scholarly journals Microbiology of Urinary Tract Infection and the Status of Urinary Isolates in Pregnant Women

2015 ◽  
Vol 13 (2) ◽  
pp. 20-24
Author(s):  
Sharmila Parajuli ◽  
B Thapa
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Asymptomatic Bacteriuria ◽  
Antibiotic Sensitivity ◽  
First Trimester ◽  
Number Of Patients ◽  
Sensitivity Pattern ◽  
Culture Positive

Introduction: Urinary tract infection (UTI) is one of the most frequently encountered problems owing to significant number of patients needing hospitalization during pregnancy. The incidence of UTI in pregnant women is reported to be high up to 7-8%.Methods: This is a prospective study conducted in Valley Maternity Hospital during a period of 6 months (Jan 2011 to June 2011). 520 MSU (Mid stream urine samples) from pregnant women clinically suspected of urine infection were evaluated by urine dipstick analysis, microscopic and culture method. The isolates were identified and antibiotic sensitivity pattern was determined by standard protocol.Results: The majority of the patients were in-between the age group of 20-30years- 338cases (65%) and these patients usually presented in the first trimester of pregnancy- 317cases (60.96%).  Out of the 520 clinically suspected UTI cases, 232 (44.61%) was culture positive. Out of the culture positive cases; Escherichia coli (E.coli) was the most common accounting for a total of 144cases (80%). Nitrofurantoin was found to be the most effective drug against the gram negative (Gm-ve) bacteria. Similarly, Ampicillin, Amoxycillin and Cloxacillin were found to be effective agent against gram positive (Gm+ve) bacteria.Conclusions: Screening for bacteriuria is recommended among all pregnant women at the first prenatal visit and in the subsequent trimesters of pregnancy. Prompt treatment of symptomatic UTI and asymptomatic bacteriuria is required in pregnant women to avoid complications like preterm birth, low birth weight and increased perinatal mortality.

scholarly journals Study on microbiology of urinary tract infection and the status of urinary isolates in pregnant women

2015 ◽  
Vol 12 (2) ◽  
Author(s):  
Sharmila Parajuli
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Asymptomatic Bacteriuria ◽  
Culture Method ◽  
First Trimester ◽  
Number Of Patients ◽  
Sensitivity Pattern ◽  
Culture Positive

<!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> <w:UseAsianBreakRules /> <w:DontGrowAutofit /> <w:UseFELayout /> </w:Compatibility> <w:BrowserLevel>MicrosoftInternetExplorer4</w:BrowserLevel> </w:WordDocument> </xml><![endif]--> <p class="MsoNormal" style="text-align: justify; text-justify: inter-ideograph; line-height: 200%; tab-stops: 78.0pt;"><strong style="mso-bidi-font-weight: normal;">Background:</strong> Urinary tract infection (UTI) is one of the most frequently encountered problems owing to significant number of patients needing hospitalization during pregnancy. The incidence of UTI in pregnant women is reported to be high up to 7-8%.</p> <p class="MsoNormal" style="text-align: justify; text-justify: inter-ideograph; line-height: 200%; tab-stops: 78.0pt;"><strong style="mso-bidi-font-weight: normal;">Materials and methods: </strong>This is a prospective study conducted in Valley Maternity Hospital during a period of 6 months (Jan 2011 to June 2011). 520 MSU (Mid stream urine samples) from pregnant women clinically suspected of urine infection were evaluated by urine dipstick analysis, microscopic and culture method. The isolates were identified and antibiotic sensitivity pattern was determined by standard protocol.</p> <p class="MsoNormal" style="text-align: justify; text-justify: inter-ideograph; line-height: 200%; tab-stops: 78.0pt;"><strong style="mso-bidi-font-weight: normal;">Results: </strong>The majority of the patients were in-between the age group of 20-30years- 338cases (65%) and these patients usually presented in the first trimester of pregnancy- 317cases (60.96%). <span style="mso-spacerun: yes;">&nbsp;</span>Out of the 520 clinically suspected UTI cases, 232 (44.61%) was culture positive. Out of the culture positive cases; Escherichia coli (E.coli) was the most common accounting for a total of 144cases (80%). Nitrofurantoin was found to be the most effective drug against the gram negative (Gm-ve) bacteria. Similarly, Ampicillin, Amoxycillin and Cloxacillin were found to be effective agent against gram positive (Gm+ve) bacteria.</p> <p class="MsoNormal" style="text-align: justify; text-justify: inter-ideograph; line-height: 200%; tab-stops: 78.0pt;"><strong style="mso-bidi-font-weight: normal;">Conclusion: </strong>Screening for bacteriuria is recommended among all pregnant women at the first prenatal visit and in the subsequent trimesters of pregnancy. Prompt treatment of symptomatic UTI and asymptomatic bacteriuria is required in pregnant women to avoid complications like preterm birth, low birth weight and increased perinatal mortality.</p> <p class="MsoNormal" style="text-align: justify; text-justify: inter-ideograph; line-height: 200%; tab-stops: 78.0pt;"><span style="text-decoration: underline;">Key words</span>: UTI, Pregnant women, Antibiotics, Culture method.</p> <!--[if gte mso 9]><xml> <w:LatentStyles DefLockedState="false" LatentStyleCount="156"> </w:LatentStyles> </xml><![endif]--><!--[if !mso]><object classid="clsid:38481807-CA0E-42D2-BF39-B33AF135CC4D" id=ieooui></object> <style> st1\:*{behavior:url(#ieooui) } </style> <![endif]--><!--[if gte mso 10]> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;} </style> <![endif]-->

scholarly journals The study of antibiotic-sensitivity and resistance pattern of bacteria causing catheter associated urinary tract infection

2020 ◽  
Vol 9 (8) ◽  
pp. 3196
Author(s):  
Abha Singh ◽  
Avinashi Kujur ◽  
Muthu Lakshmi M. ◽  
Abha Daharwal
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Asymptomatic Bacteriuria ◽  
Antibiotic Sensitivity ◽  
Multidrug Resistant ◽  
Resistance Pattern ◽  
Sensitivity Testing ◽  
Sensitivity Pattern ◽  
The Cost

Background: present study is done to study the antibiotic-sensitivity and resistance pattern of bacteria causing catheter associated urinary tract infection. Objectives of this study were to study the bacterial etiology of CAUTI, to study the prevalence of various bacteria causing catheter associated urinary tract infection, the antibiogram (sensitivity and resistance) pattern of isolated bacteria and the percentage of asymptomatic bacteriuria in the study population.Methods: In this prospective observational study, under aseptic precautions, urine sample was taken after 48 hours of catheterization and sent for culture and sensitivity pattern is studied.Results: In this study 500 urine samples were cultured and its antibiotic sensitivity pattern was observed. Out of the 53 culture positive samples most the subjects had asymptomatic bacteriuria. The study gave the incidence of catheter associated urinary tract infection (CAUTI) to be 10.6% and about 9% were polymicrobial. In this study about 7 causative bacteria were isolated. Escherichia coli were the most common organism that was isolated. On studying the antibiotic susceptibility pattern of each isolate, it has been observed that all of them are multidrug resistant and the sensitivity pattern is migrating towards higher antibiotics.Conclusions: Empirical use of antibiotics must be avoided and antibiotics must be used only after sensitivity testing. This will help in selection of the appropriate antibiotic for therapeutic use and prevent indiscriminate and irrational use of antibiotics. This will also improve the cost efficiency and decrease the duration of hospital stay.

scholarly journals Recent Antibiotic Sensitivity Pattern of Escherichia Coli in Urinary Tract Infection

2018 ◽  
Vol 30 (1) ◽  
pp. 61-65
Author(s):  
Md Abdul Bari ◽  
Mashiur Arefin ◽  
Moriom Nessa ◽  
Golam Mostofa ◽  
Tafiqul Islam
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urine Culture ◽  
Antibiotic Sensitivity ◽  
E Coli ◽  
Sensitivity Pattern ◽  
Marked Resistance ◽  
Culture Positive

The objective of the study is to assess the recent sensitivity pattern of Escherichia coli in Urinary tract infection (UTI). Widespread use of antibiotics has led to the emergence of resistant microorganisms. As the antibiotic sensitivity patterns of the microorganisms are frequently changing, this retrospective analysis was designed to assess the recent antibiotic sensitivity pattern of Escherichia coli (E. coli) in urinary tract infection among the human population. Details of 358 urine culture positive reports for E. coli and their antibiotic sensitivity pattern pertaining to the study period of 6 months from Jan 2017 to June 2017 were collected from Microbiology Laboratory of Diagnostic Centers at Rajshahi and the results were statistically analyzed. The antibiotics tested for sensitivity were amikacin, gentamycin, ciprofloxacin, levofloxacin, cotrimoxazole, nitrofurantoin, ceftazidime, ceftriaxone and cefixime. The sensitivity pattern of E.coli to antibiotics in UTI was amikacin (82.68 gentamycin (75.97%), nitrofurantoin (70.67), levofloxacin (44.13%), ceftazidime (42.17%), co-trimoxazole (40.78%), ceftriaxone (38.54%), ciprofloxacin (35.75%), and cefixime (24.02%). The study highlighted the marked resistance of E. coli to quinolones and third generation cephalosporins.TAJ 2017; 30(1): 61-65

scholarly journals Antibiotic Sensitivity in UTI among Diabetic Pregnant Women

2020 ◽  
Vol 33 (1) ◽  
pp. 54-58
Author(s):  
N Naher ◽  
F Begum ◽  
N Hashem
Keyword(s):  
Diabetes Mellitus ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Standard Procedure ◽  
Antibiotic Sensitivity ◽  
Successful Outcome ◽  
E Coli ◽  
Sensitivity Pattern

Background: Urinary tract infection (UTI) is common during pregnancy and especially soin pregnant patients with diabetes mellitus. The emergence of drug resistance and particularlythe extended spectrum Beta-lactamase production by Escherechia Coli and Methicillinresistance in staphylococci, limits the choice of anti-microbials. Method: A cross-sectional study was conducted on 50 pregnant women with sign andsymptoms of UTI in the Department of Obstetrics and Gynaecology, BIRDEM generalHospital-2 from January to June 2017. The objectives of the study were to determine thepresence and type of pathogens found in pregnant diabetic women presenting with featuresof urinary tract infection, and to analyze their antibiotic sensitivity pattern. Clean catch midstreamurine samples were collected using standard procedure and culture and sensitivitywas done following standard bacteriological method. Results: Mean age of the study subjects was 29.84±5.29 yrs; 48% were in third trimester ofpregnancy; 52% had Gestational Diabetes Mellitus (GDM) and 48% had Diabetes Mellitus(DM). Out of fifty pregnant women, thirty eight (76.0%) study subjects had positive growth.Of them, Escherechia coli was found in 57.9% cases, Klebsiellain 21.1%, Staphylococcusaureus in 7.9%, Enterococcus and Pseudomonas aeruginosa each in 2.6% case. Amikacinwas found to be sensitive to 100% cases of E. Coli, Klebsiella& Enterococcus but 100%resistant to Streptococcus. Conclusion: In this study, E. Coli was the most common organisms causing UTI, which isless susceptible to conventional oral antibiotics but more susceptible to amikacin. So carefulldrug selection is required for successful outcome in UTI. Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1) : 54-58

scholarly journals Frequency of Extended-Spectrum Beta-Lactamase Producing Organisms Causing Urinary Tract Infection and Their Antibiotic Sensitivity Pattern

2017 ◽  
Vol 18 (1) ◽  
pp. 3-5
Author(s):  
Md Raziur Rahman ◽  
Muhammad Abdur Rahim ◽  
Samira Rahat Afroze ◽  
Chinmay Shaha Poddar ◽  
Khwaja Nazim Uddin
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Antibiotic Sensitivity ◽  
Beta Lactamase ◽  
Extended Spectrum Beta Lactamase ◽  
E Coli ◽  
Extended Spectrum ◽  
Number Of Patients ◽  
Sensitivity Pattern

Background: The spectrum of bacteria causing urinary tract infection (UTI) and their antibiotic sensitivity pattern is not uniform. Escherichia coli and Klebsiella sp. are two common organisms responsible for UTI through-out the world. The incidence of UTI due to infection with extended-spectrum beta-lactamase (ESBL) producing organisms are increasing. This study was aimed to describe the frequency of ESBL positive organisms causing UTI and their antibiotic sensitivity pattern.Methods: This cross-sectional study was done in the Department of Internal Medicine, BIRDEM General Hospital from January to April, 2016.Results: Total number of patients was 137 with females predominance (M:F ratio 1 : 3.7). Mean age was 60.3 ±11.7 years. Most patients (131, 95.6%) of the study population were diabetic and glycaemic control was poor (mean HbA1c 9.3 ±2.3) in these subjects. Common symptoms were fever, vomiting, increased urinary frequency, dysuria, suprapubic pain, and loin pain. Neutrophilic leukocytosis was common (94.9%). E. coli (73.7%) was the commonest aetiological agent followed by Klebsiella (8.8%), Enterococcus (4.4%), Citrobacter (3.6%), Staphylococcus aureus (3.6%), Acinetobacter (2.9%), Enterobacter (1.5%), and Pseudomonas (1.5%). Over half of E. coli and of Klebsiella sp. and 100% of Enterobacter organisms were ESBL positive. Imipenem (100%), amikacin, netilmycin,and nitrofurantoin were among the most sensitive antibiotics.Conclusion: More than half (71, 51.82%) of UTI cases were due to ESBL positive organisms. Imipenem, amikacin, netilmycin, and nitrofurantoin remain the drug of choice.J MEDICINE January 2017; 18 (1) : 3-5

scholarly journals POLA BAKTERI DAN TES KEPEKAAN ANTIBIOTIKA WANITA HAMIL DENGAN BAKTERIURIA ASIMTOMATIS

2018 ◽  
Vol 12 (3) ◽  
pp. 103
Author(s):  
L. P. Kalalo ◽  
Aryati . ◽  
B. Subagjo
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Clavulanic Acid ◽  
Low Birthweight ◽  
Asymptomatic Bacteriuria ◽  
Antibiotic Sensitivity ◽  
Antibiotic Susceptibility Test ◽  
Amoxicillin Clavulanic Acid

Asymptomatic bacteriuria is defined as bacteriuria consisting of one type of bacteria ³ 105 CFU/mL in clean-voided midstreamculture of a person without any symptoms of urinary tract infection. Untreated asymptomatic bacteriuria is dangerous for pregnancybecause complications such as pyelonephritis, maternal sepsis, premature birth, and premature rupture of the membrane, low birthweight baby, hypertension and or preeclampsia, anaemia in pregnancy, amnionitis and post delivery endometriosis can arise. Someasymptomatic cases could threaten the pregnant woman and her foetus without prior pyelonephritis symptoms. The purpose of this studywas to determine the pattern of bacteria in asymptomatic bacteriuria pregnant women and their antibiotic sensitivity. This study hasbeen carried out between October 2003 and April 2004 on 376 pregnant women without symptoms of urinary tract infection. Screeningwas performed using urine culture, followed by antibiotic susceptibility test. The study showed that the prevalence of asymptomaticbacteriuria among pregnant women in RSU Dr. Soetomo was 9.85% (37 out of 376 pregnant women without urinary tract infection).Thirteen bacterial types were found in those 37 positive samples. The most common bacteria found was Escherichia coli (37.83%). Thisbacterium was sensitive to ceftriaxone (85.71%), nitrofurantoin (64.28%) and amoxicillin-clavulanic acid (57.14%). Based on the datagained in this study, it is concluded that the prevalence of pregnancy cases with asymptomatic bacteriuria in the Dr. Soetomo Hospitalis significantly high (9.85%). The most recommended drugs are ceftriaxone, amoxicillin-clavulanic acid and nitrofurantoin.

scholarly journals Antibiotic Sensitivity of Pathogens Causing Urinary Tract Infection

2013 ◽  
Vol 16 (1) ◽  
pp. 53-58 ◽  
Author(s):  
Taslima Akter ◽  
Zakaria Mia ◽  
Masum Shahriar
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Age Groups ◽  
Antibiotic Sensitivity ◽  
Pharmaceutical Journal ◽  
Reproductive Age ◽  
Mueller Hinton ◽  
Sensitivity Pattern ◽  
Mueller Hinton Agar

Diagnosis of urinary tract infection (UTI) causing pathogens with their sensitivity to different antibiotics was performed with a total of 96 samples from both male (n=31; 32.3%) and female (n=65; 67.7%) of different age groups. Out of 96 urine samples, 55 (57.3%) were found positive after culturing in MacConkey agar plates. The percent distribution of positive cases against collected samples was higher for female (67%) than male (32%). However, female and male at the reproductive age of 16-30 years were more susceptible to UTI. A total of 55 bacterial isolates were identified by conventional methods and their antibiotic sensitivity was tested using Mueller- Hinton agar plates. The predominant isolates were Escherichia coli (34.5%), Klebsiella sp. (18.2%) and Staphylococci (20.0%). The sensitivity pattern for most of the isolated organisms showed 50% and/or higher sensitivity to imipenem, azithromycin and cephalexin, except Staphylococci (only 9.09% to azithromycin). DOI: http://dx.doi.org/10.3329/bpj.v16i1.14491 Bangladesh Pharmaceutical Journal 16(1): 53-58, 2013

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