scholarly journals Upper Esophageal Schwannoma: Rare Differential Diagnosis of Dysphagia

2020 ◽  
Vol 4 (1) ◽  
pp. 84-87
Author(s):  
Bigyan Acharya ◽  
Binay Thakur ◽  
Mukti Devkota ◽  
Greta Pandey ◽  
Anup Shrestha ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Differential Diagnosis ◽  
Histopathological Examination ◽  
External Compression ◽  
Rare Differential Diagnosis ◽  
Mucosal Mass ◽  
Vats Esophagectomy ◽  
Esophageal Schwannoma

Esophageal schwannomas are rare primary sub mucosal tumors, 45 cases have been reported so far. We  herein report the 46th case of an esophageal schwannoma from Nepal. A 60-year-old woman presented with progressivedysphagia. Oesophago-Gastro-Duodenoscopy (OGD) showed a sub mucosal mass with mucosal puckering in the upper esophagus; Computed tomography (CT) of the chest showed an upper esophageal mass of size 8x7x6cm3compressing the trachea. Bronchoscopy showed external compression of the mid trachea. The patient under went three incision VATS esophagectomy. Histopathological examination and immunohistochemical (IHC) staining confirmed the diagnosis of schwannoma.

scholarly journals Extragonadal Germ-Cell Tumor: A Rare Differential Diagnosis of a Cervical Lump in a Young Man

2002 ◽  
Vol 81 (8) ◽  
pp. 580-582
Author(s):  
Britta Eickhoff ◽  
Michael Jaehne ◽  
Florian Langer
Keyword(s):  
Computed Tomography ◽  
Differential Diagnosis ◽  
Case Report ◽  
Germ Cell ◽  
Germ Cell Tumor ◽  
Clinical Situation ◽  
Cell Tumor ◽  
Extragonadal Germ Cell Tumor ◽  
Rare Differential Diagnosis ◽  
Cervical Swelling

In this case report, we discuss the potential diagnostic difficulty of identifying the cause or origin of a cervical swelling, a clinical situation often encountered in otolaryngology patients. A 30-year-old man came to us with a painless left cervical lump that he had noticed 8 weeks earlier. A series of examinations—including various biopsies, computed tomography, and extensive staging procedures—could not establish the diagnosis. We eventually identified the mass as an extragonadal germ-cell tumor. The diagnosis was established only after additional serologic testing and detection of tumor markers specific for extragonadal germ-cell tumor.

scholarly journals Differential diagnosis for a mandibular mass – a rare case of an odontoameloblastoma in a red deer (Cervus elaphus elaphus)

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Svenja Hartung ◽  
Kernt Köhler ◽  
Christiane Herden ◽  
Manfred Henrich
Keyword(s):  
Differential Diagnosis ◽  
Cervus Elaphus ◽  
Bacterial Infections ◽  
Red Deer ◽  
Histopathological Examination ◽  
Odontogenic Tumors ◽  
Pathological Examination ◽  
Rare Differential Diagnosis ◽  
Inflammatory Processes ◽  
Free Ranging

Abstract Background Mandibular masses caused by inflammatory processes due to bacterial infections, most common with Actinomyces bovis, are well known in herbivors. This case represents a rare differential diagnosis to common inflammatory processes which cannot be distinguished from neoplasia without detailed histopathological examination. Case presentation A large unilateral mandibular mass of a free-ranging female adult red deer (Cervus elaphus elaphus) was submitted for pathological examination. The animal had been shot due to its poor body condition. Grossly, the mandibular mass showed gingival ulceration and necrosis. Histologically, irregular strands and islands of odontogenic epithelial cells and a matrix of dentin and osteoid-like material were found, leading to the diagnosis of an odontogenic tumor. Considering the animal’s age the tumor was classified as odontoameloblastoma with secondary chronic purulent osteomyelitis. Conclusions Odontogenic tumors are rare in domestic and wildlife species and so far have not been reported in red deer. In addition to the more common inflammatory processes of the mandibula and other neoplastic diseases of the oral cavity, odontogenic tumors represent a rare differential diagnosis that must be kept in mind especially when masked by inflammatory lesions.

scholarly journals Primary Heterotopic Meningioma of Nasal Cavity: Case Report and Literature Review

2020 ◽  
pp. 014556132097486
Author(s):  
Xianwen Hu ◽  
Maoyan Jiang ◽  
Zelong Feng ◽  
Juan Wang ◽  
Pan Wang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Differential Diagnosis ◽  
Nasal Cavity ◽  
Histopathological Examination ◽  
Final Diagnosis ◽  
Ectopic Meningioma ◽  
Pathological Type ◽  
Immunohistochemistry Analysis ◽  
The Right ◽  
Histopathological Subtype

Primary heterotopic meningiomas are lesions that are not associated with a cranial nerve foramen, vertebral canal, or intracranial structure. The most common histopathological subtype is meningeal epithelioma. In clinical practice, primary heterotopic nasal meningioma occurs relatively rarely, and its most common pathological type is psammomatous meningioma, whereas nasal fibrous meningioma is infrequent. In our case, a 31-year-old male patient was admitted to the hospital with “progressive nasal obstruction on the right side for half a year.” Computed tomography examination of the paranasal sinuses revealed a polyploid mass in the right nasal cavity. The patient underwent surgical resection of the mass under nasal endoscopy. Histopathological examination confirmed that the mass was an ectopic meningioma of the nasal cavity. The patient was regularly followed up for 2 years without recurrence of the tumor. Primary heterotopic fibrous meningioma of the nasal cavity is clinically rare but should be considered as a differential diagnosis for hemangioma of the nasal cavity, inverted papilloma, and nasal polyp. The final diagnosis is based on pathology and immunohistochemistry analysis results.

scholarly journals Intraperitoneal liposarcoma: a rare presentation

2021 ◽  
Vol 8 (4) ◽  
pp. 1356
Author(s):  
Gokul Rajendran ◽  
Saichaithanya Kapuluru ◽  
Durganna Thimmappa
Keyword(s):  
Differential Diagnosis ◽  
Histopathological Examination ◽  
Abdominal Mass ◽  
Rare Occurrence ◽  
Provisional Diagnosis ◽  
Rare Presentation ◽  
Rare Differential Diagnosis ◽  
Well Differentiated ◽  
Greater Curvature ◽  
Sigmoid Mesocolon

Liposarcoma are frequently seen in the retroperitoneum. It is of four types pathologically: Well-differentiated, dedifferentiated, myxoid and pleomorphic. Well-differentiated is the most common type. Dedifferentiated has the worst prognosis. Reports of Liposarcoma arising from the intraperitoneal sites such as stomach, omentum, mesentery and sigmoid mesocolon are rare. A 47 year old gentleman presented with pain in abdomen and abdominal distention, had a provisional diagnosis of GIST, intra-peritoneal liposarcoma. Imaging revealed a well-defined encapsulated abdominal mass indicative of liposarcoma with fibrous differentiation/fibro-lipoma. On surgery a well encapsulated mass was excised completely arising from the greater curvature of stomach. The mass on histopathological examination indicated features suggestive of liposarcoma (well-differentiated) with IHC markers positive for S100, CDK4 and MDM2. A diagnosis of intraperitoneal liposarcoma form greater curvature of stomach was made. This was an exceedingly rare presentation of liposarcoma arising from the greater curvature of stomach with differential diagnosis of GIST which was ruled out with histopathological features and negative CD117 and CD34. Thus to conclude liposarcoma being quite common retroperitoneal tumor, has an exceedingly rare occurrence from intraperitoneal sites and should be taken as an exceedingly rare differential diagnosis for mass per abdomen.

scholarly journals Scopolamine fatal outcome in an inmate after buscopan® smoking

2021 ◽  
Author(s):  
Sabina Strano-Rossi ◽  
Serena Mestria ◽  
Giorgio Bolino ◽  
Matteo Polacco ◽  
Simone Grassi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Drug Abuse ◽  
Muscarinic Receptors ◽  
Histopathological Examination ◽  
Fatal Outcome ◽  
Post Mortem ◽  
Butyl Bromide ◽  
Cannabis Abuse ◽  
Toxic Concentration ◽  
History Of

AbstractScopolamine is an alkaloid which acts as competitive antagonists to acetylcholine at central and peripheral muscarinic receptors. We report the case of a 41-year-old male convict with a 27-year history of cannabis abuse who suddenly died in the bed of his cell after having smoked buscopan® tablets. Since both abuse of substances and recent physical assaults had been reported, we opted for a comprehensive approach (post-mortem computed tomography CT (PMCT), full forensic autopsy, and toxicology testing) to determine which was the cause of the death. Virtopsy found significant cerebral edema and lungs edema that were confirmed at the autopsy and at the histopathological examination. Scopolamine was detected in peripheral blood at the toxic concentration of 14 ng/mL in blood and at 263 ng/mL in urine, and scopolamine butyl bromide at 17 ng/mL in blood and 90 ng/mL in urine. Quetiapine, mirtazapine, lorazepam, diazepam, and metabolites and valproate were also detected (at therapeutic concentrations). Inmates, especially when they have a history of drug abuse, are at risk to use any substance they can find for recreational purposes. In prisons, active surveillance on the management and assumption of prescribed drugs could avoid fatal acute intoxication.

scholarly journals Giant Fibrovascular Polyp as an Unusual Cause of Globus Pharyngeus

2021 ◽  
pp. 014556132110039
Author(s):  
Jelena Sotirović ◽  
Ljubomir Pavićević ◽  
Stanko Petrović ◽  
Saša Ristić ◽  
Aleksandar Perić
Keyword(s):  
Differential Diagnosis ◽  
Asymptomatic Patient ◽  
Histopathological Examination ◽  
Complete Resection ◽  
Airway Compromise ◽  
Endoscopic Removal ◽  
Globus Sensation ◽  
Fibrovascular Polyp ◽  
History Of ◽  
Fatal Complications

Differential diagnosis of globus sensation in an otherwise asymptomatic patient should include hypopharyngeal fibrovascular polyp to avoid potentially fatal complications like airway compromise following regurgitation. We present a case of a 74-year-old man with a 13-cm long hypopharyngeal fibrovascular polyp with 9 months history of globus sensation. A narrow stalk of the giant polyp allowed endoscopic removal and complete resection with the CO2 laser. Histopathological examination was conclusive for the fibrovascular polyp.

Chronic mesenteric ischaemia presenting as possible large bowl malignancy: an easily overlooked differential diagnosis

2021 ◽  
Vol 14 (3) ◽  
pp. e240202
Author(s):  
Benjamin McDonald
Keyword(s):  
Computed Tomography ◽  
Emergency Department ◽  
Weight Loss ◽  
Differential Diagnosis ◽  
Damage Control ◽  
Damage Control Surgery ◽  
Mesenteric Ischaemia ◽  
Abdominal Symptoms ◽  
Chronic Mesenteric Ischaemia ◽  
Descending Colon

An 80-year-old woman presented to a regional emergency department with postprandial pain, weight loss and diarrhoea for 2 months and a Computed Tomography (CT) report suggestive of descending colon malignancy. Subsequent investigations revealed the patient to have chronic mesenteric ischaemia (CMI) with associated bowel changes. She developed an acute-on-chronic ischaemia that required emergency transfer, damage control surgery and revascularisation. While the patient survived, this case highlights the importance of considering CMI in elderly patients with vague abdominal symptoms and early intervention to avoid potentially catastrophic outcomes.

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