scholarly journals Comparison of the Clinical Status and Immunological Parameters of Patients with Autoimmune Thyroiditis with and without Type 1 Diabetes Mellitus

Doctor Ru ◽  
2020 ◽  
Vol 19 (2) ◽  
pp. 45-50
Author(s):  
Ya.V. Girsh ◽  
◽  
L.A. Bolotskaya ◽  
A.A. Tarlyun ◽  
◽  
...  
2019 ◽  
Vol 13 (1) ◽  
pp. 608-611
Author(s):  
Natalia Vallianou ◽  
Theodora Stratigou ◽  
Stavroula Koutroumpi ◽  
Barbara Vlassopoulou ◽  
Stylianos Tsagarakis ◽  
...  

2019 ◽  
Vol 123 ◽  
pp. 68-73 ◽  
Author(s):  
Magdalena Hoffmann ◽  
Jolanta Neubauer-Geryk ◽  
Melanie Wielicka ◽  
Magdalena Kowaleczko ◽  
Małgorzata Myśliwiec ◽  
...  

2019 ◽  
Vol 14 (4) ◽  
pp. 206-209
Author(s):  
Margarita S. Mikhina ◽  
Ekaterina A. Troshina ◽  
Tatiana V. Nikonova

Diabetes mellitus and primary hypothyroidism, in the outcome of chronic autoimmune thyroiditis, the two most common diseases in endocrinology and the practicing doctor are important not to forget about the possible association of these pathologies. This applies to patients with diabetes mellitus, both 1 and 2 types. However, the combination of these two pathologies is more common in type 1 diabetes, which is due to the autoimmune nature of these diseases. A clinical case of a patient with type 1 diabetes mellitus, which is on pump insulin therapy, is presented, which, in the background of previously selected therapy, during the last 2 months, episodes of hypoglycemia increased. In the course of the survey, primary subclinical hypothyroidism was identified, in the outcome of chronic autoimmune thyroiditis. Against the background of the achievement of euthyroidism, it was possible to achieve compensation of carbohydrate metabolism without correction of previously selected insulin therapy. The high incidence of thyroid dysfunction in patients with diabetes mellitus, and as a consequence, the deterioration in the compensation of carbohydrate metabolism, requires a systematic screening of thyroid disorders in the presence of diabetes mellitus.


2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Mariam Balakhadze ◽  
Elene Giorgadze ◽  
Marina Lomidze

Aim. Chronic autoimmune thyroiditis and type 1 diabetes mellitus are organ-specific autoimmune diseases. There is large evidence that autoimmunity against the thyroid gland in patients with type 1 diabetes mellitus is increased, but little is known about anti-islet cell autoimmune status in patients with chronic autoimmune thyroiditis. We evaluated the concentration of antibodies against glutamic acid decarboxylase (GAD) which are widely used as a diagnostic and predictive tool for type 1 diabetes mellitus, in school-aged Georgian children with chronic autoimmune thyroiditis.Methods. The frequency of anti-GAD antibodies was measured in Georgian school-aged children with chronic autoimmune thyroiditis and compared to healthy age and sex matched controls.Results. Of the 41 patients with chronic autoimmune thyroiditis 4 (9.8%) were positive for GAD antibodies. The frequency of GAD positivity in the chronic autoimmune thyroiditis group was significantly higher than in the control subjects (P=0.036).Conclusion. In the study we found that the frequency of GAD antibody positivity in autoimmune thyroiditis patients was significantly higher (9.8%,P=0.036) than in the control group. Our findings support the concept that patients with autoimmune thyroid disease may develop type 1 diabetes mellitus in future life.


2004 ◽  
Vol 24 (2) ◽  
pp. 169-171 ◽  
Author(s):  
Josko Bulum ◽  
Nikica Car ◽  
Lea Smircic-Duvnjak ◽  
Sonja Gracin ◽  
Zeljko Metelko

Sign in / Sign up

Export Citation Format

Share Document