scholarly journals Recurrent Pyogenic Cholangitis as an Unusual Indication for Liver Transplantation in a Center of a Western Country

2020 ◽  
pp. 1-5
Author(s):  
Concepción Gómez-Gavara ◽  
Concepción Gómez-Gavara ◽  
Lluís Castells ◽  
Isabel Campos-Varela ◽  
Berta Pares Bofill ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Liver Transplantation ◽  
Antibiotic Therapy ◽  
Biliary Drainage ◽  
Chronic Infection ◽  
Therapeutic Approach ◽  
Western Country ◽  
Chinese Patients ◽  
Biliary Stones ◽  
Recurrent Pyogenic Cholangitis

Recurrent pyogenic cholangitis is a chronic infection characterized by intrahepatic biliary stones and strictures. Escherichia coli is the commonest infecting organism. This disease is very common in East Asia but infrequent in Western countries, and few reports have been published in European series. The therapeutic approach for hepatolithiasis is highly individual and includes antibiotic therapy, endoscopic and percutaneous biliary drainage with stone removal and dilation of strictures, surgical resection of affected liver segments and liver transplantation. We report two cases of RCP in Chinese patients treated with liver transplantation at our center out of the 34 published in the literature.

scholarly journals Serotypes of Escherichia coli isolated from patients with recurrent pyogenic cholangitis

1982 ◽  
Vol 88 (3) ◽  
pp. 513-517 ◽  
Author(s):  
W. T. Wong ◽  
K. A. Bettelheim ◽  
F. C. Y. Cheng ◽  
G. B. Ong
Keyword(s):  
Escherichia Coli ◽  
Hong Kong ◽  
Chinese Population ◽  
Hong Kong Chinese ◽  
Chinese Patients ◽  
Recurrent Pyogenic Cholangitis

SummaryStrains of Escherichia coli were isolated from laparotomy specimens from Chinese patients with recurrent pyogenic cholangitis in Hong Kong. A large variety of serotypes were found. Several sites were sampled in each patient. While only one serotype was normally isolated from one site, different sites often yielded different serotypes in the same patient. Generally the ‘O’ types found did not correspond to those found in the faeces of the Hong Kong Chinese population.

Emergency percutaneous biliary drainage in patients post liver transplantation

2003 ◽  
Vol -1 (1) ◽  
pp. 1-1
Author(s):  
H. Abujudeh ◽  
M. Margolina ◽  
R. Aronov ◽  
S. Baker
Keyword(s):  
Liver Transplantation ◽  
Biliary Drainage ◽  
Percutaneous Biliary Drainage

scholarly journals Newer molecules and new hopes in the management of chronic hepatitis C

JMS SKIMS ◽  
2010 ◽  
Vol 13 (2) ◽  
pp. 39-40
Author(s):  
Showkat Ali Zargar
Keyword(s):  
Hepatocellular Carcinoma ◽  
Immune Response ◽  
Liver Transplantation ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Chronic Infection ◽  
Antiviral Therapies ◽  
Chronic Hcv Infection ◽  
Chronic Hcv

Chronic hepatitis C is highly prevalent with prevalence rate of around 3% involving about 180 million people worldwide, despite major advances in its understanding of viral 1 pathogenesis and significant evolution in antiviral therapies. Most of the patients develop chronic infection because the virus evades the host immune response in majority of patients. Chronic HCV infection can lead to cirrhosis and hepatocellular carcinoma. Complications of HCV-related cirrhosis are the leading indication for liver transplantation in United States and Europe...... J Med Sci 2010;13(2): 39-40.

scholarly journals EFFICACY OF SODIUM NUCLEINATE INCOMPLEX TREATMENT OFPATIENTS WITH RECURRENT PYELONEPHRITIS

2014 ◽  
pp. 22-28
Author(s):  
N. Stepanova ◽  
V. Driyanska ◽  
V. Kruglikov ◽  
L. Lebid ◽  
O. Kornilina ◽  
...  
Keyword(s):  
Clinical Study ◽  
Antibiotic Therapy ◽  
Mucosal Immunity ◽  
Phagocytic Activity ◽  
Therapeutic Approach ◽  
Urogenital Tract ◽  
Control Group ◽  
Genitourinary System ◽  
Randomized Clinical Study ◽  
Blood Cytokines

The aim of our study was to determine the effectiveness of Sodium nucleinate in treatment of patients with recurrent pyelonephritis. Material and methods. This clinical study is a prospective, open, controlled, randomized clinical study. Two types of therapies were evaluated in parallel groups. 98patients with recurrent pyelonephritis were examined in the dynamics of treatment. We investigated the state of the genitourinary system microbiota, mucosal immunity performance of the urogenital tract and contents of blood cytokines. After the examination the patients were divided by the applied therapeutic approach. The first group of the women (n=55) received antibiotic therapy and Sodium nucleinate 0.25 g 4 times per day for 2 weeks. The second group of the women (n=43) received only antibiotics. Results. The frequency of eradication of U. urealyticum (including in association with M. hominis) was significantly higher in patients of the first group. We have identified a significantly higher phagocytic activity and a phagocytosis intensity of neutrophils in samples from the vagina in women of the first group (46 [28-49] vs 17 [13-27.5] p = 0.002 and 3.19 [2.34-4.9] against 2.8 [1.23-3.6] p=0.02, respectively).The study of mucosal immunity has demonstrated a significant decrease the content of lactoferrin and increasing sIg A in the urine of patients of group (6.85 [0.2-80] vs 0 [0-0.4] ng/ml, p=0.01 and 0.42 [0-0,7] vs. 3.2 [0-3,7]g/ml, p=0.04, respectively).In addition, the use of Sodium nucleinate promoted to a significant reduction of high levels of all investigated cytokines: IL-4 (p=0.003), IL-17 (p=0.005), NGAL (p=0.02), TNF-$ (p=0.02) and MCP-1 (p=0.03). In the control group was achieved just the reduction in levels of IL-4 (p=0.007) and IL-17 (p=0.04). Conclusions. Thus, the application of the proposed therapies can improve the effectiveness of the treatment of patients with recurrent pyelonephritis by normalization of mucosal immunity of the genitourinary system and the cytokine profile. We believe that the traditional antibiotic therapy ofpatients with recurrent pyelonephritis advisable to supplement of Sodium nucleinate at a dose of 0.25g 4 times / day for 2 weeks.

Bone and joint infections in children

2013 ◽  
pp. 753-763
Author(s):  
Alasdair Munro ◽  
Julia Clark ◽  
Saul N. Faust
Keyword(s):  
Surgical Treatment ◽  
Antibiotic Therapy ◽  
Chronic Infection ◽  
Laboratory Tests ◽  
Oral Treatment ◽  
Timely Initiation ◽  
Joint Infections ◽  
Bone And Joint Infections ◽  
Wide Range ◽  
Direct Inoculation

Bone and joint infections in children are uncommon, but they affect all ages and there is a wide range of disease. The mode of infection may be haematogenous or by direct inoculation from a wound. The child may present acutely unwell or with a chronic infection. Clinical features include fever, reluctance to move the affected limb, pain, and swelling. Laboratory tests and medical imaging are used to confirm diagnosis. Medical treatment is with initial intravenous antibiotic therapy, usually followed by oral treatment. Surgical treatment may be necessary if abscess or joint collection is present. In general prognosis is good with timely initiation of treatment, although complications such as pathological fracture are occasionally seen.

scholarly journals Predictive factors for biliary stones after donor brain dead liver transplantation

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S831-S832
Author(s):  
U. Maggi ◽  
G. Paone ◽  
A. Chierici ◽  
G. Fornoni ◽  
D. Conte ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Predictive Factors ◽  
Biliary Stones ◽  
Brain Dead

scholarly journals Clear mortality gap caused by graft macrosteatosis in Chinese patients after cadaveric liver transplantation

2020 ◽  
Vol 9 (6) ◽  
pp. 739-758
Author(s):  
Zhengtao Liu ◽  
Wenchao Wang ◽  
Li Zhuang ◽  
Jingfeng Liu ◽  
Shuping Que ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Chinese Patients

scholarly journals Routine antibiotic therapy in dogs increases the detection of antimicrobial-resistant faecal Escherichia coli

2018 ◽  
Author(s):  
Vanessa M Schmidt ◽  
Gina Pinchbeck ◽  
K Marie McIntyre ◽  
Tim Nuttall ◽  
Neil McEwan ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Antibiotic Therapy
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