxuan Liu ◽  
Xingxing Wang ◽  
Yan Pan ◽  
Li Zhao ◽  
Shuo Sun ◽  
...  
Keyword(s):  

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Alviani Latifah Fuat ◽  
Fajar Susanti ◽  
Erlin Ifadah

Changes in human development at this time greatly affect lifestyles it is a cause of an increase in non- communicable diseases (PTM) one of which is hypertension. Hypertension control has been pursued by the government by implementing a chronic disease prevention program (PROLANIS) through collaboration with BPJS. This study aims to determine the difference in blood pressure reduction in primary hypertension patients who follow prolanis and non prolanis in the Cipayung District Health Center. Pre-experimental research design with static group comparison research. The study population was primary hypertension patients who followed prolanis and non prolanis in the Cipayung District Health Center. Samples were taken by purposive sampling and found 40 people. The collected data is tested statistically by T-test. The results of the study of primary hypertension patients who follow Prolanis have better blood pressure. Statistical test results showed there were differences in blood pressure reduction in primary hypertension patients who followed prolanis and non prolanis (p = 0,000, p <0.05). Nurses provide education to primary hypertension patients who have not yet joined the program to participate in the PROLANIS program.Keyword: Hypertension, Blood Pressure, PROLANIS


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