scholarly journals Base of Tongue Non-Hodgkin’s Lymphoma: Difficult Intubation

2021 ◽  
pp. 1-4
Author(s):  
Hazem Kafrouni ◽  
Joui Makhoul ◽  
Hazem Kafrouni

Primary Non-Hodgkin’s Lymphoma (NHL) of the tongue is a very rare tumor most commonly affecting elderly patients causing upper airway obstruction and anticipated difficult intubations with space occupying lesions that prevent tongue displacement and hence, scarce space for laryngoscopy. A 78-year-old man presented with progressive stridor and dyspnea. Oral examinations revealed tongue asymmetry and friable ulcerative lesions. During induction of anaesthesia in a scheduled partial glossectomy, difficult nasotracheal intubation was encountered despite using the Glidescope. Laryngeal landmarks could not be identified but successful nasotracheal intubation by hand-assisted and magill forceps manipulation of the endotracheal tube direction under video laryngoscopy. Failed intubation should always be considered in the management of base of tongue tumors. Pre-operative assessment and planning to secure the airway in patients presenting with base of tongue tumors decreases morbidity and mortality, especially when an emergency plan is prepared. No single airway management technique can be used for every patient. Further research is required for guiding the choice of airway management in such patients.

2014 ◽  
Vol 5 (3) ◽  
pp. 155-157 ◽  
Author(s):  
Paramjeet Kaur ◽  
Anil Khurana ◽  
Ashok K Chauhan ◽  
Gajender Singh ◽  
Sant Parkash Kataria

ABSTRACT The occurrence of two malignant lesions synchronously of different histology at same anatomical region of the patient is a rare presentation. Coexistence of squamous cell carcinoma and malignant lymphoma of head and neck region synchronously is uncommon. Here is a report of case of 65 years old female patient who presented with a mass in right side of neck and in midline of neck of 2 months duration. After thorough work up, the patient was diagnosed as having squamous cell carcinoma of right side base of tongue and non-Hodgkin's lymphoma (NHL) of thyroid. The patient was treated with radiotherapy and chemotherapy. How to cite this article Kaur P, Khurana A, Chauhan AK, Singh G, Kataria SP. Non-Hodgkin's Lymphoma of Thyroid Synchronously with Squamous Cell Carcinoma Base of Tongue: A Rare Coincidence and Treatment Strategy. Int J Head Neck Surg 2014;5(3):155-157.


1993 ◽  
Vol 70 (04) ◽  
pp. 568-572 ◽  
Author(s):  
Roberto Stasi ◽  
Elisa Stipa ◽  
Mario Masi ◽  
Felicia Oliva ◽  
Alessandro Sciarra ◽  
...  

SummaryThis study was designed to explore the prevalence and clinical significance of elevated antiphospholipid antibodies (APA) titres in patients affected by acute myeloid leukemia (AML) and highgrade non-Hodgkin’s lymphoma (NHL). We also analyzed possible correlations with circulating levels of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), and the soluble form of the receptor for interleukin-2 (sIL-2r). Nineteen patients with de novo AML and 14 patients with newly-diagnosed NHL were investigated. Tests for APA included the measurement of anticardiolipin antibodies (ACA) with a solid-phase immunoassay, and the detection of the lupus-like anticoagulant (LA) activity. Five patients with AML (26.3%) and 5 patients with NHL (35.7%) presented elevated APA at diagnosis, as compared to 3 of 174 persons of the control group (p <0.0001). APA titres became normal in all patients responding to treatment, whereas nonresponders retained elevated levels. In addition, 6 patients (4 with AML and 2 with NHL), who had normal APA at diagnosis and were either refractory to treatment or in relapse, subsequently developed LA and/or ACA positivity. At presentation, the mean levels of IgG- and IgM-ACA in patients were not significantly different from Controls, and concordance between ACA and LA results reached just 30%. With regard to the clinical course, we were not able to detect any statistically significant difference between patients with normal and elevated APA. Pretreatment concentrations of IL-6 and TNF-alpha in AML, and sIL-2r in NHL were found significantly elevated compared to Controls (p = 0.003, p = 0.009 and p = 0.024 respectively). In addition, the levels of these cytokines correlated with IgG-ACA at the different times of laboratory investigations. These results demonstrate that APA may have a role as markers of disease activity and progression in some haematological malignancies.


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