scholarly journals Melanocytoma of the optic disc – a case report

2012 ◽  
Vol 4 (2) ◽  
pp. 323-325 ◽  
Author(s):  
H Sharma ◽  
L R Puri
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Visual Impairment ◽  
Fluorescein Angiography ◽  
Optic Disc ◽  
Benign Lesion ◽  
Fundus Examination ◽  
The Right

Introduction: Melanocytoma of the optic disc is a benign lesion. Objective: To describe a case of optic disc melanocytoma Case: A 48-year old lady presented with gradual visual impairment associated with a floater. The right eye fundus examination showed a mass uniformly dark black in colour on the optic disc. The mass completely obscured the fluorescence on fluorescein angiography and was thus differentiated from malignant melanoma. Conclusion: Optic disc melanocytoma can present with visual impairment and a floater. Fluorescein angiography can be useful to differentiate between malignDOI: http://dx.doi.org/10.3126/nepjoph.v4i2.6553 Nepal J Ophthalmol 2012; 4 (2): 323-325

scholarly journals Unilateral visual impairment in a patient undergoing chemotherapy: a case report and clinical findings

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Xia Yuan ◽  
Yuliang Feng ◽  
Dan Li ◽  
Mei Li
Keyword(s):  
Visual Acuity ◽  
Visual Impairment ◽  
Fluorescein Angiography ◽  
Optic Disc ◽  
Vision Loss ◽  
Fundus Photograph ◽  
Fundus Fluorescein Angiography ◽  
Intravenous Chemotherapy ◽  
Normal Dose ◽  
The Right

Abstract Background Visual impairment occurred as an infrequent form of chemotherapeutic toxicity and was often underestimated despite of several reports. We described a case of acute unilateral visual impairment after one cycle of intravenous chemotherapy of a normal dose, aiming at raising attention to chemotherapy-induced ocular toxicity. Case presentation The patient developed a progressive vision loss in the right eye during the chemotherapy. After one cycle of intravenous chemotherapy, her visual acuity decreased by 0.6 in the right eye (VOD = 0.4) compared to the previous value of 1.0 (VOD = 1.0). No evidence of ocular infiltration was observed from the cerebral magnetic resonance imaging (MRI). During her follow-up period, we documented the ophthalmologic examinations including visual acuity, visual field (VF), visual evoked potential (VEP), electroretinogram (ERG), fundus photograph (FP), fundus fluorescein angiography (FFA) and optical coherence tomography (OCT). Ophthalmoscope examination and fundus photograph showed optic disc edema, fuzzy boundary and linear hemorrhages in her right eye. Fundus fluorescein angiography (FFA) revealed capillary underdevelopment at the nasal and superior temporal area of the optic disc in the early phase and capillary fluorescein leakage in the late phase. The result of VEP test suggested the impaired function of the optic nerve. Thus, a diagnosis of nonarteritic anterior ischemic optic neuropathy (NAION) was made by the ophthalmologist according to these results. The patient was prescribed prednisone combined with neuroprotective drugs, which did not work. After the cessation of chemotherapy, her impaired vision gradually recovered. Conclusions This is the first reported case of acute visual impairment in a patient who underwent chemotherapy of a normal dose. It is indicated that while receiving benefits from chemotherapy, cancer patients simultaneously suffer from the risk of vision loss.

scholarly journals Monocular visual impairment in a patient undergoing cisplatin-based chemotherapy: a case report and clinical findings

2019 ◽  
Author(s):  
Xia Yuan ◽  
Yuliang Feng ◽  
Dan Li ◽  
Mei Li
Keyword(s):  
Visual Impairment ◽  
Fluorescein Angiography ◽  
Optic Disc ◽  
Vision Loss ◽  
Ischemic Optic Neuropathy ◽  
Fundus Photograph ◽  
Fundus Fluorescein Angiography ◽  
Cerebral Magnetic Resonance Imaging ◽  
Normal Dose ◽  
The Right

Abstract Background Visual impairment occurred as an infrequent form of chemotherapeutic toxicity and was often underestimated despite of several reports. We described a case of acute monocular visual impairment after one cycle of intravenous cisplatin-based chemotherapy of normal dose, aimed at raising attention to chemotherapy-induced ocular toxicity. Case presentation The patient consulted to an ophthalmologist, and during her follow-up period we documented the ophthalmologic examinations including visual acuity, visual field (VF), visual evoked potential (VEP), electroretinogram (ERG), fundus photograph (FP), fundus fluorescein angiography (FFA) and optical coherence tomography (OCT). During chemotherapy, the patient developed progressive vision loss in the right eye. No evidence of ocular infiltration was observed from the cerebral magnetic resonance imaging (MRI). Ophthalmoscope examination and fundus photograph showed optic disc edema, fuzzy boundary and linear hemorrhages in the right eye. Fundus fluorescein angiography (FFA) revealed capillary underdevelopment at the nasal and superior temporal area of optic disc in the early phase and capillary fluorescein leakage in the late phase. The result of VEP test suggested that the function of optic nerve was impaired. A diagnosis of nonarteritic anterior ischemic optic neuropathy (NAION) was made by an ophthalmologist and the patient received prednisone combined with neuroprotective drugs, which did not work. After cessation of chemotherapy, her impaired vision gradually improved. Conclusions This is the first reported case of acute visual impairment in a patient undergoing cisplatin-based chemotherapy of normal dose. It is warranted that cancer patients benefiting from chemotherapy simultaneously suffer from the risk of vision loss.

scholarly journals Unilateral visual impairment in a patient undergoing chemotherapy: a case report and clinical findings

2019 ◽  
Author(s):  
Xia Yuan ◽  
Yuliang Feng ◽  
Dan Li ◽  
Mei Li
Keyword(s):  
Visual Acuity ◽  
Visual Impairment ◽  
Fluorescein Angiography ◽  
Optic Disc ◽  
Vision Loss ◽  
Fundus Photograph ◽  
Fundus Fluorescein Angiography ◽  
Intravenous Chemotherapy ◽  
Normal Dose ◽  
The Right

Abstract Background: Visual impairment occurred as an infrequent form of chemotherapeutic toxicity and was often underestimated despite of several reports. We described a case of acute unilateral visual impairment after one cycle of intravenous chemotherapy of normal dose, aimed at raising attention to chemotherapy-induced ocular toxicity. Case presentation: During chemotherapy, the patient developed progressive vision loss in the right eye. She had worse visual acuity of 0.4 in the right eye (VOD0.4) than before (VOD1.0) after one cycle of intravenous chemotherapy. No evidence of ocular infiltration was observed from the cerebral magnetic resonance imaging (MRI). During her follow-up period we documented the ophthalmologic examinations including visual acuity, visual field (VF), visual evoked potential (VEP), electroretinogram (ERG), fundus photograph (FP), fundus fluorescein angiography (FFA) and optical coherence tomography (OCT). Ophthalmoscope examination and fundus photograph showed optic disc edema, fuzzy boundary and linear hemorrhages in the right eye. Fundus fluorescein angiography (FFA) revealed capillary underdevelopment at the nasal and superior temporal area of optic disc in the early phase and capillary fluorescein leakage in the late phase. The result of VEP test suggested that the function of optic nerve was impaired. A diagnosis of nonarteritic anterior ischemic optic neuropathy (NAION) was made by an ophthalmologist and the patient received prednisone combined with neuroprotective drugs, which did not work. After cessation of chemotherapy, her impaired vision gradually improved. Conclusions: This is the first reported case of acute visual impairment in a patient undergoing chemotherapy of normal dose. It is warranted that cancer patients benefiting from chemotherapy simultaneously suffer from the risk of vision loss.

scholarly journals Multinodular and Vacuolating Neuronal Tumor

2018 ◽  
Vol 6 (9) ◽  
pp. 1697-1698 ◽  
Author(s):  
Charmaine Zahra ◽  
Reuben Grech
Keyword(s):  
Case Report ◽  
Brain Imaging ◽  
Temporal Lobe ◽  
Benign Lesion ◽  
Occipital Lobe ◽  
Imaging Findings ◽  
Cns Tumours ◽  
The Right ◽  
Rare Diagnosis ◽  
Neuronal Tumor

BACKGROUND: Multinodular and Vacuolating Neuronal Tumor (MVNT) of the cerebrum is a benign lesion described recently in the WHO CNS tumours in 2016. Although this tumour is uncommon, clinicians should be acquainted with the possible presentation and imaging findings. CASE REPORT: We present a case of a young gentleman whose only symptom was absence seizures. Brain imaging showed lesions, compatible with this rare diagnosis. CONCLUSION: Our description of imaging findings on MRI highlights the characteristic cystic appearances of note in the right occipital lobe, in contrast to the temporal lobe as the predominant location found in previous cases.

scholarly journals A 5-Year-Old Case of Choroidal Neovascularization in Enhanced S-Cone Syndrome Treated with Ranibizumab

2018 ◽  
Vol 9 (3) ◽  
pp. 510-515 ◽  
Author(s):  
Federica Bertoli ◽  
Silvia Pignatto ◽  
Francesca Rizzetto ◽  
Paolo Lanzetta
Keyword(s):  
Case Report ◽  
Fluorescein Angiography ◽  
Choroidal Neovascularization ◽  
Subretinal Fluid ◽  
Intravitreal Ranibizumab ◽  
Genetic Studies ◽  
Visual Deterioration ◽  
Retinal Degenerations ◽  
The Right ◽  
Enhanced S Cone Syndrome

Introduction: We describe the youngest case of enhanced S-cone syndrome (ESCS) associated with choroidal neovascularization (CNV) successfully treated with intravitreal ranibizumab injections. Case Report: A 5-year-old boy presented with round-shaped fibrotic subretinal lesions in both eyes with surrounding subretinal fluid and progressive visual deterioration in the right eye. Fine foci of increased autofluorescence were observed along the arcades in both eyes. Fluorescein angiography revealed the presence of CNV in his right eye, and treatment with ranibizumab was initiated, with significant improvement in vision. Subsequent electroretinogram examination and genetic studies of the patient and his two younger siblings confirmed the diagnosis of ESCS. Conclusion: CNV has been reported to occur in different inherited retinal degenerations, including ESCS. Our experience confirms that treatment with ranibizumab in patients with CNV-complicated ESCS can be potentially vision-saving.

scholarly journals Exudative Type 3 Retinal Arteriovenous Malformation in a Pediatric Patient

2018 ◽  
Vol 9 (3) ◽  
pp. 504-509
Author(s):  
Helena Dens ◽  
Ingele Casteels
Keyword(s):  
Optical Coherence Tomography ◽  
Differential Diagnosis ◽  
Arteriovenous Malformation ◽  
Fluorescein Angiography ◽  
Optic Disc ◽  
Optical Coherence Tomography Angiography ◽  
Imaging Techniques ◽  
Optical Coherence ◽  
The Right ◽  
Type 3

We describe a 7-year-old girl who developed exudation nasally to the right optic disc due to retinal arteriovenous malformation. Fluorescein angiography, spectral domain optical coherence tomography, and optical coherence tomography angiography were performed. We give an overview of the different imaging techniques and discuss the differential diagnosis. Since there was no visual impairment, no treatment was started. A spontaneous decrease in edema and exudation was noted after 6 months.

scholarly journals Optic nerve head retinal artery macroaneurysm: Report of a case

2019 ◽  
Vol 7 ◽  
pp. 2050313X1986947
Author(s):  
Ramesh Venkatesh ◽  
Prachi Gurav
Keyword(s):  
Optic Nerve ◽  
Fluorescein Angiography ◽  
Optic Disc ◽  
Optic Nerve Head ◽  
Hypertensive Retinopathy ◽  
Fundus Examination ◽  
Elderly Male ◽  
Spontaneous Involution ◽  
Retinal Artery ◽  
Retinal Artery Macroaneurysm

A 61-year-old elderly male, hypertensive patient presented to the retina clinic with sudden drop in vision in the left eye for 6 days. His best-corrected visual acuity at presentation was counting fingers close to face. Fundus examination of the left eye revealed the presence of subretinal and preretinal haemorrhage at the macula along with hypertensive retinopathy changes in both eyes. Fluorescein angiography was done, which showed a retinal artery macroaneurysm at the optic nerve head. Optical coherence tomogram through the optic nerve head also confirmed the presence of retinal artery macroaneurysm. The patient was treated with injection of 0.4 cc of 100% C3F8 to displace the blood off the macula. At final follow-up visit at 2 months post treatment, his vision improved to 6/12, N8. Fundus examination showed a small residual altered blood nasal to the fovea. No treatment was however done to the retinal artery macroaneurysm due to its atypical location and chance of spontaneous involution. In conclusion, retinal artery macroaneurysm at the optic disc is extremely uncommon. Identification of the retinal artery macroaneurysm lesion is more difficult in glaucoma patients due to the large and deep optic cup. Fluorescein angiography remains the main investigative modality to confirm the diagnosis. Spontaneous involution still remains the mainstay of treatment in optic disc retinal artery macroaneurysm.

scholarly journals Mesenchymal hamartoma of the liver in adults: Case report

2014 ◽  
Vol 67 (11-12) ◽  
pp. 399-403 ◽  
Author(s):  
Tanja Lakic ◽  
Mirjana Zivojinov ◽  
Milivoje Vukovic ◽  
Jelena Ilic-Sabo ◽  
Tamara Boskovic
Keyword(s):  
Case Report ◽  
Cystic Lesion ◽  
Benign Lesion ◽  
Abdominal Mass ◽  
Surgical Excision ◽  
Cystic Neoplasm ◽  
Mesenchymal Hamartoma ◽  
Transplantation Surgery ◽  
Clinical Center ◽  
The Right

Introduction. Mesenchymal hamartoma of the liver is a benign lesion presenting as an enlarging abdominal mass in children less than 2 years of age. Fewer than 5% cases are present in individuals over 5 years of age, and this lesion is extremely rare in adults. It may affect the left or the right lobe of liver as a cystic or solid mass or both components may be present. The pathogenesis remains incompletely understood, but these lesions have generally been considered to represent a development abnormality in the bile duct plate formation. Case Report. In this report, we present a case of a 44-year-old man who was surgically treated at the Department of Abdominal, Endocrine and Transplantation Surgery of the Clinical Center of Vojvodina due to cystic lesion in the liver segment IV that had been verified by computed tomography imaging diagnostics. The patient was sent from a smaller health center with the diagnosis of echinococcosis. After the adequate preparation of the patient, surgical excision of the liver cystic lesion was done. Once a thorough histological examination had been performed, the diagnosis of mesenchymal hamartoma was made. Conclusion. Mesenchymal hamartoma of the liver is a benign tumor resulting from abnormal, intra-uterine development of bile ducts and has a delayed clinical manifestation, thus this lesion appears to be related to the processes of maturation. It is potentially premalignant lesion presenting as a solid and/or cystic neoplasm. Symptoms, laboratory results and radiographic imaging are nonspecific and inconclusive, so surgical excision of the whole lesion is the imperative for the definitive diagnosis.

Structural and vascular features in cavitary congenital optic disc anomaly associated with metaphyseal acroscyphodysplasia

2021 ◽  
pp. 112067212199574
Author(s):  
Federica Fossataro ◽  
Luca D’Andrea ◽  
Gilda Cennamo
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Disc ◽  
Systemic Disease ◽  
Wide Field ◽  
Fundus Examination ◽  
Optical Coherence ◽  
Optic Disc Coloboma ◽  
Retinal Epithelium ◽  
The Right ◽  
Optic Disc Anomaly

Purpose: To evaluate the radial peripapillary vascular plexus of a cavitary congenital optic disc anomaly in a young patient with recessive autosomal metaphyseal acroscyphodysplasia using optical coherence tomography angiography (OCTA). Methods: Observational case report. Results: A 17-year-old man, with diagnosis of metaphyseal acroscyphodysplasia was referred to Eye Clinic for fundus examination and multimodal imaging for retinal epithelium hypertrophy in the right eye. Clinical examination showed cup-shaped metaphyses, short stature, hyperthelorism, and telecanthus. An optic disc coloboma was detected in the right eye on fundus examination. Wide field en-face Optical Coherence Tomography (OCT) showed a hyporeflective area corresponding to the right optic disc coloboma. At OCTA examination, the whole papillary region revealed a rarefaction of the vascular network, while the ganglion cell complex’s and retinal fiber layers’ parameters were normal in both eyes. Conclusion: The presence of coloboma disc congenital defect linked to embryological abnormalities during the development process could pave the way for a wider understanding of the pathogenesis of metaphyseal acroscyphodysplasia by increasingly framing it as a systemic disease.

Aural metastasis from a nasal malignant melanoma: case report with literature review

2011 ◽  
Vol 125 (12) ◽  
pp. 1290-1293 ◽  
Author(s):  
I Khan ◽  
S Mohamad ◽  
M Shakeel ◽  
M J Jaramillo
Keyword(s):  
Case Report ◽  
Malignant Melanoma ◽  
Literature Review ◽  
Multidisciplinary Team ◽  
Resection Margins ◽  
Rare Tumour ◽  
Temporal Bone Resection ◽  
Team Decision ◽  
The Right ◽  
Optimum Management

AbstractObjective:To raise awareness of nasal malignant melanoma, a rare tumour, and to highlight the difficulty associated with its optimum management.Method:Case report and literature review.Case report:A 71-year-old, Caucasian man was diagnosed with malignant melanoma in the right nasal cavity, after presenting with right-sided epistaxis. He underwent endoscopic medial maxillectomy; histological analysis confirmed that the resection margins were clear. However, within six months he re-presented with a metastatic deposit of malignant melanoma in his right external auditory canal, for which he underwent right temporal bone resection. There was no evidence of distant metastasis on radiological studies. Unfortunately, within a month the tumour recurred in the right nasopharynx. A multidisciplinary team decision was made to offer the patient palliative chemoradiotherapy.Conclusion:Mucosal malignant melanoma of the nose is very rare, and aural metastasis from this primary site has not previously been reported. Optimum management must involve a multidisciplinary team.

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