Choroid plexus papilloma in a girl with hypomelanosis of Ito

2012 ◽  
Vol 10 (3) ◽  
pp. 182-185 ◽  
Author(s):  
Ryoma Morigaki ◽  
Kyong-Hon Pooh ◽  
Kenji Shouno ◽  
Hidekazu Taniguchi ◽  
Shouichi Endo ◽  
...  

The authors report a case of choroid plexus papilloma in a girl with hypomelanosis of Ito, and they review the literature in brief. Hypomelanosis of Ito is a rare neurocutaneous syndrome characterized by cutaneous hypopigmented whorls, streaks, and patches along lines of Blaschko. Most patients exhibit CNS manifestations, including psychomotor retardation, seizures, hypotonia, and ataxia. A 6-year-old girl with hypomelanosis of Ito was referred to the authors' hospital with bilateral tumors in the lateral ventricles. The right lateral ventricle tumor was surgically removed. Immunohistochemical investigations revealed the tumor to be a choroid plexus papilloma (WHO Grade I). A chromosomal investigation revealed that the tumor tissue demonstrated a large loss of heterozygosity at chromosome 10. The case reported here serves as a reminder that de novo brain tumors may arise in patients with chromosomal mosaicism.

2009 ◽  
Vol 57 (3) ◽  
pp. 389-397 ◽  
Author(s):  
Luciano Espino ◽  
Maruska Suarez ◽  
German Santamarina ◽  
Mónica Vila ◽  
Natalia Miño ◽  
...  

A 7-year-old spayed female English Cocker Spaniel was examined because of a 1-week history of lethargy, stumbling over objects and circling, and the presence of two tonic-clonic generalised seizures two days before presentation. The neurological signs suggested a lesion involving the right forebrain. Computed tomography revealed the presence of two intracranial masses, one located inside the right lateral ventricle and the other located in the right frontal lobe attached to the falx cerebri. Because of the poor prognosis, the owner refused to continue with the therapy and the dog was euthanised. On postmortem examination one mass was diagnosed histologically as a meningioma and the other as a papilloma of the choroid plexus. Information in the veterinary literature on multiple malignancies affecting the central nervous system is very limited. To the best of the authors’ knowledge, the association of meningioma and choroid plexus papilloma has never been reported either in the human or in the veterinary medical literature.


Neurosurgery ◽  
1986 ◽  
Vol 18 (6) ◽  
pp. 781-783 ◽  
Author(s):  
Jorge Salazar ◽  
Jesùs Vaquero ◽  
Ignacio F. Aranda ◽  
Josefa Menèndez ◽  
Dolores M. Jimenez ◽  
...  

Abstract The authors report the successful total removal of a rare intracranial tumor in the right lateral ventricle of a 15-year-old girl with epileptic seizures. Histopathological examination showed a benign tumor formed by mature cartilage and choroid plexus papilloma. From our review of the literature, a mixed tumor with these histological features has not been reported previously in this location. The diagnosis, surgical approach, etiology, and prognosis of this lesion are discussed.


2019 ◽  
Vol 46 (2) ◽  
pp. 61-65
Author(s):  
Mohammad Hossain ◽  
Nazmin Ahmed ◽  
Narendra Shalike ◽  
Md Rokibul Islam ◽  
Soumen Samadder ◽  
...  

Choroid plexus tumors are rare intracranial tumors which account for 0.4-0.6% of all brain tumors. Choroid plexus tumors represent a spectrum of neoplasms derived from papillary epithelium of normal choroid plexus, including well-differentiated papilloma (WHO grade I), intermediate form as atypical Choroid Plexus Papilloma (WHO grade II) and highly aggressive choroid plexus carcinomas (WHO grade III). Though rare, it is responsible for the communicating hydrocephalus in children due to overproduction of cerebrospinal fluid. Due to advances in molecular biology and better understanding of the tumorigenesis of choroid plexus papilloma, now it is established that several genetic syndromes and central nervous sytem abnormalities are associated with this tumor. Here, we reported a case of a 10 months old child who presented with sudden deterioration of consciousness level and after thorough evaluation, diagnosed as a case of Choroid Plexus Papilloma with Dandy Walker Variant. Till date, this is the first reported case of the association/ co-existence of such two conditions which needs further evaluation. Bangladesh Med J. 2017 May; 46 (2): 61-65


2021 ◽  
Vol 20 (4) ◽  
pp. 33-41
Author(s):  
A. F. Valiakhmetova ◽  
L. I. Papusha ◽  
A. V. Sanakoeva ◽  
L. V. Shishkina ◽  
O. I. Budanov ◽  
...  

Choroid plexus tumors (CPTs) are rare intraventricular tumors, accounting 2–5% of brain tumors in children. Choroid plexus papilloma (CPP) classified by the World Health Organization (WHO) on the basis of histological criteria as benign tumor (WHO grade I), CPPs accounts for 10–20% of brain tumors during the first year of life, the median age of patients with CPP at the time of diagnosis – 3.5 years. Atypical choroid plexus papilloma (APP) is an intermediate (WHO grade II) tumor which was officially included in the WHO classification in 2007. Median age 0,63 years. In this work, for the first time in the Russian literature, we present the outcomes of CPP and APP therapy in a large cohort of patients. The study was approved by the Independent Ethics Committee and the Scientific Council of the D. Rogachev NMRCPHOI. In our study from January 1, 2009 to December 31, 2019, 83 CPP and 37 APP were histologically verified. For all patients, surgical removal of the tumor was the first stage of treatment. In 79 (95.2%) patients with CPP and in 32 (86.5%) children with APP, radical resection was performed at the first stage. In 73.5% of children with CPP and 62.2% of children with APP there was no intra- and postoperative complications. In both CPP and APP, the 5-year EFS in patients with complete resection was statistically significantly higher compared to subtotal tumor resection (100% and 33 ± 27% in CPP, 94 ± 4% and 25 ± 22% for APP) (p < 0.001). Chemoradiation therapy was given to 1 patient with CPP, 4 patients with APP with tumor recurrence/progression. 


1997 ◽  
Vol 5 (2) ◽  
pp. 61-68 ◽  
Author(s):  
Elaine R. Levy ◽  
Sharon W. Horsley ◽  
Andrew Miller ◽  
Elisabeth Steichen-Gersdorf ◽  
Anthony P. Monaco ◽  
...  

2014 ◽  
Vol 36 (v1supplement) ◽  
pp. 1
Author(s):  
Lee A. Tan ◽  
Ricardo B. Fontes ◽  
Richard W. Byrne

Choroid plexus papillomas (CPP) are uncommon benign brain tumors that usually arise in the fourth ventricle in adults and lateral ventricles in children. Extraventricular CPPs are rare and can be found primarily in the cerebellopontine angle (CPA). We present a case of primary extraventricular CPP in the right CPA successfully resected with retrosigmoid approach. Detailed surgical techniques of retrosigmoid craniotomy and tumor dissection are presented in high definition video with narration.The video can be found here: http://youtu.be/6591en3nWlY.


1971 ◽  
Vol 8 (1) ◽  
pp. 91-95 ◽  
Author(s):  
H. J. Kurtz ◽  
Griselda F. Hanlon

A 6-year-old female Cocker Spaniel with a choroid plexus papilloma had clinical signs of disease of the central nervous system for 1 month. The neoplasm originated from the right choroid plexus of the fourth ventricle and had displaced contiguous parts of the medulla oblongata and cerebellum. It was well differentiated and was composed of papillae arranged in an arboriform pattern. The papillae were lined by a single layer of non ciliated epithelium.


2009 ◽  
Vol 45 (2) ◽  
pp. 97-101 ◽  
Author(s):  
Yvonne van Zeeland ◽  
Nico Schoemaker ◽  
Maartje Passon-Vastenburg ◽  
Marja Kik

A 6-year-old, castrated male ferret (Mustela putorius furo) was presented with progressive neurological signs consisting of a right-sided head tilt and ataxia. Neurological examination revealed hemiparesis and absence of proprioception on the right side, consistent with central vestibular syndrome. Measurement of blood glucose excluded hypoglycemia due to insulinoma. Contrast-enhanced computed tomography revealed the presence of an intracranial mass, consistent with either granuloma or neoplasia. Palliative treatment with prednisolone yielded no improvement. At postmortem examination, a final diagnosis of a choroid plexus papilloma originating from the fourth ventricle was made. This is the first report of such a tumor in a ferret.


2013 ◽  
Vol 82 (1) ◽  
pp. 9-11
Author(s):  
Jose María González ◽  
Delia Lacasta ◽  
Santiago Sanz ◽  
María Climent ◽  
Alicia Uixera ◽  
...  

Primary neoplasms of the central nervous system have been rarely reported in sheep. A three-year-old Rasa Aragonesa ewe was admitted to the small ruminant external consultancy at the Veterinary Faculty of University of Zaragoza, Spain. Clinical, haematological and neurological examinations were performed. Neurological examination showed signs of ataxia, hyperextension of the right front limb and abnormal postural reactions. The animal was unable to stand and walk, even with help. Patellar and flexor reflexes were normal and superficial sensation was present but decreased. Humanitarian sacrifice was carried out one month later. Gross and histopathological findings revealed a choroid plexus papilloma located in the fourth ventricle of the brain. To the authors’ knowledge this is the first description of this neoplastic disorder in sheep.


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